Regioselective synthesis of multisubstituted isoquinolones and pyridones via Rh(iii)-catalyzed annulation reactions

Substrate Activation Strategies in Rhodium(III)-Catalyzed Selective Functionalization of Arenes

(2015) Guoyong Song et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C–H Functionalizations

(2015) Baihua Ye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Regioselective Syntheses of 1,2-Benzothiazines by Rhodium-Catalyzed Annulation Reactions

(2015) Ying Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd/C-Catalyzed Synthesis of Isoquinolones through CH Activation

(2015) Zhen Shu et al.   ChemCatChem

Rh(iii)-catalyzed C–H activation/cyclization of benzamides and diazo compounds to form isocoumarins and α-pyrones

(2015) Xing Guang Li et al.   CHEMICAL COMMUNICATIONS

Rh(iii)-catalyzed and alcohol-involved carbenoid C–H insertion into N-phenoxyacetamides using α-diazomalonates

(2015) Jie Zhou et al.   CHEMICAL COMMUNICATIONS

C–H bond functionalization based on metal carbene migratory insertion

(2015) Fangdong Hu et al.   CHEMICAL COMMUNICATIONS

One-pot cascade synthesis of N-methoxyisoquinolinediones via Rh(iii)-catalyzed carbenoid insertion C–H activation/cyclization

(2015) Jingjing Shi et al.   CHEMICAL COMMUNICATIONS

Rhodium-Catalyzed C–H Activation of Phenacyl Ammonium Salts Assisted by an Oxidizing C–N Bond: A Combination of Experimental and Theoretical Studies

(2015) Songjie Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(iii)-catalyzed cascade oxidative annulation reactions of aryl imidazolium salts with alkynes involving multiple C–H bond activation

(2015) Qingmei Ge et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Rh(III)-Catalyzed Direct Coupling of Azobenzenes with α-Diazo Esters: Facile Synthesis of Cinnolin-3(2H)-ones

(2015) Satyasheel Sharma et al.   ORGANIC LETTERS

Synthesis of Cinnolin-3(2H)-one Derivatives from Rh-Catalyzed Reaction of Azobenzenes with Diazotized Meldrum’s Acid

(2015) Jeong-Yu Son et al.   ORGANIC LETTERS

Rh(III)-catalyzed C–H alkylation of 2-arylbenzothiazoles with α-diazo esters

(2015) Miji Choi et al.   TETRAHEDRON LETTERS

Synthesis of Sterically Congested Polycyclic Aromatic Hydrocarbons: Rhodium(III)-Catalyzed Cascade Oxidative Annulation of Aryl Ketoximes with Diphenylacetylene by Sequential Cleavage of Multiple CH Bonds

(2014) Bin Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

Regioselective Synthesis of IndolesviaRhodium-Catalyzed CH Activation Directed by anIn-SituGenerated Redox-Neutral Group

(2014) Krishnamoorthy Muralirajan et al.   ADVANCED SYNTHESIS & CATALYSIS

Oxidative Annulation of Anilides with Internal Alkynes Using an (Electron-Deficient η5-Cyclopentadienyl)Rhodium(III) Catalyst Under Ambient Conditions

(2014) Yuki Hoshino et al.   ADVANCED SYNTHESIS & CATALYSIS

Formal SN-Type Reactions in Rhodium(III)-Catalyzed CH Bond Activation

(2014) Nadine Kuhl et al.   ADVANCED SYNTHESIS & CATALYSIS

The CH Activation/1,3-Diyne Strategy: Highly Selective Direct Synthesis of Diverse Bisheterocycles by RhIIICatalysis

(2014) Da-Gang Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Pot Synthesis of Highly Substituted Polyheteroaromatic Compounds by Rhodium(III)-Catalyzed Multiple CH Activation and Annulation

(2014) Jayachandran Jayakumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Isoindolones by Chiral Cyclopentadienyl-Rhodium(III)-Catalyzed CH Functionalizations

(2014) Baihua Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(iii)-catalysed aerobic synthesis of highly functionalized indoles from N-arylurea under mild conditions through C–H activation

(2014) Subban Kathiravan et al.   CHEMICAL COMMUNICATIONS

Rhodium-catalyzed intramolecular annulation via C–H activation leading to fused tricyclic indole scaffolds

(2014) Pengyu Tao et al.   CHEMICAL COMMUNICATIONS

Rhodium(iii)-catalyzed intramolecular amidoarylation and hydroarylation of alkyne via C–H activation: switchable synthesis of 3,4-fused tricyclic indoles and chromans

(2014) Xue Zhang et al.   CHEMICAL COMMUNICATIONS

Rh-Catalyzed oxidative C–H activation/annulation: converting anilines to indoles using molecular oxygen as the sole oxidant

