Article
Clinical Neurology
Hannah Bergwell, Michael P. P. Trevarrow, Elizabeth Heinrichs-Graham, Anna Reelfs, Lauren R. R. Ott, Samantha H. H. Penhale, Tony W. W. Wilson, Max J. J. Kurz
Summary: Cerebral palsy (CP) is a common neurodevelopmental motor disability that causes life-long sensory, perception, and motor impairments. The underlying neurophysiological mechanisms of these impairments worsening during transition from adolescence to adulthood remain poorly understood. Using magnetoencephalographic (MEG) brain imaging, this study found that individuals with CP exhibit altered spontaneous cortical activity during this transition period.
FRONTIERS IN NEUROLOGY
(2023)
Article
Multidisciplinary Sciences
Hyun Joo Cho, Rebecca Waugh, Tianxia Wu, Pattamon Panyakaew, Karin Mente, Demelio Urbano, Mark Hallett, Silvina. G. G. Horovitz
Summary: Sensory trick plays a crucial role in cervical dystonia, and the supplementary motor area (SMA) interacts with other brain regions during sensory trick performance and imagination. The left intraparietal sulcus (IPS) and the SMA-right cerebellum connectivity showed different patterns in CD patients compared to healthy controls.
SCIENTIFIC REPORTS
(2022)
Article
Neurosciences
Ariel D. Roxburgh, David J. White, Brian R. Cornwell
Summary: Anxiety heightens vigilance and stimulus-driven attention, which disrupts cognitive control processes such as response inhibition. This study used magnetoencephalography to investigate the neural mechanisms involved in the relationship between anxiety and stopping during a stop-signal task. The findings suggest that anxiety weakens inhibitory control and that altered functioning of the right inferior frontal gyrus may link impaired cognitive control to heightened stimulus-driven responding in anxiety states.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
Giedre Stripeikyte, Michael Pereira, Giulio Rognini, Jevita Potheegadoo, Olaf Blanke, Nathan Faivre
Summary: This study found that self-generated stimuli are attenuated in numerosity estimations compared to externally generated stimuli, showing a larger underestimation for self-generated words. While the ability to track errors about numerosity estimations was similar across conditions, the linear relationship between reported and actual number of words was stronger for self-generated words. Neuroimaging results revealed increased functional connectivity in specific brain regions during numerosity underestimation for self-generated words.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Biology
Catharina Zich, Andrew J. Quinn, James J. Bonaiuto, George O'Neill, Lydia C. Mardell, Nick S. Ward, Sven Bestmann
Summary: Beta oscillations in the human sensorimotor cortex exhibit burst activity in intermittent periods of high-power, and these bursts are associated with various sensory and motor processes. The precise spatiotemporal structure of beta burst activity remains unclear, but it is suggested that they play a role in information coding and communication. In this study, using magnetoencephalography recordings, we observed that burst activity in the sensorimotor cortex occurs in planar spatiotemporal wave-like patterns along specific anatomical gradients. Furthermore, we found distinct anatomical, spectral, and spatiotemporal characteristics for the two directions of propagation.
Article
Neurosciences
Eric Mooshagian, Eric A. Yttri, Arthur D. Loewy, Lawrence H. Snyder
Summary: The canonical view of motor control states that distal muscles are primarily controlled by the contralateral cerebral hemisphere. However, recent studies have shown that the parietal reach region in the contralateral hemisphere plays a significant role in reach preparation.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Clinical Neurology
Rashelle M. Hoffman, Michael P. Trevarrow, Hannah R. Bergwell, Christine M. Embury, Elizabeth Heinrichs-Graham, Tony W. Wilson, Max J. Kurz
Summary: This study investigated the altered cognition in adults with cerebral palsy using magnetoencephalography (MEG). The results showed that aberrant alpha-beta oscillations during encoding may impact the basic encoding of information in adults with CP, affecting their overall cognition. Weak alpha-beta oscillation within the prefrontal cortex was associated with poorer cognitive performance and higher GMFCS level.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Neurosciences
Fang-Wen Chen, Chun-Hui Li, Bo-Cheng Kuo
Summary: This study investigated the effects of temporal expectations on neural responses and subsequent performance during the retention interval of working memory (WM). The results showed that smaller duration variability and predictable experimental tasks led to greater alpha-power attenuation over the left frontal and parietal regions during WM retention. Moreover, there was a positive relationship between alpha-power attenuation in the left posterior parietal regions and the variability difference in the response benefit. Overall, these findings suggest the importance of temporal expectations in WM maintenance.
