Article
Public, Environmental & Occupational Health
Hadeer Meshaal, Emad Salah, Eman Fawzy, Mazen Abdel-Rasheed, Ahmed Maged, Hany Saad
Summary: Hysteroscopic management of first-trimester pregnancy loss is more effective than ultrasound-guided surgical evacuation in removing conception remnants and improving fertility outcomes. Compared to blind evacuation, hysteroscopic management requires a shorter time interval to conceive and reduces the need for further treatment.
Review
Medicine, General & Internal
Sarah Cullen, Katarzyna Sobczyk, Rachel Elebert, Deborah Tarleton, Brenda Casey, Sam Doyle, David Crosby, Cathy Allen
Summary: This study reviewed 106 cases of second-trimester miscarriage and found that establishing the cause of miscarriage can be challenging despite completing all recommended investigations. However, the outcomes in subsequent pregnancies were reassuring, with the majority of women able to have a live birth. This study highlights the importance of conducting all recommended investigations to determine the cause of second-trimester miscarriage and underlines the need for further research in this area.
IRISH JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Environmental Sciences
Olivera Iordache, Diana Maria Anastasiu-Popov, Doru Mihai Anastasiu, Marius Craina, George Dahma, Geanina Sacarin, Carmen Silaghi, Cosmin Citu, Razvan Daniluc, Denisa Hinoveanu, Bogdan Feciche, Felix Bratosin, Radu Neamtu
Summary: Recurrent Pregnancy Loss (RPL) affects a small percentage of women and is believed to be influenced by various genetic and environmental factors. This study aimed to identify genetic mutations associated with RPL during different trimesters of pregnancy. The findings revealed specific mutations that were more prevalent in either the first or second trimester. While certain thrombotic disorders were considered risk factors for RPL, effective interventions have yet to be established.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Obstetrics & Gynecology
Marie Carbonnel, Paul Pirtea, Dominique de Ziegler, Jean Marc Ayoubi
Summary: Both congenital and acquired uterine anomalies are associated with recurrent pregnancy loss. Initial evaluation of uterine anatomy is crucial for women with RPL. Surgical management of certain uterine anomalies, such as uterine septa, endometrial polyps, intrauterine adhesions, and submucosal myomas, may improve subsequent pregnancy outcomes in specific circumstances.
FERTILITY AND STERILITY
(2021)
Article
Obstetrics & Gynecology
Ali Abbara, Maya Al-Memar, Maria Phylactou, Christopher Kyriacou, Pei Chia Eng, Rans Nadir, Chioma Izzi-Engbeaya, Sophie A. Clarke, Edouard G. Mills, Elisabeth Daniels, Lechun Huo, Ewa Pacuszka, Lisa Yang, Bijal Patel, Tricia An, Paul Bech, Alexander N. Comninos, Hanine Fourie, Tom W. Kelsey, Tom Bourne, Waljit S. Dhillo
Summary: This study compared the performance of Kisspeptin and beta hCG as biomarkers for miscarriage in the first trimester, finding that Kisspeptin showed better performance, especially in later gestational weeks. The conclusion suggests that Kisspeptin is a promising biomarker for miscarriage, and combining it with beta hCG improves prediction accuracy.
FERTILITY AND STERILITY
(2021)
Article
Integrative & Complementary Medicine
Xueqin Gong, Yulong Qian, Liang Zhang, Liping Zhang
Summary: The study demonstrates that UACE combined with ultrasound-guided curettage for cervical pregnancy can improve treatment efficacy, reduce intraoperative bleeding, and enhance recovery time for postoperative symptoms. Gestational week, maximum diameter of gestational sac, and thinnest myometrium are independent factors affecting postoperative recovery of patients.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2021)
Editorial Material
Obstetrics & Gynecology
Dominique de Ziegler, Rene F. Frydman
Summary: Recurrent pregnancy loss (RPL) is defined as two to three spontaneous pregnancy terminations before 12 weeks of gestation, potentially caused by factors like gamete quality, uterine issues, endometrial receptivity alterations, immunologic factors, and thrombophilia.
FERTILITY AND STERILITY
(2021)
Article
Obstetrics & Gynecology
Rima K. Dhillon-Smith, Pedro Melo, Rosinder Kaur, Emily Fox, Adam Devall, Natalie Woodhead, Arri Coomarasamy
Summary: Miscarriage can have devastating physical and psychological impacts, but there are lifestyle and therapeutic interventions available to prevent it.
FERTILITY AND STERILITY
(2023)
Review
Medicine, General & Internal
Akbayan Turesheva, Gulzhanat Aimagambetova, Talshyn Ukybassova, Aizada Marat, Perizat Kanabekova, Lyazzat Kaldygulova, Ainur Amanzholkyzy, Svetlana Ryzhkova, Anastassiya Nogay, Zaituna Khamidullina, Aktoty Ilmaliyeva, Wassim Y. Almawi, Kuralay Atageldiyeva
Summary: Recurrent pregnancy loss is a complex health challenge with no universally accepted definition. The true incidence is difficult to estimate due to inconsistency in definitions and criteria applied by international guidelines. The exact etiology remains questionable and up to 75% of cases are unexplained. This review aimed to summarize accumulated knowledge on etiology, risk factors, diagnostic options, and management approach to recurrent pregnancy loss.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Haley G. Genovese, Dana B. Mcqueen
Summary: This manuscript reports on the prevalence of early pregnancy loss and discusses the impact of improved pregnancy diagnosis, as well as the influence of increased age and body mass index at first birth.
FERTILITY AND STERILITY
(2023)
Article
Immunology
Yutoku Shi, Hideto Yamada, Yuki Sasagawa, Kenji Tanimura, Masashi Deguchi
Summary: This study found that an increase in Ureaplasma species in the uterine endometrium microbiota of women with recurrent pregnancy loss was associated with a higher risk of miscarriage with normal chromosome karyotype and preterm delivery in subsequent pregnancies. Analyzing UEM in women with recurrent pregnancy loss before pregnancy may help identify microbiota associated with adverse pregnancy outcomes.
JOURNAL OF REPRODUCTIVE IMMUNOLOGY
(2022)
Article
Obstetrics & Gynecology
Dana B. McQueen, Kruti P. Maniar, Anne Hutchinson, Rafael Confino, Lia Bernardi, Mary Ellen Pavone
Summary: The study aimed to develop diagnostic criteria for chronic endometritis and compare its prevalence between women with recurrent pregnancy loss (RPL) and controls. Results showed that with strict diagnostic criteria, the prevalence of chronic endometritis was significantly higher in women with RPL, indicating an association between chronic endometritis and RPL.
FERTILITY AND STERILITY
(2021)
Article
Obstetrics & Gynecology
Kilian Vomstein, Pia Egerup, Astrid Marie Kolte, Ida Behrendt-Moller, Amalie Dyhrberg Boje, Marie-Louise Bertelsen, Cecilie Sofie Eriken, Michelle Raupelyt Reierson, Bettina Toth, Nina la Cour Freiesleben, Henriette Svarre Nielsen
Summary: This study investigated the differences in menstrual blood lymphocytes between controls, patients with recurrent pregnancy loss (RPL), and patients with unexplained infertility (uINF). The results showed that RPL patients had significantly higher numbers of CD56+ NK cells in menstrual blood compared to controls, while both RPL and uINF patients had decreased numbers of CD56dimCD16bright NK cells in menstrual blood. These findings suggest altered cytotoxicity in menstrual blood NK cell subtypes of RPL and uINF patients compared to controls.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Medicine, General & Internal
Kelly Steinfort, Ellen Van Houtven, Yves Jacquemyn, Bettina Blaumeiser, Philip Loquet
Summary: Comparing early amniocentesis (EA) with mid-trimester amniocentesis (MA), there was no significant difference in procedure-related risk of miscarriage, suggesting that EA may be a safe alternative. Further research is necessary to confirm the findings.