(2014) Guoying Zhang et al.   CHEMICAL COMMUNICATIONS

Rhodium(iii)-catalyzed C2-selective carbenoid functionalization and subsequent C7-alkenylation of indoles

(2014) Jingjing Shi et al.   CHEMICAL COMMUNICATIONS

Rh(iii)-catalyzed synthesis of 1-aminoindole derivatives from 2-acetyl-1-arylhydrazines and diazo compounds in water

(2014) Yujie Liang et al.   CHEMICAL COMMUNICATIONS

Rhodium(III)- and Iridium(III)-Catalyzed C7 Alkylation of Indolines with Diazo Compounds

(2014) Wen Ai  et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium(III)-Catalyzed CH Activation and Indole Synthesis With Hydrazone as an Auto-Formed and Auto-Cleavable Directing Group

(2014) Liyao Zheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium(III)-Catalyzed Intramolecular Redox-Neutral Annulation of Tethered Alkynes: Formal Total Synthesis of (±)-Goniomitine

(2014) Bing Zhou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rh(III)-Catalyzed C–H Activation/Cyclization of Indoles and Pyrroles: Divergent Synthesis of Heterocycles

(2014) Yan Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Indolo[2,1-a]isoquinolines via a Triazene-Directed C–H Annulation Cascade

(2014) Huan Sun et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium-Catalyzed Synthesis of Isoquinolines and Indenes from Benzylidenehydrazones and Internal Alkynes

(2014) Xiao-Cheng Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Tunable Arylative Cyclization of 1,6-Enynes Triggered by Rhodium(III)-Catalyzed C–H Activation

(2014) Yuki Fukui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed Decarboxylative Coupling of Acrylic Acids with Unsaturated Oxime Esters: Carboxylic Acids Serve as Traceless Activators

(2014) Jamie M. Neely et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(iii)-catalyzed formal oxidative [4 + 1] cycloaddition of benzohydroxamic acids and α-diazoesters. A facile synthesis of functionalized benzolactams

(2014) Hon-Wah Lam et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Rh(III)-Catalyzed Intramolecular Redox-Neutral or Oxidative Cyclization of Alkynes: Short, Efficient Synthesis of 3,4-Fused Indole Skeletons

(2014) Bing Zhou et al.   ORGANIC LETTERS

Rhodium(III)-Catalyzed C–C Bond Formation of Quinoline N-Oxides at the C-8 Position under Mild Conditions

(2014) Jisu Jeong et al.   ORGANIC LETTERS

Rh-Catalyzed Sequential Oxidative C–H and N–N Bond Activation: Conversion of Azines into Isoquinolines with Air at Room Temperature

(2014) Wenjia Han et al.   ORGANIC LETTERS

Rhodium-Catalyzed Oxidative Annulation of Hydrazines with Alkynes Using a Nitrobenzene Oxidant

(2014) Deng Yuan Li et al.   ORGANIC LETTERS

Rhodium(III)-Catalyzed C–H Activation/Annulation with Vinyl Esters as an Acetylene Equivalent

(2014) Nicola J. Webb et al.   ORGANIC LETTERS

Rhodium(III)-catalyzed synthesis of indoles from 1-alkylidene-2-arylhydrazines and alkynes via C–H and N–N bond cleavages

(2014) Takanori Matsuda et al.   TETRAHEDRON LETTERS

Rh(iii)-catalyzed C–H functionalization/aromatization cascade with 1,3-dienes: a redox-neutral and regioselective access to isoquinolines

(2014) Dongbing Zhao et al.   Chemical Science

Rh(iii)-catalyzed annulation of N-methoxybenzamides with ynesulfonamides at room temperature: a practical and efficient route to 4-aminoisoquinolone derivatives

(2014) Guangying Tan et al.   RSC Advances

Synthesis of Isoquinoline Derivatives through Rhodium(III)- Catalyzed Reactions of Benzylamines with Non-Terminal Alkynes

(2013) Dong-Su Kim et al.   ADVANCED SYNTHESIS & CATALYSIS

Indole Synthesis by Rhodium(III)-Catalyzed Hydrazine-Directed CH Activation: Redox-Neutral and Traceless by NN Bond Cleavage

(2013) Dongbing Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

General and Efficient Synthesis of Indoles through Triazene-Directed C-H Annulation

(2013) Chengming Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-CatalyzedorthoAlkenylation ofN-Phenoxyacetamides withN-Tosylhydrazones or Diazoesters through CH Activation

(2013) Fangdong Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microwave-Assisted, Rhodium(III)-Catalyzed N-Annulation Reactions of Aryl and α,β-Unsaturated Ketones with Alkynes

(2013) Hyejeong Lee et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium(III)-Catalyzed Synthesis of Cyclopenta[b]pyrroles from 1,2-Diketones, 2-Aminopyridine, and Alkynes

