Article
Substance Abuse
Amanda M. Palmer, Rachel L. Tomko, Lindsay M. Squeglia, Kevin M. Gray, Matthew J. Carpenter, Tracy T. Smith, Jennifer Dahne, Benjamin A. Toll, Erin A. McClure
Summary: This pilot study examines the feasibility and acceptability of a telehealth-based vaping cessation intervention for young adults. The results indicate that contingency management delivered via smartphone app shows promise in promoting vaping cessation among youth. However, there were no significant differences in abstinence rates between the intervention group and the control group at the end of treatment and follow-up.
DRUG AND ALCOHOL DEPENDENCE
(2022)
Review
Psychiatry
Josefien Johanna Froukje Breedvelt, Maria Elisabeth Brouwer, Mathias Harrer, Maria Semkovska, David Daniel Ebert, Pim Cuijpers, Claudi Louisa Hermina Bockting
Summary: Psychological interventions do not increase the risk of depressive relapse when tapering antidepressants, and adding psychological interventions to antidepressants significantly reduces the risk of relapse compared to antidepressants alone. These findings are relevant for patients, clinicians, and guideline developers as neither strategy is routinely implemented.
BRITISH JOURNAL OF PSYCHIATRY
(2021)
Article
Psychology, Clinical
Eric Malbos, Baptiste Borwell, Melodie Einig-Iscain, Theo Korchia, Robin Cantalupi, Laurent Boyer, Christophe Lancon
Summary: The study found that virtual reality cue exposure therapy combined with cognitive behavioral therapy is effective in preventing smoking relapse, with virtual environments effectively simulating risk situations and aiding in reducing relapse rates. The results showed that VRCE is at least as efficacious as traditional CBT in terms of craving reduction and decrease in nicotine dependence, with lower dropout and relapse rates in the VRCE group compared to the CBT group.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Environmental Sciences
Christina Gallinat, Markus Moessner, Sandra Apondo, Philipp A. Thomann, Sabine C. Herpertz, Stephanie Bauer
Summary: Schizophrenia is a severe mental illness with high symptom burden and relapse rates. Digital interventions are increasingly seen as a way to support long-term disease management. A pilot study on a mobile and internet-based aftercare program showed overall positive attitudes and good adherence among participants, despite slow enrollment.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Review
Medicine, General & Internal
Javier Conejo-Galindo, Alejandro Sanz-Giancola, Miguel Angel Alvarez-Mon, Miguel A. Ortega, Luis Gutierrez-Rojas, Guillermo Lahera
Summary: Pregnancy and postpartum are critical periods with a high risk of relapse for bipolar disorder patients, with a particularly high risk of postpartum relapse. It is important to detect and treat decompensation in this period.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Psychiatry
Kristin Muhlner, Jeff DeFlavio, Alfonso Ang, Michael Zito, A. Thomas McLellan, Brian Perrochet
Summary: This study evaluated a digital, all-virtual program for the treatment of methamphetamine use disorder (MUD) and found that it effectively helped individuals reduce or stop their methamphetamine use. The program included counseling, app-based therapeutic tasks, remote drug testing, medical oversight, and contingency management procedures. Results showed that participants were more likely to test negative for meth use throughout the program and reported improved well-being and social functioning. The program was efficiently implemented and well-received by participants and clinical personnel, demonstrating its ability to provide comprehensive and effective care for individuals with MUD.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Public, Environmental & Occupational Health
Rajshree Thapa, Ayse Zengin, Dinesh Neupane, Shiva Raj Mishra, Sweta Koirala, Per Kallestrup, Amanda G. Thrift
Summary: A 12-month lifestyle intervention in Nepal led by community health workers effectively reduced blood pressure, but the benefits were not maintained in the long term after the intervention ceased.
LANCET GLOBAL HEALTH
(2023)
Article
Psychology, Multidisciplinary
Sunniva Brurok Myklebost, Tine Nordgreen, Oda Stakkestad Klakegg, Asa Hammar
Summary: This study examined the long-term effects of an internet-delivered intervention on residual cognitive deficits, rumination, and symptoms of major depressive disorder (MDD). The results showed a reduction in cognitive deficits and rumination, but an increase in symptoms of MDD. Additionally, participants who experienced a new episode of MDD showed different outcomes compared to those who did not.
FRONTIERS IN PSYCHOLOGY
(2023)
Review
Multidisciplinary Sciences
Daniel Lopez de Romana, Alison Mildon, Jenna Golan, Maria Elena D. Jefferds, Lisa M. Rogers, Mandana Arabi
Summary: Anemia remains a major public health problem, especially in low- and middle-income countries. The World Health Organization recommends several interventions to prevent and manage anemia in vulnerable population groups. These interventions include iron supplementation, micronutrient powders, fortification of flour, and non-nutrition-related interventions such as malaria treatment and deworming. Promising interventions for anemia prevention include vitamin A supplementation, multiple micronutrient supplementation, lipid-based supplements, and fortification of salt. Future research is needed to address efficacy and safety of supplementation formulations and investigate the effectiveness of integrating control programs for various diseases.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2023)
Article
Psychology, Clinical
Margot J. Wagenmakers, Mardien L. Oudega, Filip Bouckaert, Didi Rhebergen, Aartjan T. F. Beekman, Dick J. Veltman, Pascal Sienaert, Eric van Exel, Annemieke Dols
Summary: Patients with psychotic late-life depression (LLD) treated with electroconvulsive therapy (ECT) exhibit higher remission rates compared to patients with nonpsychotic LLD. The superior efficacy in psychotic LLD is not attributed to a shorter index episode duration.
JOURNAL OF CLINICAL PSYCHIATRY
(2022)
Article
Psychiatry
Thrinath Mullapudi, Monojit Debnath, Ramajayam Govindaraj, Praveen Raj, Moinak Banerjee, Shivarama Varambally
Summary: This study aimed to explore the effects of add-on yoga therapy on the immune inflammatory pathway in schizophrenia patients. The results showed that patients in the yoga group had significant reductions in plasma TNF-α and IL-5 levels, and greater clinical improvements compared to the control group. Further analysis revealed a positive correlation between TNF-α levels and negative symptoms and socio-occupational functioning in the yoga group.
ASIAN JOURNAL OF PSYCHIATRY
(2023)
Article
Substance Abuse
Michael BR. Schmidt, Emily R. R. Grekin, Mark A. A. Lumley
Summary: A brief web-based mindfulness intervention for smoking cessation was tested and found to be effective in helping participants control craving for cigarettes, although it did not significantly reduce smoking quantity. The intervention is easy to disseminate and has the potential to reach a large number of smokers.
SUBSTANCE USE & MISUSE
(2023)
Article
Rehabilitation
Pablo Rodriguez Sanchez-Laulhe, Angela Biscarri-Carbonero, Alejandro Suero-Pineda, Luis G. Luque-Romero, Francisco J. Barrero Garcia, Jesus Blanquero, Alberto M. Heredia-Rizo
Summary: A mobile app-delivered intervention has positive effects on hand function and pain measures in patients with hand osteoarthritis compared to usual care. The intervention improves hand function, upper limb function, and reduces pain.
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
(2023)
Article
Clinical Neurology
S. Darius Tandon, Molly McGown, Laura Campbell, Justin D. Smith, Chen Yeh, Carol Brady
Summary: The study shows that Mothers and Babies 1-on-1 delivered by lay home visitors can lead to reductions in perceived stress and depressive symptoms among pregnant women. However, challenges such as client recruitment and retention need to be addressed for successful implementation.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychology, Clinical
Mike Lucock, Rachel Borthwick, Jade Cupac, Ruth Elliott, Rebecca Howell, Sarah Kendal, Wajid Khan, David Sandford, Bethany Tolley
Summary: The study provides evidence of the effectiveness of a brief relapse prevention intervention using implementation intentions, following remission from depression. Seven themes were identified that highlighted effective relapse prevention strategies and effective implementation of the intervention. Further research, such as a randomized controlled trial, is needed to confirm the findings.
