Mechanistic Studies of Viral Entry: An Overview of Dendrimer-Based Microbicides As Entry Inhibitors Against Both HIV and HSV-2 Overlapped Infections

Recent advances on anti-HIV vaginal delivery systems development

(2015) Sophia G. Antimisiaris et al.   ADVANCED DRUG DELIVERY REVIEWS

Sphingolipids in viral infection

(2015) Jürgen Schneider-Schaulies et al.   BIOLOGICAL CHEMISTRY

Tryptophan dendrimers that inhibit HIV replication, prevent virus entry and bind to the HIV envelope glycoproteins gp120 and gp41

(2015) Eva Rivero-Buceta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

HIV-1 antiviral behavior of anionic PPI metallo-dendrimers with EDA core

(2015) Sandra García-Gallego et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Anti-Human Immunodeficiency Virus Activity of Thiol-Ene Carbosilane Dendrimers and Their Potential Development as a Topical Microbicide

(2015) Javier Sánchez-Rodríguez et al.   Journal of Biomedical Nanotechnology

Nanostructures for the Inhibition of Viral Infections

(2015) Sabine Szunerits et al.   MOLECULES

Prevention vaginally of HIV-1 transmission in humanized BLT mice and mode of antiviral action of polyanionic carbosilane dendrimer G2-S16

(2015) Daniel Sepúlveda-Crespo et al.   Nanomedicine-Nanotechnology Biology and Medicine

Polyanionic carbosilane dendrimer-conjugated antiviral drugs as efficient microbicides: Recent trends and developments in HIV treatment/therapy

(2015) Daniel Sepúlveda-Crespo et al.   Nanomedicine-Nanotechnology Biology and Medicine

Development of water-soluble polyanionic carbosilane dendrimers as novel and highly potent topical anti-HIV-2 microbicides

(2015) Verónica Briz et al.   Nanoscale

The SPL7013 dendrimer destabilizes the HIV-1 gp120–CD4 complex

(2015) Bidisha Nandy et al.   Nanoscale

HIV Vaccine Research: The Challenge and the Way Forward

(2015) Hai-Bo Wang et al.   Journal of Immunology Research

A multivalent inhibitor of the DC-SIGN dependent uptake of HIV-1 and Dengue virus

(2014) Norbert Varga et al.   BIOMATERIALS

Synthesis of anionic carbosilane dendrimers via “click chemistry” and their antiviral properties against HIV

(2014) Eduardo Arnáiz et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

HIV infection: epidemiology, pathogenesis, treatment, and prevention

(2014) Gary Maartens et al.   LANCET

Synthesis of new anionic carbosilane dendrimers via thiol–ene chemistry and their antiviral behaviour

(2014) Marta Galán et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Dendrimers: synthesis, applications, and properties

(2014) Elham Abbasi et al.   Nanoscale Research Letters

Development of sulphated and naphthylsulphonated carbosilane dendrimers as topical microbicides to prevent HIV-1 sexual transmission

(2013) Enrique Vacas Córdoba et al.   AIDS

Restrictions to HIV-1 replication in resting CD4+ T lymphocytes

(2013) Xiaoyu Pan et al.   CELL RESEARCH

Glycodendrimers prevent HIV transmission via DC-SIGN on dendritic cells

(2013) J. J. Garcia-Vallejo et al.   INTERNATIONAL IMMUNOLOGY

Simulations reveal that the HIV-1 gp120-CD4 complex dissociates via complex pathways and is a potential target of the polyamidoamine (PAMAM) dendrimer

(2013) Bidisha Nandy et al.   JOURNAL OF CHEMICAL PHYSICS

Peptide-Derivatized SB105-A10 Dendrimer Inhibits the Infectivity of R5 and X4 HIV-1 Strains in Primary PBMCs and Cervicovaginal Histocultures

(2013) Isabella Bon et al.   PLoS One

Microbicides: Topical Prevention against HIV

(2013) R. J. Shattock et al.   Cold Spring Harbor Perspectives in Medicine

HIV entry: a game of hide-and-fuse?

