Article
Biochemistry & Molecular Biology
Laura Basso, Benjamin Boecking, Patrick Neff, Petra Brueggemann, Christopher R. Cederroth, Matthias Rose, Birgit Mazurek
Summary: This study examines comorbidity rates stratified by sex across various conditions and found that women have higher comorbidity rates than men, particularly in terms of mental-physical comorbidity. The most common comorbid diseases in women are musculoskeletal diseases, digestive diseases, and skin diseases, whereas in men they are musculoskeletal diseases, neurological diseases, and digestive diseases. The implications of this study include the importance of integrating mental and physical health care services and shifting clinical care focus towards an individualized, patient-centered approach.
Article
Psychiatry
Xiaoliang Chen, Sheng Zhang, Guoliang Huang, Yan Xu, Qian Li, Jingman Shi, Wenyan Li, Wanxin Wang, Lan Guo, Ciyong Lu
Summary: The study found that five types of child maltreatment and their co-occurrence were associated with an increased risk of depressive symptoms among college students. The effects of emotional abuse, emotional neglect, and the number of maltreatment types on depressive symptoms were stronger for females than for males.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Clinical Neurology
Ziwei Zheng, Wenqing Zhao, Qing Zhou, Yang Yang, Shuangyi Chen, Jun Hu, Wenhui Jiang, Weibo Zhang, Jun Cai, Jianyin Qiu
Summary: This study used a network approach to investigate sex differences in health-promoting lifestyles (HPL) and the cooccurrence symptoms in Shanghai communities. The findings showed that females had significantly higher scores in depressive and anxiety symptoms compared to males, while there were no differences in HPL scores. Restlessness and low energy were identified as central symptoms in the female network, while suicide ideation and restlessness were central in the male network. Physical activity and stress management were found to be the central mental health-promoting behaviors in the female and male network, respectively. However, stress management was positively related to suicide ideation in the male network. It is important for communities to be aware of suicide ideation in males and provide stress management courses, especially for males.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Oncology
Katharina Sies, Julia K. Winkler, Christine Fink, Felicitas Bardehle, Ferdinand Toberer, Timo Buhl, Alexander Enk, Andreas Blum, Wilhelm Stolz, Albert Rosenberger, Holger A. Haenssle
Summary: Advancements in biomedical artificial intelligence may lead to gender biases. This study investigated the sex-related imbalances in training data and diagnostic performance of a market-approved convolutional neural network (CNN) for skin cancer classification. Despite the imbalances in training data, the tested CNN showed comparable performance in classifying skin lesions from female and male patients without any sex-related biases.
EUROPEAN JOURNAL OF CANCER
(2022)
Article
Biochemistry & Molecular Biology
Zhe Pan, Yanhong Chen, Mi Zhou, Tim A. McAllister, Le Luo Guan
Summary: While diversity and composition analysis are common methods for deciphering microbial community differences, they may neglect microbial structural differences driven by interactions. This study found inherent differences in microbial structure between two groups of cattle despite comparable diversity and composition. Group-specific genera intensely interacted with other taxa in the co-occurrence network, highlighting the importance of characterizing microbial networks to identify variations in microbial communities.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2021)
Article
Clinical Neurology
Anna K. Bonkhoff, Andre Karch, Ralph Weber, Juergen Wellmann, Klaus Berger
Summary: The study from a large German stroke registry found that female AIS patients were more likely to receive intraarterial treatment, have a more favorable functional outcome at discharge, and experience lower in-hospital mortality. These results were not influenced by clinical characteristics such as age, premorbid disability, stroke severity, or cause.