PSYCHOTHERAPY RESEARCH
(2022)
Article
Substance Abuse
John J. Mariani, Martina Pavlicova, Cale Basaraba, Agnieszka Mamczur-Fuller, Daniel J. Brooks, Adam Bisaga, Kenneth M. Carpenter, Edward Nunes, Frances R. Levin
Summary: The pilot study showed that high-dose gabapentin was more effective in reducing harmful alcohol consumption and increasing percent days abstinent in actively drinking outpatients with AUD.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
(2021)
Article
Substance Abuse
Frances R. Levin, John J. Mariani, C. Jean Choi, Cale Basaraba, Daniel J. Brooks, Christina A. Brezing, Martina Pavlicova
Summary: This study explores the feasibility of using reductions in self-reported days of cannabis use as a viable outcome measure for Cannabis Use Disorder treatment. The results showed that individuals on active medication were more likely to transition from heavy to moderate use towards the end of each trial, indicating that certain medications may have a greater impact than previously assessed. Future studies should further investigate if this pattern is associated with reduced CUD severity and/or improved quality of life.
DRUG AND ALCOHOL DEPENDENCE
(2021)
Article
Substance Abuse
John J. Mariani, Amy L. Mahony, Samuel C. Podell, Daniel J. Brooks, Christina Brezing, Sean X. Luo, Nasir H. Naqvi, Frances R. Levin
Summary: This study demonstrated the feasibility of inducing heroin-containing fentanyl users onto 300 mg BXR injection treatment in a single day, and all participants remained engaged in the study for the full 3 months post-induction. The ability to administer long-acting BXR injections that ensure therapeutic serum levels for a month on the first day of treatment contact is a promising development for OUD treatment.
AMERICAN JOURNAL ON ADDICTIONS
(2021)
Article
Health Care Sciences & Services
Hilary Luderer, Lisa Chiodo, Amanda Wilson, Christina Brezing, Suky Martinez, Xiaorui Xiong, Robert Gerwien, Bruce Imbert, Mark Deeg, Yuri Maricich, Aimee Campbell
Summary: This study aims to investigate how participants interact with a new content delivery format of a prescription digital therapeutic for opioid use disorder. The study will evaluate treatment success, symptoms of co-occurring mental health disorders, recovery capital, and skill development. A decentralized, randomized controlled trial design will be utilized to compare patient engagement with the new digital therapeutic and the existing one. The results will provide insights into the effectiveness of the different digital therapeutics.
JMIR RESEARCH PROTOCOLS
(2022)
Article
Psychology, Clinical
Arthur Robin Williams, Shoshana V. Aronowitz, Christopher Rowe, Ryan Gallagher, Emily Behar, Adam Bisaga
Summary: This study analyzed 180-day and 365-day retention in the treatment of opioid use disorder (OUD) using a virtual telehealth platform in Pennsylvania and New York. The findings showed that telehealth services for buprenorphine had high retention rates regardless of geography or race/ethnicity. However, age differences indicated that some patients may benefit from more intensive services early in care.
AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE
(2023)
Article
Substance Abuse
Christina A. Brezing, Mohammad Sibai, C. Jean Choi, Souparno Mitra, John J. Mariani, Nasir Naqvi, Amy L. Mahony, Daniel Brooks, Martina Pavlicova, Frances R. Levin
Summary: This study tested the tolerability and effects of the 5HT2c agonist lorcaserin in patients with CUD. The medication was well tolerated in male patients, but not in females. The frequency of cannabis use significantly decreased in the participants.
JOURNAL OF SUBSTANCE USE
(2023)
Article
Psychology, Multidisciplinary
Kenneth M. Carpenter, Richard W. Foltin, Margaret Haney, Suzette M. Evans
Summary: This study investigated how environmental stimuli can influence drug use and found that stimuli paired with smoked cocaine caused changes in heart rate among some participants. These findings have important implications for understanding how stimuli can trigger cocaine use and developing interventions for cocaine use disorder.
PSYCHOLOGICAL RECORD
(2023)
Article
Substance Abuse
John J. Mariani, Robert L. Dobbins, Amy Heath, Frank Gray, Howard Hassman
Summary: This study shows that rapid induction of extended-release buprenorphine treatment is feasible and well-tolerated for patients with opioid use disorder, regardless of their fentanyl use status. The results suggest comparable patient retention and clinical response following single-day induction of BUP-XR for patients who are fentanyl-positive and fentanyl-negative.
AMERICAN JOURNAL ON ADDICTIONS
(2023)
Article
Substance Abuse
John J. Mariani, Amy Mahony, Muhammad N. Iqbal, Sean X. Luo, Nasir H. Naqvi, Frances R. Levin
AMERICAN JOURNAL ON ADDICTIONS
(2020)