(2013) Gregory B Melikyan   Current Opinion in Virology

Human Immunodeficiency Virus and Heparan Sulfate: From Attachment to Entry Inhibition

(2013) Bridgette J. Connell et al.   Frontiers in Immunology

Multivalency as a Chemical Organization and Action Principle

(2012) Carlo Fasting et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of a new amphiphilic glycodendrimer with antiviral functionality

(2012) Shuqin Han et al.   CARBOHYDRATE POLYMERS

The molecular basis of HIV entry

(2012) Per Johan Klasse   CELLULAR MICROBIOLOGY

DC-SIGN Antagonists, a Potential New Class of Anti-Infectives

(2012) M. Anderluh et al.   CURRENT MEDICINAL CHEMISTRY

Antiviral Properties Against HIV of Water Soluble Copper Carbosilane Dendrimers and their EPR Characterization

(2012) M. Galan et al.   CURRENT MEDICINAL CHEMISTRY

Synthesis, structure and molecular modelling of anionic carbosilane dendrimers

(2012) Beatriz Rasines et al.   DALTON TRANSACTIONS

Role of heparan sulfate in sexually transmitted infections

(2012) V. Tiwari et al.   GLYCOBIOLOGY

Trans-infection but Not Infection from within Endosomal Compartments after Cell-to-cell HIV-1 Transfer to CD4+T Cells

(2012) Marc Permanyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV Entry and Envelope Glycoprotein-mediated Fusion

(2012) Robert Blumenthal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carbosilane dendrimer nanotechnology outlines of the broad HIV blocker profile

(2012) L. Chonco et al.   JOURNAL OF CONTROLLED RELEASE

HIV-1 X4 Activities of Polycationic “Viologen” Based Dendrimers by Interaction with the Chemokine Receptor CXCR4: Study of Structure–Activity Relationship

(2012) Simona Asaftei et al.   JOURNAL OF MEDICINAL CHEMISTRY

Efficacy Results of a Trial of a Herpes Simplex Vaccine

(2012) Robert B. Belshe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intercellular Adhesion Molecule 1 Promotes HIV-1 Attachment but Not Fusion to Target Cells

(2012) Naoyuki Kondo et al.   PLoS One

Herpes Virus Fusion and Entry: A Story with Many Characters

(2012) Roselyn J. Eisenberg et al.   Viruses-Basel

Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties

(2012) Aliana López de Victoria et al.   BMC Biophysics

Inhibition of Herpes Simplex Virus Type 1 and Type 2 Infections by Peptide-Derivatized Dendrimers

(2011) Anna Luganini et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The rise and fall of polyanionic inhibitors of the human immunodeficiency virus type 1

(2011) Vanessa Pirrone et al.   ANTIVIRAL RESEARCH

Evaluation of the Synthesis of Sialic Acid-PAMAM Glycodendrimers without the Use of Sugar Protecting Groups, and the Anti-HIV-1 Properties of These Compounds

(2011) Russell Clayton et al.   BIOCONJUGATE CHEMISTRY

Herpes simplex virus infects most cell types in vitro: clues to its success

(2011) Ghadah A Karasneh et al.   Virology Journal

Glycosphingolipid Functions

(2011) C. A. Lingwood   Cold Spring Harbor Perspectives in Biology

Heparan Sulfate Proteoglycans

(2011) S. Sarrazin et al.   Cold Spring Harbor Perspectives in Biology

Inhibition of DC-SIGN-Mediated HIV Infection by a Linear Trimannoside Mimic in a Tetravalent Presentation

(2010) Sara Sattin et al.   ACS Chemical Biology

Identification of a Dendrimeric Heparan Sulfate-Binding Peptide That Inhibits Infectivity of Genital Types of Human Papillomaviruses

(2010) M. Donalisio et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dendrimers as Potential Inhibitors of the Dimerization of the Capsid Protein of HIV-1

(2010) Rosa Doménech et al.   BIOMACROMOLECULES

Sulfated oligosaccharide cluster with polylysine core scaffold as a new anti-HIV dendrimer

