期刊
CHEMICAL COMMUNICATIONS
卷 51, 期 74, 页码 14119-14122出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc05348j
关键词
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资金
- NIH [5T32EB0011631-10, R01CA166766, K01DK099451, P41EB013598]
- University of California, San Francisco Department of Radiology Seed Grant
- Radiology Society of North America research fellow grant
- SNMMI-ERF William and Mitzi Blahd, MD Pilot Grant
N-(2-Acetamido)-2-aminoethanesulfonic acid (ACES), one of Good's buffers, was applied to pH imaging using hyperpolarized C-13 magnetic resonance spectroscopy. Rapid NMR- and MRI-based pH measurements were obtained by exploiting the sensitive pH-dependence of its C-13 chemical shift within the physiologic range.
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