Jisha Mary Thomas, Pitchavel Vidhyapriya, Akhil K. Sivan, Natarajan Sakthivel, Chinnappan Sivasankar
Summary: Two series of manganese(I) tricarbonyl complexes containing different ligands have been synthesized and their CO-releasing ability and anticancer activity have been studied. The synthesized complexes have been characterized and their MnCO bond strength and cytotoxicity have been investigated. Some of the complexes show potential application towards lung cancer cells under visible light activation.
Anton Iemtsev, Fatima Hassouna, Martin Klajmon, Alex Mathers, Michal Fulem
Summary: This study evaluates the compatibility between biodegradable polyesters and active pharmaceutical ingredients (APIs) and investigates the physical stability of drug carriers using phase diagrams. The results show varying levels of compatibility between different ratios of PLGA and model APIs, with only the IND-PLGA75 formulation remaining stable after storage.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2022)