Article
Obstetrics & Gynecology
Jade E. Bilardi, Meredith Temple-Smith
Summary: Miscarriage and recurrent miscarriage have profound and prolonged psychological impacts, yet support for miscarriage remains inadequate. Acknowledgment and validation of grief, provision of information, and addressing the discrepancy between bereavement care offered and desired are important steps to ameliorate the impact. Collecting national miscarriage data and establishing national research funding priorities would allow for a better understanding of the socioeconomic cost and burden of miscarriage and enable targeted research for public health benefit.
FERTILITY AND STERILITY
(2023)
Article
Obstetrics & Gynecology
Moshe Barg, Reut Rotem, Adi Y. Weintraub, Sorina Grisaru-Granovsky, Rachel Michaelson-Cohen, Misgav Rottenstreich
Summary: A national survey in Israel revealed heterogeneity in the management of obstetric anal sphincter injuries (OASIS) following repair, particularly regarding the use of antibiotics. Further studies are needed to examine the consequences of different management protocols.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Tzuria Peled, Eran Ashwal, Reut Rotem, Hen Y. Sela, Sorina Grisaru-Granovsky, Misgav Rottenstreich
Summary: A retrospective cohort study found that unintended uterine extension during cesarean delivery was not associated with an increased risk of uterine scar disruption, but it was associated with uterine scar dehiscence, higher rates of trial of labor after cesarean delivery (TOLAC) failure, and adverse maternal outcome.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Ohad Atia, Ella Hazan, Reut Rotem, Shunit Armon, Simcha Yagel, Sorina Grisaru-Granovsky, Hen Y. Sela, Misgav Rottenstreich
Summary: This study aimed to establish a clinically relevant prediction score for the diagnosis of adnexal torsion (AT) in women who underwent urgent laparoscopy. Using retrospective cohort analysis and machine learning techniques, a predictive score was developed and evaluated for accuracy using ROC curve analysis.
JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
(2023)
Article
Multidisciplinary Sciences
Orna Reichman, Misgav Rottenstreich, Hen Sela, Rachel Michaelson-Cohen, Zvi Ehrlich, Reut Rotem, Sorina Grisaru-Granovsky
Summary: The study aimed to identify risk factors for complicated maternal cesarean delivery (CD) in women undergoing a repeat low-order CD and to develop a predictive model for at-risk women. The results showed that a complicated CD2, Sub-Saharan African origin, and preterm delivery were risk factors for complications in CD3. However, it is difficult to predict which specific women will experience these complications. The sensitivity, specificity, positive predictive value, and negative predictive value of a complicated CD2 for detecting complications in CD3 were 21%, 90%, 30%, and 85%, respectively.
Article
Medicine, General & Internal
Ari Weiss, Hen Y. Sela, Sorina Grisaru-Granovsky, Misgav Rottenstreich
Summary: The objective of this study is to evaluate the maternal and neonatal outcomes of women with short interpregnancy intervals (IPI < 6 months) following a multifetal pregnancy. A multicenter retrospective cohort study was conducted comparing pregnancies with short IPI (<6 months) to those with an IPI of 18-48 months. The primary outcome was the rate of preterm birth (<37 weeks).