Article
Clinical Neurology
Hang Qiu, Liya Wang, Xianrong Zeng, Jingping Pan
Summary: This study investigated the comorbid status of depression among patients with chronic diseases using network analysis. Depressed patients had on average 4 comorbidities, and 84.4% had at least one. The comorbidity network in depression cases was more complex than controls, with intricate but distinct communities present within the network.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Substance Abuse
Emese Kroon, Alessandra Mansueto, Lauren Kuhns, Francesca Filbey, Reinout Wiers, Janna Cousijn
Summary: Background: There is a lack of research on gender differences in cannabis use disorder (CUD) symptomology, despite the increasing use of cannabis in women worldwide. This study aimed to evaluate the CUD symptom network and assess gender differences. The findings showed gender differences in the prevalence of symptoms, but no differences in the symptom networks between men and women. Additionally, there were gender differences in the associations between mood/anxiety disorders and CUD symptoms.
DRUG AND ALCOHOL DEPENDENCE
(2023)
Article
Engineering, Environmental
Hongjun Joo, Myungjin Lee, Jongsung Kim, Jaewon Jung, Jaewon Kwak, Hung Soo Kim
Summary: This study presents a grouping method for stream gauging stations using community detection based on complex networks, which was found to be more effective than cluster analysis in terms of hydrologic similarity, persistence, and connectivity.
STOCHASTIC ENVIRONMENTAL RESEARCH AND RISK ASSESSMENT
(2021)
Article
Mathematics
Attila Mester, Andrei Pop, Bogdan-Eduard-Madalin Mursa, Horea Grebla, Laura Diosan, Camelia Chira
Summary: Evaluation of important nodes in a network can be done through different centrality measures and community detection algorithms, providing overlapping results and complementary information on important nodes.
Article
Psychology, Multidisciplinary
Michaela Junghaenel, Ann-Kathrin Thoene, Christina Dose, Dieter Breuer, Anja Goertz-Dorten, Manfred Doepfner
Summary: The objective of this study is to understand the structure of anxiety and depressive symptoms by using latent factor analysis and network analysis together. The study included 743 children and adolescents seeking outpatient psychotherapy. The results showed a complex relationship between anxiety and depressive symptoms, with stronger associations within each domain than between the two domains. Pain, suicidal thoughts, irritability, and fear of adults were identified as bridge symptoms.
CURRENT PSYCHOLOGY
(2023)
Article
Psychology, Developmental
Xitong Liang, Guanqun Li, Yin He, Chaoying Xu, Xiangzhi Meng, Chunming Lu, Li Liu
Summary: This study investigates the sex differences in the reading-related neural network of Chinese children and its interaction with age. The findings suggest that sex differences in reading neural networks are modulated by age. After controlling for age, boys and girls also show stable sex differences in the relationship between reading neural circuit and reading behavior.
DEVELOPMENTAL COGNITIVE NEUROSCIENCE
(2022)
Article
Nursing
Chiyoung Lee, Xiao Hu
Summary: This study investigated the differences in depressive symptom networks between male and female older adults in a South Korean community. The results showed similar symptom centrality between sexes, but differences in the global and network structure. The female symptom network had stronger edges, particularly in certain connections. Strength centrality did not differ between the two networks.
Article
Cardiac & Cardiovascular Systems
C. Basic, A. Rosengren, U. Dahlstrom, M. Edner, M. Fu, T. Zverkova-Sandstrom, M. Schaufelberger
Summary: This study investigated sex-related differences in early-onset heart failure (HF). The results showed that there were differences between men and women in the incidence and mortality of HF, while long-term mortality was similar between sexes. In addition, women lost more years of life than men.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Microbiology
Jing Zhao, Qing-Bin Lu, Hao Li, Yang Yuan, Ning Cui, Chun Yuan, Xiao-Ai Zhang, Zhen-Dong Yang, Shi-Man Ruan, Lan-Zheng Liu, Juan Du, Li-Qun Fang, Wei Liu
Summary: The study revealed that male SFTS patients had a higher mortality rate compared to females, and were more susceptible to the influence of aging. Older males had a significantly higher risk of death compared to females, and comorbidities were found to have a significant impact on the fatal outcome in female patients.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Psychology, Developmental
Kirstie O'Hare, Aniqa Hussain, Kristin R. Laurens, Gabrielle Hindmarsh, Vaughan J. Carr, Stacy Tzoumakis, Felicity Harris, Melissa J. Green
Summary: Maltreated children are at risk of mental health difficulties, and different levels of contact with child protection services are associated with these difficulties. Early detection and intervention are crucial for children at risk of maltreatment.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Clinical
Melissa J. Green, Patrycja J. Piotroswka, Stacy Tzoumakis, Tyson Whitten, Kristin R. Laurens, Merran Butler, Ilan Katz, Felicity Harris, Vaughan J. Carr
Summary: This study examines factors associated with resilience in children and highlights the importance of individual, familial, and contextual factors in resilience. The findings suggest that resilience processes involve complex interactions and require interagency support.
