Article
Obstetrics & Gynecology
Ana-Maria Iancu, Ally Murji, Ovina Chow, Jodi Shapiro, Amanda Cipolla, Lindsay Shirreff
Summary: This study retrospectively reviewed hysterectomies conducted in Ontario, Canada from 2016 to 2019 to evaluate the proportion of justified BSO and determine the prevalence of avoidable BSO. The findings showed that most BSOs were justified based on pathologic diagnosis, with endometrial cancer being the most common indication. However, 5.6% of BSOs were considered avoidable, highlighting the need for standardized practice in BSO.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2022)
Article
Obstetrics & Gynecology
Jellena Wong, Ally Murji, Zahra Sunderji, Ovina Chow, Jodi Shapiro, Wendy Wolfman, Lindsay Shirreff
Summary: This study aimed to examine predictors of concurrent bilateral salpingo-oophorectomy at hysterectomy and found that in some cases, this procedure may not be necessary, with 8% of patients potentially being able to preserve their ovaries. Procedures performed by fellowship-trained surgeons were more likely to have preoperative indications.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2021)
Article
Oncology
Martha Hickey, Katrina M. Moss, Alison Brand, C. David Wrede, Susan M. Domchek, Bettina Meiser, Gita D. Mishra, Hadine Joffe
Summary: Risk-reducing bilateral salpingo-oophorectomy significantly reduces ovarian cancer risk in women, but it also leads to a rapid increase in clinically significant depressive and anxiety symptoms, despite hormone therapy use.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Oncology
Sudheer R. Vemuru, Michael Bronsert, Kristen Vossler, Victoria D. Huynh, Laurel Beaty, Gretchen Ahrendt, Jaime Arruda, Christodoulos Kaoutzanis, Kristin E. Rojas, Laura Bozzuto, Simon Kim, Sarah E. Tevis
Summary: This study compared postoperative complication rates and healthcare charges between patients who underwent coordinated versus staged breast surgery and bilateral salpingo-oophorectomy (BSO). The results showed that the coordinated group had a higher incidence of postoperative complications, while the costs were similar. These data can help high-risk patients make informed decisions.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Martha Hickey, Katrina M. Moss, Gita D. Mishra, Efrosinia O. Krejany, Susan M. Domchek, John D. Wark, Alison Trainer, Robert A. Wild
Summary: The study aimed to compare cardiometabolic risk 12 months after RRBSO in premenopausal women with a control group and analyze the effects of Hormone Therapy (HT) on cardiometabolic risk. The results showed that while there were some significant increases in weight and waist circumference post-RRBSO, these differences were not significant when adjusted for baseline values. Additionally, the study found that HT after RRBSO may help to prevent an increase in waist circumference, with a greater increase observed in non-HT users compared to HT users.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Obstetrics & Gynecology
Marjolein Hermens, Anne M. van Altena, Johan Bulten, Huib A. A. M. van Vliet, Albert G. Siebers, Ruud L. M. Bekkers
Summary: In this retrospective cohort study, researchers found a significant reduction in ovarian cancer incidence in women with histologically proven endometriosis after bilateral salpingooophorectomy (BSO). The results suggest that endometriosis surgery could be a preventive strategy for ovarian cancer in high-risk women with endometriosis.
FERTILITY AND STERILITY
(2022)
Article
Medicine, General & Internal
Maria C. Cusimano, Maria Chiu, Sarah E. Ferguson, Rahim Moineddin, Suriya Aktar, Ning Liu, Nancy N. Baxter
Summary: This study found that bilateral salpingo-oophorectomy in women undergoing non-malignant hysterectomy was associated with increased all cause mortality, particularly in younger women. However, this surgical procedure did not have a detrimental effect on survival in postmenopausal women.
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Article
Obstetrics & Gynecology
Lara Terra, Philippe R. Lee Meeuw Kjoe, Joost A. Agelink van Rentergem, Maarten J. Beekman, Bernadette A. M. Heemskerk-Gerritsen, Marc van Beurden, Jeanine E. Roeters van Lennep, Helena C. van Doorn, Joanna A. de Hullu, Marian J. E. Mourits, Eleonora B. L. van Dorst, Constantijne H. Mom, Brigitte F. M. Slangen, Katja N. Gaarenstroom, Lizet E. van Der Kolk, J. Margriet Collee, Marijke R. Wevers, Margreet G. E. M. Ausems, Klaartje van Engelen, Irma van de Beek, Lieke P. V. Berger, Christi J. van Asperen, Encarna B. Gomez Garcia, Angela H. E. M. Maas, Maartje J. Hooning, Elsken van Der Wall, Flora E. van Leeuwen, Sanne B. Schagen
Summary: This study aimed to examine the effect of a premenopausal risk-reducing salpingo-oophorectomy (RRSO) on objective and subjective cognition in women at increased risk of ovarian cancer. The results indicated that there was no association between premenopausal RRSO and objective cognition, but women with a premenopausal RRSO reported more problems with reasoning and multitasking compared to women with a postmenopausal RRSO.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Neurosciences
Alberto Fernandez-Pena, Francisco J. Navas-Sanchez, Daniel Martin de Blas, Luis Marcos-Vidal, Manuel Desco, Susanna Carmona
Summary: Surgical menopause causes cortical atrophy, while parity may mitigate the impact.