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Genetics & Heredity
Naama Srebnik, Tal Margaliot Kalifa, Harry J. J. Hirsch, Fortu Benarroch, Talia Eldar-Geva, Varda Gross-Tsur
Summary: Current guidelines for routine care of women with Prader-Willi syndrome (PWS) do not include recommendations for gynecologic examinations. The authors describe their experience with gynecological examinations in women with PWS and offer recommendations for routine health care for these patients.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
(2023)
Article
Endocrinology & Metabolism
Tzuria Peled, Hen Y. Sela, Ari Weiss, Sorina Grisaru-Granovsky, Misgav Rottenstreich
Summary: This study aimed to investigate whether women with twin gestation and one abnormal value on the 3-hour OGTT are at an increased risk of adverse perinatal outcomes. The study found that women with one abnormal value had higher rates of preterm delivery, large for gestational age neonates, and composite neonatal morbidity. Further research is needed to determine interventions to improve perinatal outcomes in this population.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Article
Medicine, General & Internal
Hila Hochler, Michal Lipschuetz, Yael Suissa-Cohen, Ari Weiss, Hen Y. Sela, Simcha Yagel, Joshua I. Rosenbloom, Sorina Grisaru-Granovsky, Misgav Rottenstreich
Summary: This multicenter retrospective cohort study aimed to examine the impact of maternal age on perinatal outcomes in multiparas. The study found that cesarean delivery rates and NICU admission rates increased as maternal age advanced. The findings highlight the association between advanced maternal age and increased rates of maternal and neonatal complications.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Tzuria Peled, Eyal Lang Ben Nun, Hila Hochler, Hen Y. Sela, Michal Lipschuetz, Ari Weiss, Sorina Grisaru-Granovsky, Misgav Rottenstreich
Summary: This study investigated the impact of the number of previous pregnancy losses on adverse outcomes for nulliparous women and their neonates. The results showed that the risk of preterm delivery and other adverse obstetrical outcomes increased with each additional previous pregnancy loss. Each previous pregnancy loss was associated with a significant, dose-dependent increase in the risk of preterm delivery.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Letter
Obstetrics & Gynecology
Tzuria Peled, Hen Y. Sela, Ari Weiss, Sorina Grisaru-Granovsky, Misgav Rottenstreich
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Meeting Abstract
Obstetrics & Gynecology
Misgav Rottenstreich, Moshe Barg, Ari Weiss, Arnon Samueloff, Hen Sela, Sorina Granovsky Grisaru
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Meeting Abstract
Obstetrics & Gynecology
Ari Weiss, Hen Sela, Moshe Barg, Arnon Samueloff, Sorina Granovsky Grisaru, Misgav Rottenstreich
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Eyal Lang Ben Nun, Hen Y. Sela, Jordanna Joseph, Galit Rudelson, Sorina Grisaru-Granovsky, Misgav Rottenstreich
Summary: Prolonged operative time may serve as a proxy for adverse maternal outcomes, particularly blood products transfusion, in subsequent cesarean delivery among women undergoing repeat cesarean delivery.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Dominique A. Badr, Mieke M. Cannie, Caroline Kadji, Xin Kang, Andrew Carlin, Jacques C. Jani
Summary: The objective of this study was to assess the influence of the test-to-delivery interval on the performance of ultrasound and MRI in predicting birthweight. The results showed that MRI performed best in predicting birthweight greater than gestational age if delivery occurred within two weeks of the examination, with a slight decrease thereafter, while ultrasound performance decreased drastically over time.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2024)
Article
Obstetrics & Gynecology
Corina N. Schoen, Sami Backley, Lauren Orr, Amrita Roy, Tiffany Corlin, Alexander B. Knee
Summary: This retrospective cohort study aimed to evaluate whether induction of labor is associated with a lower risk of cesarean section in patients with isolated polyhydramnios. The study found that planned induction was associated with a lower rate of cesarean delivery compared to expectant management, but the difference was not statistically significant. Additionally, no differences were observed in maternal or fetal secondary outcomes.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2024)
Article
Obstetrics & Gynecology
Ohad Houri, Asaf Romano, Yossi Geron, Gil Zeevi, Eran Hadar, Shiri Barbash-Hazan, Shir Danieli-Gruber
Summary: Women with prior uterine rupture have good maternal and neonatal outcomes in subsequent pregnancies when managed at a tertiary medical center, with planned elective term cesarean delivery, or even earlier, at the onset of spontaneous preterm labor.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2024)
Correction
Obstetrics & Gynecology
Laura E. Janssen, Marjon A. de Boer, Eline C. E. von Konigslow, Elisa Dal, Martijn A. Oudijk, Danielle Robbers-Visser, Christianne J. M. de Groot
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2024)
Review
Obstetrics & Gynecology
Natalia Rzewuska, Jacek Kunicki, Katarzyna Pieniak, Paulina Laskus, Bernadeta Zabielska, Roman Smolarczyk, Michal Kunicki
Summary: This systematic review examined the comorbidity of idiopathic intracranial hypertension (IIH) and polycystic ovarian syndrome (PCOS) and their impact on metabolism, hormone levels, and reproduction. The findings showed a high prevalence of comorbidity between the two conditions, which may have significant clinical implications for patient management.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2024)
