Article
Medical Laboratory Technology
Fabio Angeli, Paolo Verdecchia, Stefano Savonitto, Sara Cavallini, Andrea Santucci, Stefano Coiro, Rocco Sclafani, Clara Riccini, Stefano De Servi, Claudio Cavallini
Summary: This study found that higher levels of sCD40L predict an increased risk of acute coronary events and coronary restenosis among patients with ACS or CCS undergoing PCI, but not of mortality.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Valentino Bianco, Suresh Mulukutla, Edgar Aranda-Michel, Danny Chu, David Kaczorowski, Johannes Bonatti, Pyongsoo Yoon, Dustin Kliner, Catalin Toma, Yisi Wang, Steve Koscumb, Floyd Thoma, Forozan Navid, Derek Serna-Gallegos, Ibrahim Sultan
Summary: This study compares the outcomes of multiarterial grafting and percutaneous coronary intervention (PCI) in patients with multivessel coronary disease. It found that multiarterial grafting is associated with fewer adverse events, improved survival, and reduced hospital readmissions for appropriate patients.
ANNALS OF THORACIC SURGERY
(2023)
Article
Urology & Nephrology
Naofumi Ikeda, Toshihide Hayashi, Shikou Gen, Nobuhiko Joki, Kazuhiko Aramaki
Summary: The study aimed to determine the location of coronary atherosclerosis distribution in patients with chronic kidney disease (CKD). The results showed that the prevalence of lesions in the right coronary artery (RCA) increased with worsening CKD stage, while there was no significant change in the lesions of the left anterior descending coronary artery (LAD) and left circumflex coronary artery (LCX). This suggests that the pathophysiology of coronary atherosclerosis may differ by lesion location, and deterioration of renal function may play a more important role in the progression of atherosclerosis in the RCA.
Article
Multidisciplinary Sciences
Jangho Park, Sangwoo Park, Yong-Giun Kim, Soe Hee Ann, Hyun Woo Park, Jon Suh, Jae-Hyung Roh, Young-Rak Cho, Seungbong Han, Gyung-Min Park
Summary: An analysis of National Health Insurance data in Korea showed that pre-existing depression does not have a significant impact on mortality in patients with established coronary artery disease undergoing PCI. However, younger patients with angina and depression may have a higher risk of all-cause mortality.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
J. Hunter Mehaffey, J. W. Awori Hayanga, Mohammad Kawsara, Ankit Sakhuja, Christopher Mascio, J. Scott Rankin, Vinay Badhwar
Summary: Contemporary real-world data from Medicare patients with multivessel disease reveal that coronary artery bypass grafting (CABG) outcomes were superior to percutaneous coronary intervention (PCI), providing important longitudinal data to guide patient care and policy development.
ANNALS OF THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Jun Gu, Zhao-fang Yin, Zuo-jun Xu, Yu-qi Fan, Chang-qian Wang, Jun-feng Zhang
Summary: This study showed that after PCI, the predominant subtype of HF is HFpEF, and higher BNP levels, lower eGFR levels, and atrial fibrillation are independent risk factors for new-onset HF. Being male and being prescribed with ACEI/ARB medications are negative predictors for new-onset HF. Additionally, long-term ACEI/ARB therapy is associated with reduced risks of developing all three subtypes of HF (HFrEF, HFmrEF, and HFpEF), compared to beta-blocker use.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Tineke H. Pinxterhuis, Eline H. Ploumen, Paolo Zocca, Carine J. M. Doggen, Carl E. Schotborgh, Rutger L. Anthonio, Ariel Roguin, Peter W. Danse, Edouard Benit, Adel Aminian, Marc Hartmann, Gerard C. M. Linssen, Clemens von Birgelen
Summary: This study assessed the risk profile and 3-year outcome differences between patients undergoing percutaneous coronary intervention (PCI) for premature and non-premature coronary artery disease (CAD). The results showed that patients with premature CAD had fewer risk factors, but higher rates of smoking and overweight. Additionally, premature CAD patients had lower all-cause mortality risk but higher risks of target vessel revascularization and stent thrombosis.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Michele Gallo, David Blitzer, Pietro L. Laforgia, Ilias P. Doulamis, Nils Perrin, Giacomo Bortolussi, Alvise Guariento, Alessandro Putzu
Summary: The study compared the outcomes of percutaneous coronary intervention (PCI) with drug-eluting stents and coronary artery bypass graft (CABG) for left main coronary artery disease. Results showed that PCI and CABG did not have significant differences in early or 5-year mortality, but exhibited varying rates of stroke, myocardial infarction, and repeat revascularization.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Multidisciplinary Sciences
Takao Konishi, Saikat Kumar B. Ghosh, Yu Sato, Rika Kawakami, Kenji Kawai, Aimee E. Vozenilek, Weili Xu, Arielle Bellissard, Robert Giasolli, Diljon Chahal, Renu Virmani, Aloke V. V. Finn
Summary: This study investigated the thickness of the coronary medial and found that it varies depending on the coronary artery itself, its segments, and branches. The findings are important for coronary intervention and product development.
Article
Cardiac & Cardiovascular Systems
Doosup Shin, Neng Dai, Seung Hun Lee, Ki Hong Choi, Adrien Lefieux, David Molony, Doyeon Hwang, Hyun Kuk Kim, Ki-Hyun Jeon, Hyun-Jong Lee, Ho-Jun Jang, Sang Lin Ha, Taek Kyu Park, Jeong Hoon Yang, Young Bin Song, Joo-Yong Hahn, Seung-Hyuk Choi, Joon-Hyung Doh, Eun-Seok Shin, Chang-Wook Nam, Bon-Kwon Koo, Hyeon-Cheol Gwon, Junbo Ge, Joo Myung Lee
Summary: This study aimed to evaluate the prognostic implications of physiological 2-dimensional disease patterns in relation to the distribution and local severity of coronary atherosclerosis. The study found that disease patterns significantly influenced post-PCI physiological results and determined the risk of target vessel failure.
JACC-CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Medicine, General & Internal
Wojciech Jan Skorupski, Marta Kaluzna-Oleksy, Przemyslaw Mitkowski, Wlodzimierz Skorupski, Stefan Grajek, Malgorzata Pyda, Aleksander Araszkiewicz, Maciej Lesiak, Marek Grygier
Summary: Periprocedural myocardial injury is common after left main percutaneous coronary interventions, but its prognostic significance remains unclear. This study suggests that isolated periprocedural troponin elevation is not clinically significant for long-term outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Nicholas W. S. Chew, Jin Hean Koh, Cheng Han Ng, Darren Jun Hao Tan, Jie Ning Yong, Chaoxing Lin, Oliver Zi-Hern Lim, Yip Han Chin, Denzel Ming Wei Lim, Koo Hui Chan, Poay-Huan Loh, Adrian Low, Chi-Hang Lee, Huay-Cheem Tan, Mark Chan
Summary: This study conducted a two-stage meta-analysis using reconstructed individual patient data to compare long-term mortality between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for patients with multivessel disease (MVD) without left main (LM) involvement. The results showed that CABG had a lower cumulative all-cause mortality compared to PCI for MVD patients without LM involvement. However, in patients with moderate to high SYNTAX score, PCI had a significantly higher 10-year all-cause mortality compared to CABG.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Multidisciplinary Sciences
Shinsuke Muraoka, Daiki Somiya, Aoi Ebata, Yuki Kumagai, Naoki Koketsu
Summary: This study investigated the prevalence of cerebrovascular events (CVEs) after PCI in the chronic phase, finding significant associations with the number of Coronary Artery Calcification (CAC) sites and post-PCI for chronic coronary syndrome. The study proposed a new and easy CAC evaluation method that accurately reflected future CVEs risk and may have clinical applicability.
Review
Cell Biology
Bradley Tucker, Kaivan Vaidya, Blake J. Cochran, Sanjay Patel
Summary: Periprocedural myocardial injury and myocardial infarction are common complications of percutaneous coronary intervention, associated with increased short- and long-term mortality. Inflammation levels before, during, and after the procedure are linked to higher rates of myonecrosis and future cardiovascular events. In addition to inflammation from underlying coronary disease, PCI itself triggers an acute inflammatory response.
Article
Cardiac & Cardiovascular Systems
Ziwei Xi, Jianan Li, Hong Qiu, Tingting Guo, Yong Wang, Yang Li, Jianfeng Zheng, Kefei Dou, Bo Xu, Yongjian Wu, Shubin Qiao, Weixian Yang, Yuejin Yang, Runlin Gao
Summary: This study demonstrates that in patients with SCAD undergoing complex PCI, ticagrelor can significantly reduce the risk of adverse cardiovascular events compared to clopidogrel, without an increased risk of major bleeding.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