HUMAN BRAIN MAPPING
(2023)
Article
Obstetrics & Gynecology
Micaela Sundell, Jan Brynhildsen, Mats Fredrikson, Mikael Hoffmann, Anna-Clara Spetz Holm
Summary: This retrospective cohort study in Sweden investigated the use of menopausal hormone therapy (MHT) in premenopausal women after bilateral oophorectomy. The study found that only 69% of women without malignancy underwent MHT within 1 year after surgery, and the duration of treatment was limited. The authors suggest further research is needed to understand the reasons behind the low dispensation rate in this group and improve adherence to treatment guidelines.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Oncology
Damiano Gentile, Agnese Losurdo, Andrea Sagona, Monica Zuradelli, Wolfgang Gatzemeier, Erika Barbieri, Alberto Testori, Valentina Errico, Paolo Bianchi, Ersilia Biondi, Rosalba Torrisi, Armando Santoro, Corrado Tinterri
Summary: This study compared the oncological outcomes of BRCA-mutation carriers treated with breast-conserving therapy (BCT) or mastectomy. It also analyzed the role of bilateral salpingo-oophorectomy (BSO) and identified independent predictive factors for BC treatment. The results showed that there was no significant difference in disease-free survival (DFS), distant disease-free survival (DDFS), and overall survival (OS) between patients treated with BCT or mastectomy. Patients treated with BSO had better DDFS and OS compared to ovarian conservation. Three predictive factors for BCT were identified: age <= 41 years, genetic testing performed post-operatively, and breast tumors <= 21 mm.
Review
Oncology
India Hickey, Swati Jha, Lynda Wyld
Summary: This study explored the psychosexual impacts of risk-reducing bilateral salpingo-oophorectomy, with results indicating that women undergoing the surgery often feel unprepared for the psychological and sexual side effects. RRBSO was found to commonly cause distress and problems for women and their partners.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Oncology
Martha Hickey, Katrina M. Moss, Efrosinia O. Krejany, C. David Wrede, Susan M. Domchek, Judy Kirk, Alison Brand, Alison Trainer, Gita D. Mishra, Fiona C. Baker
Summary: Sleep quality may be affected after risk-reducing salpingo-oophorectomy (RRSO), especially with a higher incidence of new onset sleep disturbance. Risk factors for this sleep disturbance include severe vasomotor symptoms, obesity, and smoking.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Oncology
Paige E. Tucker, Paul A. Cohen, Max K. Bulsara, Stephanie Jeffares, Christobel Saunders
Summary: The study found that whether breast cancer survivors had undergone bilateral salpingo-oophorectomy did not significantly impact their sexual function and quality of life, with similar scores reported in both groups.
SUPPORTIVE CARE IN CANCER
(2021)
Review
Obstetrics & Gynecology
Denise R. Nebgen, Susan M. Domchek, Joanne Kotsopoulos, Joanne A. de Hullu, Emma J. Crosbie, Vincent Singh Paramanandam, Monique Brood van Zanten, Barbara M. Norquist, Theresa Guise, Serge Rozenberg, Allison W. Kurian, Holly J. Pederson, Nese Yuksel, Rachel Michaelson-Cohen, Sharon L. Bober, Agnaldo Lopes da Silva, Nora Johansen, F. Guidozzi, D. Gareth Evans, Usha Menon, Sheryl A. Kingsberg, C. Bethan Powell, Giovanni Grandi, Claudia Marchetti, Michelle Jacobson, Donal J. Brennan, Martha Hickey
Summary: Women with high inherited risk of ovarian cancer can undergo risk-reducing salpingo-oophorectomy (RRSO) between the ages of 35 and 45. While RRSO can save lives, it can also cause symptoms that negatively impact quality of life and long-term health. This scoping review explores the effects of RRSO on short- and long-term health and provides evidence-based international consensus recommendations for comprehensive care.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Endocrinology & Metabolism
Maylyn Goh, Hanh H. Nguyen, Nadia N. Khan, Frances Milat, Jacqueline A. Boy, Amanda J. Vincent
CLINICAL ENDOCRINOLOGY
(2019)
Article
Geriatrics & Gerontology
Velislava Kiriakova, Shamil D. Cooray, Ladan Yeganeh, Gowri Somarajah, Frances Milat, Amanda J. Vincent
Article
Medicine, General & Internal
Mathis Grossmann, Sabashini K. Ramchand, Frances Milat, Amanda Vincent, Elgene Lim, Mark A. Kotowicz, Jill Hicks, Helena J. Teede
MEDICAL JOURNAL OF AUSTRALIA
(2019)
Article
Obstetrics & Gynecology
L. Yeganeh, J. A. Boyle, M. Gibson-Helm, H. Teede, A. J. Vincent
Review
Obstetrics & Gynecology
N. Panay, R. A. Anderson, R. E. Nappi, A. J. Vincent, S. Vujovic, L. Webber, W. Wolfman
Article
Obstetrics & Gynecology
Rinky Giri, Amanda J. Vincent
Summary: Premature ovarian insufficiency and early menopause can have significant adverse health impacts on women, with a higher prevalence than previously thought. Various biopsychosocial risk factors are associated with these conditions, but establishing causal roles and underlying mechanisms remains challenging. Further understanding and clarification of these risk factors will help in developing prevention and risk minimization strategies to optimize women's health.