JOURNAL OF CLINICAL CHILD AND ADOLESCENT PSYCHOLOGY
(2023)
Article
Psychology, Developmental
Wagner Silva Ribeiro, Renee Romeo, Derek King, Shanise Owens, Petra C. Gronholm, Helen L. Fisher, Kristin R. Laurens, Sara Evans-Lacko
Summary: This study examined the influence of stigma, psychopathology, and sociodemographic characteristics on mental health-related service use and costs. The findings suggest that persistent psychopathology, socioeconomic disadvantage, and low caregiver intended stigma-related behavior are associated with increased likelihood of service use among young people, while older age and socioeconomic disadvantage are associated with increased costs.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Developmental
Divya Mehta, Adrian B. Kelly, Kristin R. Laurens, Divna Haslam, Kate E. Williams, Kerryann Walsh, Philip R. A. Baker, Hannah E. Carter, Nigar G. Khawaja, Oksana Zelenko, Ben Mathews
Summary: This review focuses on child maltreatment, highlighting the high prevalence rates and long-term mental health effects. The review also presents five recommendations on measuring trends, studying brain structures and processes, improving teleservices, implementing community-based approaches, and building interdisciplinary alliances.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Correction
Education & Educational Research
Linda J. Graham, Callula Killingly, Kristin R. Laurens, Naomi Sweller
AUSTRALIAN EDUCATIONAL RESEARCHER
(2023)
Review
Psychology, Clinical
Sandra L. Matheson, Mallory Laurie, Kristin R. Laurens
Summary: This study aimed to examine the relationship between psychotic-like experiences (PLEs) and substance use in children and adolescents. The results showed that around two-in-five substance users reported PLEs, while one-in-five with PLEs reported using substances. Substance users were nearly twice as likely to report PLEs than non-users, and those with PLEs were twice as likely to use substances than those without PLEs. Young substance users may represent a subclinical at-risk group for psychosis.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Tiffany P. Gutteridge, Adrian B. Kelly, Kristin R. Laurens
Summary: This study aimed to investigate whether the presence of co-occurring psychopathology symptoms differentiated distressing or impairing psychotic-like experiences (PLEs) among children. The results showed that children with co-occurring internalizing and/or externalizing problems had a higher likelihood of experiencing distressing and/or impairing PLEs compared to children without co-occurring psychopathology. The highest likelihood of distressing and impairing PLEs was observed in children with both internalizing and externalizing comorbidities.
SCHIZOPHRENIA RESEARCH
(2023)
Article
Psychology, Clinical
Kirstie O'Hare, Oliver Watkeys, Johanna C. C. Badcock, Kristin R. R. Laurens, Stacy Tzoumakis, Kimberlie Dean, Felicity Harris, Vaughan J. J. Carr, Melissa J. J. Green
Summary: This study examined the relationship between childhood developmental vulnerabilities and schizotypy in middle childhood, and whether this relationship is mediated by educational underachievement. The results showed that developmental vulnerabilities in early childhood were associated with schizotypy profiles in middle childhood, and educational underachievement played a mediating role in this relationship.
BRITISH JOURNAL OF CLINICAL PSYCHOLOGY
(2023)
Article
Psychiatry
Lauren M. M. Piltz, Emma J. J. Carpendale, Kristin R. R. Laurens
Summary: The current study examined the measurement invariance of the PLEQ-C across different demographic and psychopathology profiles in a community sample of children. The results showed that the PLEQ-C had good invariance across gender, ethnicity, and psychopathology. However, there were some differences in scalar and residual invariance across age groups.
INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH
(2023)
Article
Psychiatry
Kirstie O'Hare, Kristin R. Laurens, Oliver Watkeys, Stacy Tzoumakis, Kimberlie Dean, Felicity Harris, Richard J. Linscott, Vaughan J. Carr, Melissa J. Green
Summary: This study investigates the relationship between different schizotypy risk profiles in childhood and parental mental disorders. The results show that all types of parental mental disorders are associated with childhood schizotypy risk profiles. Children in the true schizotypy group are more likely to have parents with any type of mental disorder.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2023)
Article
Family Studies
Kirstie O'Hare, Stacy Tzoumakis, Oliver Watkeys, Ilan Katz, Kristin R. Laurens, Merran Butler, Felicity Harris, Vaughan J. Carr, Melissa J. Green
Summary: This study examined the associations between characteristics of out-of-home care (OOHC) placements and child protection contact with educational underachievement, mental disorder, and police contact in childhood. The findings showed that placements with foster carers, greater placement instability, longer and more frequent exposure to maltreatment, and longer time spent in care were associated with adverse consequences in all areas. Therefore, children with these placement characteristics should be prioritized for support services.
CHILD ABUSE & NEGLECT
(2023)
Article
Psychology, Developmental
Felicity Harris, Kimberlie Dean, Oliver J. Watkeys, Kristin R. Laurens, Stacy Tzoumakis, Vaughan J. Carr, Melissa J. Green
Summary: Distinct classes of children in the general population are more likely to experience later mental illness and other adverse outcomes based on early childhood developmental vulnerability. If certain risk factors known at the time of birth can reliably predict membership in early childhood risk classes, preventive interventions can be initiated during the earliest years of life. This study examined associations between 14 known risk factors at birth and membership in early childhood risk classes in 66,464 children. The results showed that risk class membership was correlated with maternal mental illness, parental criminal charges, and being male, with unique patterns for certain conditions such as prenatal child protection notification and misconduct risk. These findings suggest that early identification of at-risk children based on birth risk factors can aid in early intervention within the first 2000 days.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Psychology, Multidisciplinary
Adrian B. B. Kelly, Andrew Munnings, Xiang Zhao, Bosco Rowland, Kristin R. R. Laurens, Marilyn Campbell, Joanne Williams, Jen A. A. Bailey, Callula Killingly, Julie Abimanyi-Ochom, Peter Kremer, John W. W. Toumbourou
Summary: This study examined the nature and prevalence of polydrug use in 12-14 year old Australians through three school surveys spanning 11 years. It found that a small proportion of adolescents engaged in wide-ranging polydrug use, with prevalences ranging from 0.44% to 1.78%. Emotional control problems, low academic performance, and poor family management were elevated in the polydrug class.
AUSTRALIAN JOURNAL OF PSYCHOLOGY
(2023)
Article
Psychiatry
Kirstie O'Hare, Oliver Watkeys, Kimberlie Dean, Kristin R. Laurens, Stacy Tzoumakis, Felicity Harris, Vaughan J. Carr, Melissa J. Green
Summary: This study found that schizotypy in childhood can predict mental disorders in adolescence, based on observation of a large population cohort of Australian young people. Three profiles of schizotypy in childhood (true, affective, and introverted) were associated with an increased likelihood of being diagnosed with mental disorders in adolescence.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Psychiatry
Melissa Bradley, Kimberlie Dean, Samsung Lim, Kristin R. Laurens, Felicity Harris, Stacy Tzoumakis, Kirstie O'Hare, Vaughan J. Carr, Melissa J. Green
Summary: This study examines the associations between air pollution exposure at two time-points in early development and psychotic-like experiences (PLEs), and emotional and conduct symptoms in middle childhood. The study found that exposure to nitrogen dioxide (NO2) and particulate matter less than 2.5 μm (PM2.5) during middle childhood is associated with PLEs, but not with emotional symptoms or conduct problems.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2023)
