Indole–pyridine carbonitriles: multicomponent reaction synthesis and bio-evaluation as potential hits against diabetes mellitus

Isatin thiazoles as antidiabetic: Synthesis, in vitro enzyme inhibitory activities, kinetics, and in silico studies

(2022) Mehwish Solangi et al.   ARCHIV DER PHARMAZIE

Hydrazinyl thiazole linked indenoquinoxaline hybrids: Potential leads to treat hyperglycemia and oxidative stress; Multistep synthesis, α-amylase, α-glucosidase inhibitory and antioxidant activities

(2022) Shehryar Hameed et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synthesis and biological activity of new indole based derivatives as potent anticancer, antioxidant and antimicrobial agents

(2022) Metin Konus et al.   JOURNAL OF MOLECULAR STRUCTURE

Dicyanoanilines as potential and dual inhibitors of α-amylase and α-glucosidase enzymes: Synthesis, characterization, in vitro, in silico, and kinetics studies

(2021) Faiza Saleem et al.   Arabian Journal of Chemistry

Oxidative stress – A unifying paradigm in hypertension

(2020) Rhian M. Touyz et al.   CANADIAN JOURNAL OF CARDIOLOGY

Potential Effect of Hydroxychloroquine in Diabetes Mellitus: A Systematic Review on Preclinical and Clinical Trial Studies

(2020) Dawit Zewdu Wondafrash et al.   Journal of Diabetes Research

Synthesis, in vitro and in silico screening of 2-amino-4-aryl-6-(phenylthio) pyridine-3,5-dicarbonitriles as novel α-glucosidase inhibitors

(2020) Muhammad Ali et al.   BIOORGANIC CHEMISTRY

Oxidative Stress in Cancer

(2020) John D. Hayes et al.   CANCER CELL

Synthesis of azachalcones, their α-amylase, α-glucosidase inhibitory activities, kinetics, and molecular docking studies

(2020) Faiza Saleem et al.   BIOORGANIC CHEMISTRY

Multicomponent reactions (MCR) in medicinal chemistry: a patent review (2010-2020)

(2020) Hafiza Amna Younus et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Discovery of pyridoxal reductase activity as part of human vitamin B6 metabolism

(2019) Rúben J. Ramos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

New Series of Thiazole Derivatives: Synthesis, Structural Elucidation, Antimicrobial Activity, Molecular Modeling and MOE Docking

(2019) Ismail Althagafi et al.   MOLECULES

Synthesis and Molecular Docking Studies of Novel Triazole Derivatives as Antioxidant Agents

(2019) Musa Özil et al.   LETTERS IN ORGANIC CHEMISTRY

Early Outcomes From the English National Health Service Diabetes Prevention Programme

(2019) Jonathan Valabhji et al.   DIABETES CARE

Ageing, age-related diseases and oxidative stress: What to do next?

(2019) Jiao Luo et al.   AGEING RESEARCH REVIEWS

Catalytic asymmetric synthesis of indole derivatives as novel α -glucosidase inhibitors in vitro

(2018) Mohammad Shahidul Islam et al.   BIOORGANIC CHEMISTRY

A simple and efficient synthesis of benzimidazoles containing piperazine or morpholine skeleton at C-6 position as glucosidase inhibitors with antioxidant activity

(2018) Musa Özil et al.   BIOORGANIC CHEMISTRY

IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045

(2018) N.H. Cho et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Oxidative stress, aging, and diseases

(2018) Ilaria Liguori et al.   Clinical Interventions in Aging

New indole based hybrid oxadiazole scaffolds with N-substituted acetamides: As potent anti-diabetic agents

(2018) Majid Nazir et al.   BIOORGANIC CHEMISTRY

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Gregory A Roth et al.   LANCET

Synthesis and anticholinesterase activity of coumarin-3-carboxamides bearing tryptamine moiety

(2016) Samaneh Ghanei-Nasab et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Interactions between kidney disease and diabetes: dangerous liaisons

(2016) Roberto Pecoits-Filho et al.   Diabetology & Metabolic Syndrome

Synthesis of diethyl 4-substituted-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates as a new series of inhibitors against yeast α-glucosidase

(2015) Huma Niaz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A review on recent developments of indole-containing antiviral agents

(2015) Ming-Zhi Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Methods of measurement and evaluation of natural antioxidant capacity/activity (IUPAC Technical Report)

(2013) Reşat Apak et al.   PURE AND APPLIED CHEMISTRY

Chemistry and Biology Of Multicomponent Reactions

(2012) Alexander Dömling et al.   CHEMICAL REVIEWS

Four-Component Synthesis of Star-Shaped 2-(Indol-3-yl)pyridine Derivatives in One Pot

(2012) Li-Yan Zeng et al.   SYNTHETIC COMMUNICATIONS

Synthesis and Antiviral Activity of New Indole-Based Heterocycles

(2010) Hassan Abdel-Gawad et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Multicomponent reactions for the synthesis of pyrroles

(2010) Verónica Estévez et al.   CHEMICAL SOCIETY REVIEWS

Biological importance of the indole nucleus in recent years: A comprehensive review

(2010) Vikas Sharma et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

6-(1H-Indol-3-yl)-4-phenyl-2,2′-bipyridine-5-carbonitrile

(2009) Weijun Zhu et al.   ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE

Effective Control of Type 2 Diabetes through Antioxidant Defense by Edible Fruits ofDiospyros peregrina

(2009) Saikat Dewanjee et al.   Evidence-based Complementary and Alternative Medicine

Simple and Convenient Approach to the Kr€ohnke Pyridine Type Synthesis of Functionalized Indol-3-yl Pyridine Derivatives Using 3-Cyanoacetyl Indole

(2009) Prakasam Thirumurugan et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

A simple one-pot synthesis of functionalised 6-(indol-3-yl)-2,2′-bipyridine derivatives via multi-component reaction under neat condition

(2009) Prakasam Thirumurugan et al.   TETRAHEDRON LETTERS

Alternative Catalytic Anions Differentially Modulate Human α-Amylase Activity and Specificity†,‡

(2008) Robert Maurus et al.   BIOCHEMISTRY

Lessons Learnt from Assembling Screening Libraries for Drug Discovery for Neglected Diseases

(2007) Ruth Brenk et al.   ChemMedChem