Review
Obstetrics & Gynecology
S. Salvatore, A. F. Ruffolo, C. Phillips, S. Athanasiou, L. Cardozo, M. Serati, EUGA Working Grp
Summary: Vulvovaginal atrophy (VVA) is a chronic progressive condition related to decreased estrogen levels during menopause. Genitourinary syndrome of menopause (GSM) is a more accurate and accepted term for VVA. First-line therapy includes lubricants or moisturizers, with low-dose vaginal estrogens as an option. Laser therapy has been shown to be effective and safe for treating GSM symptoms in postmenopausal women and breast cancer survivors.
Review
Medicine, General & Internal
David Lukanovic, Marija Batkoska, Gorazd Kavsek, Mirjam Druskovic
Summary: Intraamniotic infection, also known as chorioamnionitis, is an inflammatory infection that can affect the amniotic fluid, placenta, fetus, fetal membranes, umbilical cord, or decidua. The treatment of chorioamnionitis varies widely due to different bacterial causes and limited evidence-based guidelines. Antibiotic therapy alone is not sufficient to cure chorioamnionitis, and delivery may be necessary for complete recovery.
FRONTIERS IN MEDICINE
(2023)
Article
Chemistry, Multidisciplinary
Wei Jeng, Yen-Ming Huang, Hsun-Yu Chan, Chi-Chuan Wang
Summary: This article discusses how health behaviors related to COVID-19 prevention measures, especially vaccination, can become channels for misinformation and disinformation, leading to an infodemic, where false information spreads more rapidly and widely than truthful, science-based information. It highlights the harmful implications of such events and explores issues related to scientific communication, public perception of information, and factors influencing individual decision-making.
JOURNAL OF CONTROLLED RELEASE
(2022)
Review
Gastroenterology & Hepatology
Alina Buliarca, Adelina Horhat, Tudor Mocan, Rares Craciun, Bogdan Procopet, Zeno Sparchez
Summary: Liver disease can affect the balance of the hemostatic system, leading to bleeding issues, but rotational thromboelastometry (ROTEM) and thromboelastography (TEG) provide a more comprehensive evaluation of hemostasis. These tests offer more accurate prediction of bleeding risk and can help reduce the use of blood products transfusion.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Review
Oncology
Aikaterini Aravantinou-Fatorou, Angeliki Andrikopoulou, Michael Liontos, Oraianthi Fiste, Vasiliki E. Georgakopoulou, Meletios-Athanasios Dimopoulos, Maria Gavriatopoulou, Flora Zagouri
Summary: This study systematically reviewed the efficacy and safety of pembrolizumab in endometrial cancer and found it to be an effective and safe therapeutic option. Ongoing trials are expected to further confirm its efficacy in this patient population.
Article
Oncology
Jacqueline M. Soegaard Ballester, Kristin E. Goodsell, Jae P. Ermer, Giorgos C. Karakousis, John T. Miura, Nicole M. Saur, Najjia N. Mahmoud, Ari Brooks, Julia C. Tchou, Peter E. Gabriel, Lawrence N. Shulman, Heather Wachtel
Summary: The evaluation of current documentation practices at the institution revealed heterogeneity in baseline concordance rates across surgeons and procedures, indicating the need for improvement and innovation with the introduction of an electronic synoptic documentation tool.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Review
Medicine, General & Internal
Emi Dika, Martina Lambertini, Cristina Pellegrini, Giulia Veronesi, Barbara Melotti, Mattia Riefolo, Francesca Sperandi, Annalisa Patrizi, Costantino Ricci, Martina Mussi, Maria Concetta Fargnoli
Summary: Melanomas arising at uncommon sites are related to specific ethnic groups, limiting patient participation in trials but having important therapeutic implications. Prompt diagnosis and differentiation in treatment approach are crucial for changing the prognosis.
JOURNAL OF CLINICAL MEDICINE
(2021)
Editorial Material
Biochemistry & Molecular Biology
Flaminia Kaluthantrige Don, Meritxell Huch
Summary: Organoid cultures are promising for both basic and clinical research, with potential breakthroughs, but are currently facing bottlenecks that hinder their full exploitation.
TRENDS IN MOLECULAR MEDICINE
(2021)
Review
Orthopedics
Patrick Albright, Evan Banks, Lily Wood, Caitlin Chambers, Ann Van Heest
Summary: There is a lack of diversity in terms of sex, race, and ethnicity in the leadership of orthopaedic societies in the United States. More detailed recording of these data by societies can help track improvements in diversity among members and leaders. Academic participation may be one factor in leadership selection, but other important factors are also involved. Overall transparency in leadership selection criteria could be improved among orthopaedic societies.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2022)
Article
Medicine, General & Internal
Jedrzej Dragan, Jagoda Kania, Maciej Salagierski
Summary: Prostate cancer is the most common cancer in men, with increasing incidence related to factors such as longer life expectancy, PSA testing, and MRI imaging. Active surveillance has been shown to be an effective strategy for low-risk patients, with low rates of metastasis and prostate cancer specific mortality.
ARCHIVES OF MEDICAL SCIENCE
(2021)
Review
Chemistry, Multidisciplinary
Angelo Naselli, Andrea Guarneri, Giacomo Maria Pirola
Summary: Confocal laser endomicroscopy (CLE) shows promise as a valuable tool for bladder cancer management. Despite technical limitations, preliminary studies have demonstrated a high correspondence rate between CLE and histopathological examination. However, further investigations are needed to address potential biases in quality assessment.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Medicinal
Rachel J. J. Stephenson, Istvan Toth
Summary: Cocaine is a widely used illegal drug that has significant medical and social consequences. The lack of effective pharmacological treatments has led to the development of anti-cocaine vaccines. Despite years of research, no approved pharmacological treatments exist to help individuals overcome cocaine addiction or prevent relapse.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Editorial Material
Pharmacology & Pharmacy
Hedva Barenholtz Levy
Summary: Aducanumab's approval for treating Alzheimer's disease by the FDA has been controversial due to concerns about the premature decision and the lack of conclusive clinical effectiveness evidence. Although the drug received accelerated approval, its role in AD treatment remains uncertain pending further postapproval trials to confirm clinical effectiveness.
ANNALS OF PHARMACOTHERAPY
(2022)
Article
Obstetrics & Gynecology
Snigdha Alur-Gupta, Michelle Vu, Wendy Vitek
Summary: Adolescence is a period of flux where fertility preservation options need to be considered, especially in cases of diseases like cancer. Options for fertility preservation vary depending on pubertal status. It is important to consider individual characteristics and disease specifics when making decisions about fertility preservation.
SEMINARS IN REPRODUCTIVE MEDICINE
(2022)
Article
Nursing
Barbara Riegel, Sandra B. Dunbar, Donna Fitzsimons, Kenneth E. Freedland, Christopher S. Lee, Sandy Middleton, Anna Stromberg, Ercole Vellone, David E. Webber, Tiny Jaarsma
Summary: This article discusses the importance and objectives of self-care research, proposes a future research agenda, and shares the vision and mission of a research center dedicated to self-care. It emphasizes the importance of addressing challenges in self-care and strategies to tackle knowledge gaps.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2021)