SEMINARS IN REPRODUCTIVE MEDICINE
(2020)
Review
Obstetrics & Gynecology
H. H. Nguyen, F. Milat, A. J. Vincent
Summary: Premature ovarian insufficiency (POI) can lead to musculoskeletal complications such as osteoporosis and fractures, which have a significant impact on women. The decline in muscle mass may exacerbate skeletal fragility, but has not been thoroughly studied in women with POI.
Letter
Endocrinology & Metabolism
Alicia R. Jones, Peter R. Ebeling, Helena Teede, Frances Milat, Amanda J. Vincent
CLINICAL ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
S. L. Kozica-Olenski, B. Garth, J. A. Boyle, A. J. Vincent
Summary: This study explored the experiences and acceptability of telehealth use for women and clinicians within a specialized menopause service during the COVID-19 pandemic. The majority of participants perceived telehealth as an acceptable way to deliver menopause care, citing benefits such as convenience, greater access to care, and improved safety. However, challenges included concerns about personalized quality of care and logistical issues. A hybrid flexible delivery model combining telehealth and face-to-face care was recommended, along with improvements to support the integration of telehealth into routine care.
Article
Orthopedics
Udari N. Colombage, Sze-Ee Soh, Kuan-Yin Lin, Michelle White, Amanda Vincent, Jane Fox, Helena C. Frawley
Summary: Breast cancer treatments may result in pelvic floor dysfunction, particularly urinary incontinence. Women with breast cancer have a higher occurrence of urinary incontinence and experience a greater impact of urinary symptoms compared to those without breast cancer.
BRAZILIAN JOURNAL OF PHYSICAL THERAPY
(2022)
Article
Obstetrics & Gynecology
Samantha L. Kozica-Olenski, Drishti P. Ghelani, Jacqueline A. Boyle, Amanda J. Vincent
Summary: The COVID-19 pandemic led to significant changes in menopause service delivery, with a shift from in-person consultations to telehealth. Telehealth was perceived as feasible and acceptable by women, and a hybrid service delivery model incorporating both telehealth and face-to-face consultations was favored. The majority of women viewed the continuation of telehealth consultations as useful post-pandemic.
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
(2023)
Review
Obstetrics & Gynecology
S. Bontempo, L. Yeganeh, R. Giri, A. J. Vincent
Summary: This systematic review evaluates the impact of menopausal hormone therapy (MHT) on cardiovascular outcomes and risk factors in postmenopausal women with cardiovascular disease (CVD). The findings indicate that MHT does not provide any benefit for secondary CVD prevention and its effects on cardiac risk factors vary.
Review
Medicine, General & Internal
Alicia R. Jones, Madhuni Herath, Peter R. Ebeling, Helena Teede, Amanda J. Vincent
Summary: This study summarized models of care for osteoporosis and described implementation characteristics and evidence for improving outcomes. The findings showed inconsistent evidence for improving outcomes, and future studies should include implementation outcomes, consumer and clinician perspectives, and fracture or bone mineral density outcomes with sufficient follow-up duration.
Article
Public, Environmental & Occupational Health
Kate Johnston-Ataata, Jacinthe Fiore, Renata Kokanovic, Martha Hickey, Helena Teede, Jacqueline A. Boyle, Amanda Vincent
SOCIOLOGY OF HEALTH & ILLNESS
(2020)
