期刊
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
卷 -, 期 -, 页码 -出版社
HIGHER EDUCATION PRESS
DOI: 10.1007/s40242-023-3204-0
关键词
Poor water solubility; Inclusion complex; Physicochemical; Biopharmaceutical
Host-guest inclusion complexes, particularly cyclodextrin-based complexes, have been widely studied for drug delivery applications. These complexes can protect drugs, improve their solubility and stability, and enable targeted drug delivery.
Host-guest inclusion complexes have been extensively studied for drug delivery applications. The host molecule, typically cyclodextrin, creates a cavity, in which the guest molecule, such as a drug, can be encapsulated. This encapsulation can protect the drug from degradation, improve its solubility and stability, and enhance its bioavailability. Moreover, host-guest inclusion complexes can facilitate targeted drug delivery by selectively releasing drugs at the site of action. Various techniques, such as covalent bonding, non-covalent interactions, and self-assembly have been used to form these complexes. Host-guest inclusion complexes have shown great potential for improving the efficacy and safety of drug delivery systems. This mini review summarizes the application and recent progress of the cyclodextrin-based host-guest inclusion complex, highlighting the enhanced physicochemical and biopharmaceutical application of pharmaceutical drugs via formulation of its inclusion complex.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据