Pharmacogenomics and adverse effects of anti‐infective drugs in children

Evaluation of voriconazole related adverse events in pediatric patients with hematological malignancies

(2022) Ozge Ertem et al.   JOURNAL OF ONCOLOGY PHARMACY PRACTICE

Genetic testing of UGT1A1 in the diagnosis of Gilbert syndrome: The discovery of seven novel variants in the Chinese population

(2022) Leilei Gu et al.   Molecular Genetics & Genomic Medicine

Association Between Expanded Genomic Sequencing Combined With Hearing Screening and Detection of Hearing Loss Among Newborns in a Neonatal Intensive Care Unit

(2022) Yunqian Zhu et al.   JAMA Network Open

Neuropsychiatric Adverse Events During 12 Months of Treatment With Efavirenz in Treatment-Naïve HIV-Infected Patients in China: A Prospective Cohort Study

(2021) Wei Hua et al.   Frontiers in Psychiatry

Pharmacogenetic Associations Between Atazanavir/UGT1A1*28 and Efavirenz/rs3745274 (CYP2B6) Account for Specific Adverse Reactions in Chilean Patients Undergoing Antiretroviral Therapy

(2021) Daniela Poblete et al.   Frontiers in Pharmacology

Application of a Physiologically Based Pharmacokinetic Model to Characterize Time-dependent Metabolism of Voriconazole in Children and Support Dose Optimization

(2021) Yahui Zhang et al.   Frontiers in Pharmacology

Pharmacogenetics of the Late-Onset Efavirenz Neurotoxicity Syndrome (LENS)

(2021) Roland van Rensburg et al.   CLINICAL INFECTIOUS DISEASES

Factors Affecting Voriconazole Trough Concentration and Optimal Maintenance Voriconazole Dose in Chinese Children

(2021) Yi-Chang Zhao et al.   Antibiotics-Basel

Retrospective review of drug‐induced Stevens‐Johnson syndrome and toxic epidermal necrolysis cases at a pediatric tertiary care institution

(2020) Cathryn Sibbald et al.   PEDIATRIC DERMATOLOGY

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

Descriptive study of adverse drug reactions in a tertiary care pediatric hospital in México from 2014 to 2017

(2020) Olga Morales-Ríos et al.   PLoS One

A 7-Years Active Pharmacovigilance Study of Adverse Drug Reactions Causing Children Admission to a Pediatric Emergency Department in Sicily

(2020) Chiara Nasso et al.   Frontiers in Pharmacology

Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy

(2020) Kristi Krebs et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cohort study on Adverse Drug Reactions in adults admitted to the medical wards of a tertiary hospital in Nigeria: Prevalence, incidence, risk factors and fatality

(2020) Aduragbenro D.A. Adedapo et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Drug-induced injury due to flucloxacillin: relevance of multiple HLA alleles

(2019) Paola Nicoletti et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

HLA-B*57:01 screening and hypersensitivity reaction to abacavir between 1999 and 2016 in the OPERA® observational database: a cohort study

(2019) Karam Mounzer et al.   AIDS Research and Therapy

Frequency of the CYP2C19*17 polymorphism in a Chilean population and its effect on voriconazole plasma concentration in immunocompromised children

(2019) N. Espinoza et al.   Scientific Reports

Adverse Drug Event–Related Admissions to a Pediatric Emergency Unit

(2018) Indira Valadê Carvalho et al.   PEDIATRIC EMERGENCY CARE

Pharmacogenetics and pharmacokinetics of CNS penetration of efavirenz and its metabolites

(2018) Eric H Decloedt et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

UGT1A1 genotypes and unconjugated hyperbilirubinemia phenotypes in post-neonatal Chinese children

(2018) Kuerbanjiang Abuduxikuer et al.   MEDICINE

Cytochrome 2B6 polymorphism and efavirenz-induced central nervous system symptoms : a substudy of the ANRS ALIZE trial

(2017) S Gallien et al.   HIV MEDICINE

The first reported case of concurrent trimethoprim-sulfamethoxazole-induced immune hemolytic anemia and thrombocytopenia

(2017) Yevgeniy A. Linnik et al.   TRANSFUSION

The impact of genetic polymorphisms on the pharmacokinetics of efavirenz in African children

(2016) Andrzej Bienczak et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Antibiotic-Induced Liver Injury in Paediatric Outpatients: A Case-Control Study in Primary Care Databases

