A pilot study to determine the optimal dose of scAAVIL-1ra in a large animal model of post-traumatic osteoarthritis

Examining the Effects of the Oral Supplement Biota orientalis in the Osteochondral Fragment-Exercise Model of Osteoarthritis in the Horse

(2022) Kathryn A. Seabaugh et al.   Frontiers in Veterinary Science

Advantages and challenges of stem cell therapy for osteoarthritis (Review)

(2021) Stephanie Loo et al.   Biomedical Reports

Role of Innate Immunity in Initiation and Progression of Osteoarthritis, with Emphasis on Horses

(2021) Juan Estrada McDermott et al.   Animals

The role of macrophages in osteoarthritis and cartilage repair

(2020) C.-L. Wu et al.   OSTEOARTHRITIS AND CARTILAGE

Recent advances in articular cartilage evaluation using computed tomography and magnetic resonance imaging

(2018) B. B. Nelson et al.   EQUINE VETERINARY JOURNAL

Self-Complementary Adeno-Associated Virus–Mediated Interleukin-1 Receptor Antagonist Gene Delivery for the Treatment of Osteoarthritis: Test of Efficacy in an Equine Model

(2018) Rachael S. Watson Levings et al.   Human Gene Therapy Clinical Development

Gene Therapy for Osteoarthritis: Pharmacokinetics of Intra-Articular Self-Complementary Adeno-Associated Virus Interleukin-1 Receptor Antagonist Delivery in an Equine Model

(2018) Rachael S. Watson Levings et al.   Human Gene Therapy Clinical Development

Use of contrast media in computed tomography and magnetic resonance imaging in horses: Techniques, adverse events and opportunities

(2017) B. B. Nelson et al.   EQUINE VETERINARY JOURNAL

Articular cartilage repair: Current needs, methods and research directions

(2017) Diego Correa et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Adeno-associated virus gene therapy vector scAAVIGF-I for transduction of equine articular chondrocytes and RNA-seq analysis

(2016) D.D. Hemphill et al.   OSTEOARTHRITIS AND CARTILAGE

Alternative Methods for Defining Osteoarthritis and the Impact on Estimating Prevalence in a US Population-Based Survey

(2016) Miriam G. Cisternas et al.   ARTHRITIS CARE & RESEARCH

Targets, models and challenges in osteoarthritis research

(2015) S. Thysen et al.   Disease Models & Mechanisms

scAAVIL-1ra dosing trial in a large animal model and validation of long-term expression with repeat administration for osteoarthritis therapy

(2015) L R Goodrich et al.   GENE THERAPY

Persistence, Localization, and External Control of Transgene Expression After Single Injection of Adeno-Associated Virus into Injured Joints

(2013) Hannah H. Lee et al.   HUMAN GENE THERAPY

Pharmacologic treatment of osteoarthritis

(2013) Seung-Hoon Baek et al.   JOURNAL OF THE KOREAN MEDICAL ASSOCIATION

The horse as a model of naturally occurring osteoarthritis

(2013) C. W. McIlwraith et al.   Bone & Joint Research

Optimization of scAAVIL-1ra In Vitro and In Vivo to Deliver High Levels of Therapeutic Protein for Treatment of Osteoarthritis

(2013) Laurie R Goodrich et al.   Molecular Therapy-Nucleic Acids

The role of synovitis in osteoarthritis pathogenesis

(2012) Carla R. Scanzello et al.   BONE

scAAV-mediated gene transfer of interleukin-1-receptor antagonist to synovium and articular cartilage in large mammalian joints

(2012) R S Watson et al.   GENE THERAPY

Comparative study of depth-dependent characteristics of equine and human osteochondral tissue from the medial and lateral femoral condyles

(2012) J. Malda et al.   OSTEOARTHRITIS AND CARTILAGE

Prostaglandin E2 and Pain—An Update

(2011) Atsufumi Kawabata   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Post-traumatic osteoarthritis: Improved understanding and opportunities for early intervention

(2011) Donald D. Anderson et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Single intra-articular injection of adeno-associated virus results in stable and controllable in vivo transgene expression in normal rat knees

(2011) K.A. Payne et al.   OSTEOARTHRITIS AND CARTILAGE

Induction of Rapid and Highly Efficient Expression of the Human ND4 Complex I Subunit in the Mouse Visual System by Self-complementary Adeno-Associated Virus

(2010) Rajeshwari D. Koilkonda   ARCHIVES OF OPHTHALMOLOGY

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the horse

(2010) C.W. McIlwraith et al.   OSTEOARTHRITIS AND CARTILAGE

Intraarticular injection of anakinra in osteoarthritis of the knee: A multicenter, randomized, double-blind, placebo-controlled study

(2009) X. Chevalier et al.   ARTHRITIS AND RHEUMATISM

Insurer and out-of-pocket costs of osteoarthritis in the US: Evidence from national survey data

(2009) Harry Kotlarz et al.   ARTHRITIS AND RHEUMATISM

Intra-articular gene delivery and expression of interleukin-1Ra mediated by self-complementary adeno-associated virus

(2009) Jesse D. Kay et al.   JOURNAL OF GENE MEDICINE

Changes in synovial fluid and serum biomarkers with exercise and early osteoarthritis in horses

(2008) D.D. Frisbie et al.   OSTEOARTHRITIS AND CARTILAGE

Preclinical animal models in single site cartilage defect testing: a systematic review

(2008) B.J. Ahern et al.   OSTEOARTHRITIS AND CARTILAGE

The contribution of the synovium, synovial derived inflammatory cytokines and neuropeptides to the pathogenesis of osteoarthritis

(2007) Saski Sutton et al.   VETERINARY JOURNAL