(2010) Shuqin Han et al.   CARBOHYDRATE POLYMERS

The multiple facets of HIV attachment to dendritic cell lectins

(2010) Theodros Solomon Tsegaye et al.   CELLULAR MICROBIOLOGY

C-type lectin DC-SIGN: An adhesion, signalling and antigen-uptake molecule that guides dendritic cells in immunity

(2010) Urban Švajger et al.   CELLULAR SIGNALLING

Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine

(2010) Didier Astruc et al.   CHEMICAL REVIEWS

Synthesis of Hyperbranched β-Galceramide-Containing Dendritic Polymers that Bind HIV-1 rgp120

(2010) José Antonio Morales-Serna et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

“Viologen” Dendrimers as Antiviral Agents: The Effect of Charge Number and Distance†

(2010) Simona Asaftei et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cascade of Events Governing Cell-Cell Fusion Induced by Herpes Simplex Virus Glycoproteins gD, gH/gL, and gB

(2010) D. Atanasiu et al.   JOURNAL OF VIROLOGY

Structure Activity Relationship of Dendrimer Microbicides with Dual Action Antiviral Activity

(2010) David Tyssen et al.   PLoS One

Aliphatic hyperbranched polyesters based on 2,2-bis(methylol)propionic acid—Determination of structure, solution and bulk properties

(2010) Ema Žagar et al.   PROGRESS IN POLYMER SCIENCE

Synthesis of carbosilane dendrons and dendrimers derived from 1,3,5-trihydroxybenzene

(2010) Javier Sánchez-Nieves et al.   TETRAHEDRON

Multivalent dendrimeric compounds containing carbohydrates expressed on immune cells inhibit infection by primary isolates of HIV-1

(2010) Andrew Rosa Borges et al.   VIROLOGY

An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes

(2010) Jasminka Sterjovski et al.   VIROLOGY

Characterization of Human Immunodeficiency Virus Type 1 Populations Containing CXCR4-Using Variants from Recently Infected Individuals

(2009) Wei Huang et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Multivalent catanionic GalCer analogs derived from first generation dendrimeric phosphonic acids

(2009) Alexandra Pérez-Anes et al.   BIOORGANIC & MEDICINAL CHEMISTRY

HIV Enters Cells via Endocytosis and Dynamin-Dependent Fusion with Endosomes

(2009) Kosuke Miyauchi et al.   CELL

The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly

(2009) José L. Neira   FEBS Journal

Lectins as pattern recognition molecules: The effects of epitope density in innate immunity

(2009) T. K Dam et al.   GLYCOBIOLOGY

Differences in molecular evolution between switch (R5 to R5X4/X4-tropic) and non-switch (R5-tropic only) HIV-1 populations during infection

(2009) Mattias Mild et al.   INFECTION GENETICS AND EVOLUTION

Herpes Simplex Virus gD Forms Distinct Complexes with Fusion Executors gB and gH/gL in Part through the C-terminal Profusion Domain

(2009) Tatiana Gianni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphonate terminated PPH dendrimers: influence of pendant alkyl chains on the in vitro anti-HIV-1 properties

(2009) Alexandra Pérez-Anes et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The integrin  4 7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1

(2009) C. Cicala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herpes simplex virus type 2 and syphilis infections with HIV: an evolving synergy in transmission and prevention

(2009) Aaron AR Tobian et al.   Current Opinion in HIV and AIDS

Entry of herpesviruses into mammalian cells

(2008) E. E. Heldwein et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Maraviroc: A CCR5-receptor antagonist for the treatment of HIV-1 infection

(2008) Sharon S. Lieberman-Blum et al.   CLINICAL THERAPEUTICS

Distribution and lateral mobility of DC-SIGN on immature dendritic cells-implications for pathogen uptake

(2008) A. K. Neumann et al.   JOURNAL OF CELL SCIENCE

Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN

(2008) S.-K. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The genital tract immune milieu: an important determinant of HIV susceptibility and secondary transmission

(2007) R. Kaul et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY