Article
Biochemistry & Molecular Biology
Algirdas Zalimas, Raimonda Kubiliute, Kristina Zukauskaite, Rasa Sabaliauskaite, Mantas Trakymas, Simona Letautiene, Edita Miseikyte Kaubriene, Jurgita Usinskiene, Albertas Ulys, Sonata Jarmalaite
Summary: Active surveillance is the best strategy for managing small renal masses, but reliable methods for early detection and disease aggressiveness prediction are urgently needed. This study validates DNA methylation biomarkers for non-invasive detection and prognosis of small renal masses.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Cardiac & Cardiovascular Systems
Victor J. M. Zeijen, Lida Feyz, Rajiv Nannan Panday, Kevin Veen, Jorie Versmissen, Isabella Kardys, Nicolas M. Van Mieghem, Joost Daemen
Summary: This study found that renal denervation can safely maintain long-term blood pressure-lowering effects for at least five years, with stable antihypertensive drug usage over time.
CLINICAL RESEARCH IN CARDIOLOGY
(2022)
Article
Acoustics
Richard G. G. Barr, Angelo Cestone, Cynthia Peterson, Annalisa De Silvestri
Summary: The purpose of this study was to determine the natural history and necessity of long-term follow-up for renal masses that do not show enhancement on contrast-enhanced ultrasound (CEUS). The results of the study showed that all renal masses without enhancement on CEUS can be classified as benign.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Article
Urology & Nephrology
Steven C. Campbell, Peter E. Clark, Sam S. Chang, Jose A. Karam, Lesley Souter, Robert G. Uzzo
Summary: Significant progress has been made in the evaluation and management of clinically-localized renal masses. These guidelines offer updated, evidence-based recommendations on evaluation and counseling, highlighting the evolving role of renal-mass-biopsy (RMB).
JOURNAL OF UROLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Christiaan V. Widdershoven, Brigitte M. Aarts, Patricia J. Zondervan, Michael M. E. L. Henderickx, Elisabeth G. Klompenhouwer, Otto M. van Delden, Warner Prevoo, Alexander D. Montauban van Swijndregt, Reindert J. A. van Moorselaar, Axel Bex, Brunolf W. Lagerveld
Summary: This study highlights the importance of obtaining a biopsy prior to the ablation procedure in a separate session to reduce the rate of potentially unnecessary ablations.
ABDOMINAL RADIOLOGY
(2021)
Article
Surgery
Patrick J. O'Dwyer, Cindy Chew, Samer Zino, Michael G. Serpell
Summary: This study demonstrates that the long-term oncological outcomes of laparoscopic surgery for patients with phaeochromocytoma are at least equivalent to that of open surgery. The study conducted a follow-up on a consecutive series of patients and found low recurrence rate, no local recurrence, and high long-term disease-free survival rate with laparoscopic surgery.
Article
Oncology
Hideaki Yahata, Keisuke Kodama, Kaoru Okugawa, Kazuhisa Hachisuga, Nobuko Yasutake, Shoji Maenohara, Hiroshi Yagi, Masafumi Yasunaga, Tatsuhiro Ohgami, Ichiro Onoyama, Kazuo Asanoma, Hiroaki Kobayashi, Kenzo Sonoda, Shingo Baba, Kousei Ishigami, Yoshihiro Ohishi, Yoshinao Oda, Kiyoko Kato
Summary: The long-term outcome and complications of sentinel node biopsy (SNB) in patients with early-stage cervical cancer who underwent hysterectomy or trachelectomy were evaluated in this study. The results showed that SNB for early-stage cervical cancer might be safe and effective, with a low recurrence rate and postoperative complications.
GYNECOLOGIC ONCOLOGY
(2022)
Article
Biology
Angyalka Valik, Katalin Harangozo, Andras Garami, Zsolt Juhasz, Gergo Jozsa, Aba Lorincz
Summary: This study assessed the graft and donor areas of children who underwent autologous skin transplantation using two assessment scales. The results showed significant differences between parents and examiners in their perception of the children's scars. Medical professionals rated the donor site more positively than the transplanted area, highlighting the importance of evaluating the effectiveness and improvement techniques of autologous skin grafting.
Article
Endocrinology & Metabolism
Dianna L. Ng, Annemieke van Zante, Ann Griffin, Nancy K. Hills, Britt-Marie Ljung
Summary: This study retrospectively reviewed the UCSF pathology database for thyroid FNABs, analyzing a large cohort of patients with long-term follow-up to determine the risk of thyroid malignancy for different diagnostic categories. The results showed that patients with initial benign or unsatisfactory biopsy results are unlikely to develop thyroid malignancy or die of thyroid cancer, highlighting the high accuracy of FNAB in detecting malignancy.
Article
Infectious Diseases
Jintao Zhang, Jiawei Xu, Shengyu Zhou, Chunting Wang, Ximing Wang, Wei Zhang, Kang Ning, Yun Pan, Tian Liu, Jiping Zhao, Liang Dong
Summary: A study of 527 discharged COVID-19 patients found that approximately 6.1% showed re-detectable positive status, with juvenile patients being more susceptible to infection recurrence. Antibody detections at 3 and 6 months post-discharge were 14.2% and 25.0% respectively, with cases of negative antibodies more common among juvenile patients. These findings have implications for long-term management of recovered COVID-19 patients.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Orthopedics
Andrew E. Jimenez, James D. Fox, Peter F. Monahan, Michael S. Lee, Tom George, David R. Maldonado, Benjamin R. Saks, Ajay C. Lall, Benjamin G. Domb
Summary: High BMI does not adversely affect the outcomes of high-level athletes undergoing hip arthroscopy for FAIS. They show significant improvement in patient-reported outcomes and comparable rates of achieving clinically meaningful improvement compared to athletes with a normal BMI after at least 2 years.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2022)
Article
Oncology
Lena Nemitz, Anna Vincke, Bianca Michalik, Svenja Engels, Luca-Marie Meyer, Rolf-Peter Henke, Friedhelm Wawroschek, Alexander Winter
Summary: The current study suggests that the radioisotope-guided DSNB procedure may reduce the complication rate of inguinal lymphadenectomy in patients with cN0 penile cancer. However, DSNB and penile surgery should be performed simultaneously to minimize the false-negative rate.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Emanuele Zarba Meli, Anna De Santis, Giuliana Cortese, Elena Manna, Tiziana Mastropietro, Massimo La Pinta, Andrea Loreti, Floriana Arelli, Paola Scavina, Mauro Minelli, Angela Damiana Andrulli, Leopoldo Costarelli, Laura Broglia, Tatiana Ponzani, Lucio Fortunato
Summary: Nipple-sparing mastectomy (NSM) is a safe option for breast cancer patients, even after neoadjuvant chemotherapy (NACT), with good cosmetic results and comparable complications to primary surgery. Tumor stage and age are independent factors for local relapse. The study confirms the efficacy of NSM after NACT.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Obstetrics & Gynecology
Aude Braye, Susanne Bohler, Veerle Vloeberghs, Veerle De Boe, Jean De Schepper, Inge Gies, Ellen Goossens
Summary: This study investigated whether early-diagnosed Klinefelter syndrome patients were offered cryopreservation of testicular tissue for fertility preservation before spermatogonial stem cell loss, and whether these patients had behavioral, cognitive, and psychological problems. The results showed that psychological problems may influence the decision of Klinefelter syndrome patients to undergo fertility preservation. Additionally, it was found that harvesting testicular tissue did not have a long-term impact on the gonadal development of Klinefelter syndrome patients.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Multidisciplinary Sciences
Yoshio Sakai, Alessandro Nasti, Yumie Takeshita, Miki Okumura, Shinji Kitajima, Masao Honda, Takashi Wada, Seiji Nakamura, Toshinari Takamura, Takuro Tamura, Kenichi Matsubara, Shuichi Kaneko
Summary: This study examined gene expression profiles of whole blood from 61 individuals every 4 years for 8 years, revealing that genes related to immune system pathways were very stable, while genes involved in cellular machinery pathways were more prone to alterations. The study demonstrates that gene expression profiles of whole blood can reveal physiological changes over time.
SCIENTIFIC REPORTS
(2021)