(2016) Carmen Ferrajolo et al.   DRUG SAFETY

Voriconazole dosing and therapeutic drug monitoring in children: experience from a paediatric tertiary care centre

(2016) Alison Boast et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Adverse events associated with abacavir use in HIV-infected children and adolescents: a systematic review and meta-analysis

(2016) Julie Jesson et al.   Lancet HIV

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline forUGT1A1and Atazanavir Prescribing

(2015) RS Gammal et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacogenetics of abacavir hypersensitivity: A systematic review and meta-analysis of the association with HLA-B*57:01

(2015) Bernardo Sousa-Pinto et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Adverse Event Detection and Labeling in Pediatric Drug Development

(2015) Jeremiah D. Momper et al.   Therapeutic Innovation & Regulatory Science

Pharmacokinetics and Safety of Voriconazole Intravenous-to-Oral Switch Regimens in Immunocompromised Japanese Pediatric Patients

(2014) Masaaki Mori et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mitochondrial mutation m.1555A>G as a risk factor for failed newborn hearing screening in a large cohort of preterm infants

(2014) Wolfgang Göpel et al.   BMC Pediatrics

The role of genetic polymorphisms in cytochrome P450 and effects of tuberculosis co-treatment on the predictive value of CYP2B6 SNPs and on efavirenz plasma levels in adult HIV patients

(2013) Emile Bienvenu et al.   ANTIVIRAL RESEARCH

Correlation of CYP2C19 Phenotype With Voriconazole Plasma Concentration in Children

(2013) Atsushi Narita et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Impact of UGT1A1 Gilbert Variant on Discontinuation of Ritonavir-Boosted Atazanavir in AIDS Clinical Trials Group Study A5202

(2012) Heather J. Ribaudo, Eric S. Daar, Camlin Tierney, Gene D. Morse, Katie Mollan, Paul E. Sax, Margaret A. Fischl, Ann C. Collier, David W. Haas et al.   JOURNAL OF INFECTIOUS DISEASES

Prevalence of HLA-B*5701 among HIV-Infected Children in Thailand and Cambodia

(2012) Thanyawee Puthanakit et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Short Communication: UGT1A1*28 Variant Allele Is a Predictor of Severe Hyperbilirubinemia in HIV-Infected Patients on HAART in Southern Brazil

(2011) Lisiane Turatti et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450-2C19 (CYP2C19) Genotype and Clopidogrel Therapy

(2011) S A Scott et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Investigation of mitochondrial sequence variants associated with aminoglycoside-induced ototoxicity in South African TB patients on aminoglycosides

(2010) Hanniqué Human et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mutation analysis of mitochondrial 12S rRNA gene in Polish patients with non-syndromic and aminoglycoside-induced hearing loss

(2010) Małgorzata Rydzanicz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genetic Factors Influencing Severe Atazanavir‐Associated Hyperbilirubinemia in a Population with Low UDP‐Glucuronosyltransferase 1A1*28 Allele Frequency

(2010) Wan Beom Park et al.   CLINICAL INFECTIOUS DISEASES

Genome-wide association of serum bilirubin levels in Korean population

(2010) Tae-Wook Kang et al.   HUMAN MOLECULAR GENETICS

Mitochondrial 12S rRNA variants in 1642 Han Chinese pediatric subjects with aminoglycoside-induced and nonsyndromic hearing loss

(2010) Jianxin Lu et al.   MITOCHONDRION

Mitochondrial 12S rRNA mutations associated with aminoglycoside ototoxicity

(2010) Min-Xin Guan   MITOCHONDRION

Genetic mutations and aminoglycoside-induced ototoxicity in neonates

(2010) Romaine F. Johnson et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

Occurrence of Acute Otitis Media During Colds in Children Younger Than Four Years

(2010) Carlos Eladio Armengol et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Correlation between voriconazole trough plasma concentration and hepatotoxicity in patients with different CYP2C19 genotypes

(2009) Kazuaki Matsumoto et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Mitochondrial haplotype and phenotype of 13 Chinese families may suggest multi-original evolution of mitochondrial C1494T mutation

(2009) Yuhua Zhu et al.   MITOCHONDRION

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

High Sensitivity of Human Leukocyte Antigen–B*5701 as a Marker for Immunologically Confirmed Abacavir Hypersensitivity in White and Black Patients

(2008) Michael Saag et al.   CLINICAL INFECTIOUS DISEASES