Article
Neurosciences
Jonathan Tablante, Lani Krossa, Tannaz Azimi, Lang Chen
Summary: Math learning difficulty (MLD) is a learning disorder characterized by persistent impairments in the understanding and application of numbers independent of intelligence or schooling. This study reviews existing neuroimaging studies to identify the neurobiological basis of MLD and found consistent dysfunction in the right intraparietal sulcus (IPS) and a distributed network of brain regions. The core dysfunction in IPS and the upregulated functions in various brain regions serve as the neurobiological basis of MLD.
HUMAN BRAIN MAPPING
(2023)
Article
Clinical Neurology
Lukas Hensel, Fabian Lange, Caroline Tscherpel, Shivakumar Viswanathan, Jana Freytag, Lukas J. Volz, Simon B. Eickhoff, Gereon R. Fink, Christian Grefkes
Summary: This study assessed the contributions of the ipsilesional and contralesional anterior intraparietal cortex (aIPS) for hand motor function in stroke patients and found increased resting-state connectivity in patients with good motor outcome. Interhemispheric connectivity was also found to be correlated with better motor performance.
Article
Neurosciences
Maggie P. Rempe, Brandon J. Lew, Christine M. Embury, Nicholas J. Christopher-Hayes, Mikki Schantell, Tony W. Wilson
Summary: This study found that spontaneous beta power increases with age in the sensorimotor cortices, with no clear association between cortical thickness and spontaneous beta power. In the sensorimotor regions, cortical thickness and spontaneous beta power each uniquely contribute to the prediction of motor function when controlling for age.
Article
Neurosciences
Melissa Newton, Savannah L. Cookson, Mark D'Esposito, Andrew S. Kayser
Summary: The study indicates that subregions within the intraparietal sulcus (IPS) exhibit activity responsive to abstract decision-making, and it suggests that IPS may be organized into frontoparietal subnetworks that support hierarchical cognitive control.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
George Zacharopoulos, Roi Kadosh Cohen
Summary: Working memory capacity is crucial for cognition, with persistent activity in parietal and frontal regions playing key roles. Glutamate in the left intraparietal sulcus positively correlates with WM capacity, while parieto-cingulate connectivity negatively correlates with WM capacity, mediating the relationship between glutamate concentration and WM capacity.
Article
Neurosciences
Nathan M. Petro, Lauren R. Ott, Samantha H. Penhale, Maggie P. Rempe, Christine M. Embury, Giorgia Picci, Yu-Ping Wang, Julia M. Stephen, Vince D. Calhoun, Tony W. Wilson
Summary: This study used MEG to record brain activity in typically developing youth during eyes-open and eyes-closed rest. The results showed that eyes-open condition had stronger neural activity, especially in the visual cortex. Additionally, the theta power in the frontal cortex became stronger with increasing age in the eyes-open condition. There were no differences observed between males and females.
Article
Neurosciences
Ana Arsenovic, Anja Ischebeck, Natalia Zaretskaya
Summary: This study found that different regions of the human visual system respond to illusory shapes, with the intraparietal sulcus areas showing a preference towards contralateral shapes. Additionally, as task difficulty increased, anterior areas displayed response attenuation. The research suggests that the intraparietal sulcus can represent illusory content generated not only by moving stimuli, but also by stationary stimuli.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Psychology, Biological
Ariel D. Roxburgh, Matthew E. Hughes, Brian R. Cornwell
BIOLOGICAL PSYCHOLOGY
(2019)
Article
Neurosciences
Ariel D. Roxburgh, David J. White, Brian R. Cornwell
Summary: Anxiety heightens vigilance and stimulus-driven attention, which disrupts cognitive control processes such as response inhibition. This study used magnetoencephalography to investigate the neural mechanisms involved in the relationship between anxiety and stopping during a stop-signal task. The findings suggest that anxiety weakens inhibitory control and that altered functioning of the right inferior frontal gyrus may link impaired cognitive control to heightened stimulus-driven responding in anxiety states.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Article
Substance Abuse
A. D. Roxburgh, D. Best, D. I. Lubman, V. Manning
Summary: The study found that diversity in the social network is associated with recovery strengths in early recovery, while the number of close people in the network is more important in stable recovery.
ADDICTION RESEARCH & THEORY
(2023)