(2013) Juanjuan Du et al.   Chemistry-An Asian Journal

Rhodium(III)-Catalyzed Azacycle-Directed Intermolecular Insertion of Arene C–H Bonds into α-Diazocarbonyl Compounds

(2013) Xinzhang Yu et al.   JOURNAL OF ORGANIC CHEMISTRY

Rh(III)-Catalyzed C–H Activation and Double Directing Group Strategy for the Regioselective Synthesis of Naphthyridinones

(2013) John R. Huckins et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Indole Synthesis Using N–N Bond as an Internal Oxidant

(2013) Baoqing Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed Synthesis of Multisubstituted Isoquinoline and Pyridine N-Oxides from Oximes and Diazo Compounds

(2013) Zhuangzhi Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Coupling of Benzamides and Donor/Acceptor Diazo Compounds To Form γ-Lactams via Rh(III)-Catalyzed C–H Activation

(2013) Todd K. Hyster et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and C2-functionalization of indoles with allylic acetates under rhodium catalysis

(2013) Mirim Kim et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

New and Concise Syntheses of the Bicyclic Oxamazin Core Using an Intramolecular Nitroso Diels–Alder Reaction and Ring-Closing Olefin Metathesis

(2013) Kyle D. Watson et al.   ORGANIC LETTERS

Synthesis of Isoquinolines via Rh(III)-Catalyzed C–H Activation Using Hydrazone as a New Oxidizing Directing Group

(2013) Sheng-Chieh Chuang et al.   ORGANIC LETTERS

Rh(III)-Catalyzed Tandem C–H Allylation and Oxidative Cyclization of Anilides: A New Entry to Indoles

(2013) Ana Cajaraville et al.   ORGANIC LETTERS

Traceless Directing Strategy: Efficient Synthesis of N-Alkyl Indoles via Redox-Neutral C–H Activation

(2013) Chengming Wang et al.   ORGANIC LETTERS

Rhodium(iii)-catalyzed intramolecular annulations involving amide-directed C–H activations: synthetic scope and mechanistic studies

(2013) Noelia Quiñones et al.   Chemical Science

Rh(iii)-catalyzed C–H activation/[4 + 3] cycloaddition of benzamides and vinylcarbenoids: facile synthesis of azepinones

(2013) Sunliang Cui et al.   Chemical Science

Diazo Compounds and N-Tosylhydrazones: Novel Cross-Coupling Partners in Transition-Metal-Catalyzed Reactions

(2012) Qing Xiao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Diverse Reactivity in a Rhodium(III)-Catalyzed Oxidative Coupling ofN-Allyl Arenesulfonamides with Alkynes

(2012) Dongqi Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed Intramolecular Annulation through CH Activation: Total Synthesis of (±)-Antofine, (±)-Septicine, (±)-Tylophorine, and Rosettacin

(2012) Xianxiu Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-catalysed synthesis of isoquinolinones and analogues via C–H and N–H bonds double activation

(2012) Hongban Zhong et al.   CHEMICAL COMMUNICATIONS

C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation

(2012) Guoyong Song et al.   CHEMICAL SOCIETY REVIEWS

Cu–Rh Redox Relay Catalysts for Synthesis of Azaheterocycles via C–H Functionalization

(2012) Shunsuke Chiba   CHEMISTRY LETTERS

Ruthenium-Catalyzed Oxidative Coupling/Cyclization of Isoquinolones with Alkynes through CH/NH Activation: Mechanism Study and Synthesis of Dibenzo[a,g]quinolizin-8-one Derivatives

(2012) Bin Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Isoquinolines and Heterocycle-Fused Pyridines via Three-Component Cascade Reaction of Aryl Ketones, Hydroxylamine, and Alkynes

(2012) Liyao Zheng et al.   JOURNAL OF ORGANIC CHEMISTRY

Rh(III)-Catalyzed Regioselective Synthesis of Pyridines from Alkenes and α,β-Unsaturated Oxime Esters

(2012) Jamie M. Neely et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh-Catalyzed Intermolecular Carbenoid Functionalization of Aromatic C–H Bonds by α-Diazomalonates

(2012) Wai-Wing Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mild Rh(III)-Catalyzed C–H Activation and Annulation with Alkyne MIDA Boronates: Short, Efficient Synthesis of Heterocyclic Boronic Acid Derivatives

(2012) Honggen Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Cascade Oxidative Annulation Leading to Substituted Naphtho[1,8-bc]pyrans by Sequential Cleavage of C(sp2)–H/C(sp3)–H and C(sp2)–H/O–H Bonds

(2012) Xing Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium-Catalyzed Oxidative C–H Bond Olefination of N-Methoxybenzamides Using an Oxidizing Directing Group

(2012) Bin Li et al.   ORGANIC LETTERS

Synthesis of Isoquinolines via Rhodium(III)-Catalyzed Dehydrative CC and CN Coupling between Oximines and Alkynes

(2011) Xingping Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Isoquinolines from α-Aryl Vinyl Azides and Internal Alkynes by Rh-Cu Bimetallic Cooperation

(2011) Yi-Feng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pyridine synthesis from oximes and alkynesviarhodium(iii) catalysis: Cp* and Cptprovide complementary selectivity

(2011) Todd K. Hyster et al.   CHEMICAL COMMUNICATIONS

Guiding principles for site selective and stereoselective intermolecular C–H functionalization by donor/acceptor rhodium carbenes

(2011) Huw M. L. Davies et al.   CHEMICAL SOCIETY REVIEWS

Rhodium-catalyzed Oxidative Coupling of Benzylamines with Alkynes through Dehydrogenation and Dehydrogenative Cyclization

(2011) Keisuke Morimoto et al.   CHEMISTRY LETTERS

Ruthenium-Catalyzed Isoquinolone Synthesis through CH Activation Using an Oxidizing Directing Group

(2011) Bin Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Oxidative Coupling of NH Isoquinolones with Olefins Catalyzed by Rh(III)

(2011) Fen Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Azaheterocycles from Aryl KetoneO-Acetyl Oximes and Internal Alkynes by Cu–Rh Bimetallic Relay Catalysts

(2011) Pei Chui Too et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium(III)-Catalyzed Heterocycle Synthesis Using an Internal Oxidant: Improved Reactivity and Mechanistic Studies

(2011) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 1-Aminoisoquinolines via Rh(III)-Catalyzed Oxidative Coupling

(2011) Xiaohong Wei et al.   ORGANIC LETTERS

An improved catalyst architecture for rhodium(iii) catalyzed C–H activation and its application to pyridone synthesis

(2011) Todd K. Hyster et al.   Chemical Science

The Vinyl Moiety as a Handle for Regiocontrol in the Preparation of Unsymmetrical 2,3-Aliphatic-Substituted Indoles and Pyrroles

(2010) Malcolm P. Huestis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-catalyzed Oxidative Coupling/Cyclization of Benzamides with Alkynes via C–H Bond Cleavage

(2010) Satoshi Mochida et al.   CHEMISTRY LETTERS

Oxidative Coupling of Aromatic Substrates with Alkynes and Alkenes under Rhodium Catalysis

(2010) Tetsuya Satoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rh-Catalyzed Oxidative Coupling between Primary and Secondary Benzamides and Alkynes: Synthesis of Polycyclic Amides

(2010) Guoyong Song et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium(III)-Catalyzed Isoquinolone Synthesis: The N−O Bond as a Handle for C−N Bond Formation and Catalyst Turnover

(2010) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Arene and Alkene C−H Bond Functionalization Leading to Indoles and Pyrroles

(2010) David R. Stuart et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Oxidative Cycloaddition of Benzamides and Alkynes via C−H/N−H Activation

(2010) Todd K. Hyster et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pyrrole Synthesis via Allylic sp3C−H Activation of Enamines Followed by Intermolecular Coupling with Unactivated Alkynes

(2010) Souvik Rakshit et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 2-Pyridones and Iminoesters via Rh(III)-Catalyzed Oxidative Coupling between Acrylamides and Alkynes

(2010) Yan Su et al.   ORGANIC LETTERS

Rh(III)-Catalyzed Oxidative Coupling ofN-Aryl-2-aminopyridine with Alkynes and Alkenes

(2010) Jinlei Chen et al.   ORGANIC LETTERS

Rhodium(III)-Catalyzed Synthesis of Isoquinolines from Aryl KetoneO-Acyloxime Derivatives and Internal Alkynes

(2010) Pei Chui Too et al.   ORGANIC LETTERS

Rhodium-catalyzed oxidative coupling of aromatic imines with internal alkynes via regioselective C–H bond cleavage

(2009) Tatsuya Fukutani et al.   CHEMICAL COMMUNICATIONS

Catalytic Carbene Insertion into C−H Bonds

(2009) Michael P. Doyle et al.   CHEMICAL REVIEWS

Isoquinoline Synthesis via Rhodium-Catalyzed Oxidative Cross-Coupling/Cyclization of Aryl Aldimines and Alkynes

(2009) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Efficient One-Pot Copper-Catalyzed Approach to Isoquinolin-1(2H)-one Derivatives

(2009) Feng Wang et al.   ORGANIC LETTERS

Indole Synthesis via Rhodium Catalyzed Oxidative Coupling of Acetanilides and Internal Alkynes

(2008) David R. Stuart et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion

(2008) Huw M. L. Davies et al.   NATURE