A novel pathogenic variant in MRAP2 in an obese patient with successful outcome of bariatric surgery

Effects of Heterozygous Variants in the Leptin-Melanocortin Pathway on Roux-en-Y Gastric Bypass Outcomes: a 15-Year Case–Control Study

(2022) Alejandro Campos et al.   OBESITY SURGERY

Weight loss specific to indication, remission of diabetes, and short-term complications after sleeve gastrectomy conversion to Roux-en-Y gastric bypass: a systematic review and meta-analysis

(2022) Matyas Fehervari et al.   Surgery for Obesity and Related Diseases

Genetics of Obesity: What We Have Learned Over Decades of Research

(2021) Claude Bouchard   Obesity

Rare genetic causes of obesity: Diagnosis and management in clinical care

(2021) Béatrice Dubern et al.   ANNALES D ENDOCRINOLOGIE

Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension

(2019) Morgane Baron et al.   NATURE MEDICINE

Genetic Obesity and Bariatric Surgery Outcome in 1014 Patients with Morbid Obesity

(2019) M.I. Cooiman et al.   OBESITY SURGERY

MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency

(2018) Karine Clément et al.   NATURE MEDICINE

Weight and Metabolic Outcomes 12 Years after Gastric Bypass

(2017) Ted D. Adams et al.   NEW ENGLAND JOURNAL OF MEDICINE

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

(2016) Nilah M. Ioannidis et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (MC4R) Gene, and Outcomes of Bariatric Operations: A 6-Year Prospective Study

(2016) Amélie Bonnefond et al.   DIABETES CARE

Loss ofMrap2is associated withSim1deficiency and increased circulating cholesterol

(2016) T V Novoselova et al.   JOURNAL OF ENDOCRINOLOGY

Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents

(2016) Emanuele Di Angelantonio et al.   LANCET

The Melanocortin Receptor Accessory Protein 2 promotes food intake through inhibition of the Prokineticin Receptor-1

(2016) Anna L Chaly et al.   eLife

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

From obesity genetics to the future of personalized obesity therapy

(2013) Julia S. El-Sayed Moustafa et al.   Nature Reviews Endocrinology

Melanocortin-4 Receptor Mutations and Polymorphisms Do Not Affect Weight Loss after Bariatric Surgery

(2012) Marion Valette et al.   PLoS One