Highly potent dual-targeting angiotensin-converting enzyme 2 (ACE2) and Neuropilin-1 (NRP1) peptides: A promising broad-spectrum therapeutic strategy against SARS-CoV-2 infection

Increased immune escape of the new SARS-CoV-2 variant of concern Omicron

(2022) Jie Hu et al.   Cellular & Molecular Immunology

Application of pseudovirus system in the development of vaccine, antiviral-drugs, and neutralizing antibodies

(2022) Qi Xiang et al.   MICROBIOLOGICAL RESEARCH

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

(2022) Yunlong Cao et al.   NATURE

Highly Potent, Selective, Biostable, and Cell-Permeable Cyclic d-Peptide for Dual-Targeting Therapy of Lung Cancer

(2022) Yunjiang Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural diversity of the SARS-CoV-2 Omicron spike

(2022) Sophie M.-C. Gobeil et al.   MOLECULAR CELL

Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa

(2022) Juliet R. C. Pulliam et al.   SCIENCE

The Omicron subvariant BA.2: Birth of a new challenge during the COVID-19 pandemic

(2022) Farid Rahimi et al.   International Journal of Surgery

Emergence of SARS-CoV-2 Omicron lineages BA.4 and BA.5 in South Africa

(2022) Houriiyah Tegally et al.   NATURE MEDICINE

As Omicron rages on, virus’ path remains unpredictable

(2022) Kai Kupferschmidt   SCIENCE

Non-covalent cyclic peptides simultaneously targeting Mpro and NRP1 are highly effective against Omicron BA.2.75

(2022) Shengnan Yin et al.   Frontiers in Pharmacology

The role of Neuropilin-1 in COVID-19

(2021) Bindu S. Mayi et al.   PLoS Pathogens

SARS-CoV-2 Variants of Concern in the United States—Challenges and Opportunities

(2021) Rochelle P. Walensky et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Establishment of a well-characterized SARS-CoV-2 lentiviral pseudovirus neutralization assay using 293T cells with stable expression of ACE2 and TMPRSS2

(2021) Sabari Nath Neerukonda et al.   PLoS One

Neutralization of SARS-CoV-2 lineage B.1.1.7 pseudovirus by BNT162b2 vaccine–elicited human sera

(2021) Alexander Muik et al.   SCIENCE

SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity

(2021) Seiya Ozono et al.   Nature Communications

Novel Compounds Targeting Neuropilin Receptor 1 with Potential To Interfere with SARS-CoV-2 Virus Entry

(2021) Samantha Perez-Miller et al.   ACS Chemical Neuroscience

SARS-CoV-2 B.1.1.7 and B.1.351 spike variants bind human ACE2 with increased affinity

(2021) Muthukumar Ramanathan et al.   LANCET INFECTIOUS DISEASES

Neutralizing antibodies for the prevention and treatment of COVID-19

(2021) Lanying Du et al.   Cellular & Molecular Immunology

SARS-CoV-2 variants, spike mutations and immune escape

(2021) William T. Harvey et al.   NATURE REVIEWS MICROBIOLOGY

Immune Evasion of SARS-CoV-2 Emerging Variants: What Have We Learnt So Far?

(2021) Ivana Lazarevic et al.   Viruses-Basel

Cellular host factors for SARS-CoV-2 infection

(2021) Jim Baggen et al.   Nature Microbiology

The Role of Neuropilin-1 (NRP-1) in SARS-CoV-2 Infection: Review

(2021) Monika Gudowska-Sawczuk et al.   Journal of Clinical Medicine

Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation

(2021) Lufeng Zheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mechanisms of SARS-CoV-2 entry into cells

(2021) Cody B. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant

(2021) Jun Zhang et al.   SCIENCE

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

(2020) Renhong Yan et al.   SCIENCE

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade

(2020) B. Coutard et al.   ANTIVIRAL RESEARCH

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells

(2020) Markus Hoffmann et al.   MOLECULAR CELL

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Structural basis of receptor recognition by SARS-CoV-2

(2020) Jian Shang et al.   NATURE

Multiorgan and Renal Tropism of SARS-CoV-2

(2020) Victor G. Puelles et al.   NEW ENGLAND JOURNAL OF MEDICINE

TMPRSS2 and COVID-19: Serendipity or Opportunity for Intervention?

(2020) Konrad H. Stopsack et al.   Cancer Discovery

Inhibitors of SARS-CoV-2 Entry: Current and Future Opportunities

(2020) Siyu Xiu et al.   JOURNAL OF MEDICINAL CHEMISTRY

The protein expression profile of ACE2 in human tissues

(2020) Feria Hikmet et al.   Molecular Systems Biology

Can ACE 2 expression explain SARS ‐CoV‐2 infection of the respiratory epithelia in COVID ‐19?

(2020) Martijn C Nawijn et al.   Molecular Systems Biology

COVID-19 update: The race to therapeutic development

(2020) Julianne D. Twomey et al.   DRUG RESISTANCE UPDATES

SARS-CoV-2 vaccines in development

(2020) Florian Krammer   NATURE

Neuropilin-1 is a host factor for SARS-CoV-2 infection

(2020) James L. Daly et al.   SCIENCE

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

(2020) Ludovico Cantuti-Castelvetri et al.   SCIENCE

Honey is cytotoxic towards prostate cancer cells but interacts with the MTT reagent: Considerations for the choice of cell viability assay

(2018) Sean D.A. Abel et al.   FOOD CHEMISTRY

Neuropilin Functions as an Essential Cell Surface Receptor

(2015) Hou-Fu Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration

(2009) T. Teesalu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA