Deciphering the decline of metabolic elasticity in aging and obesity

Adipose-tissue plasticity in health and disease

(2022) Alexander Sakers et al.   CELL

A single-cell atlas of human and mouse white adipose tissue

(2022) Margo P. Emont et al.   NATURE

Cell transcriptomic atlas of the non-human primate Macaca fascicularis

(2022) Lei Han et al.   NATURE

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

PPAR control of metabolism and cardiovascular functions

(2021) David Montaigne et al.   Nature Reviews Cardiology

A Landscape of Murine Long Non-Coding RNAs Reveals the Leading Transcriptome Alterations in Adipose Tissue during Aging

(2020) Qiuzhong Zhou et al.   Cell Reports

Metabolic Communication and Healthy Aging: Where Should We Focus Our Energy?

(2020) Hannah J. Smith et al.   DEVELOPMENTAL CELL

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

(2020)   NATURE

Ageing hallmarks exhibit organ-specific temporal signatures

(2020) Nicholas Schaum et al.   NATURE

Plasticity of Epididymal Adipose Tissue in Response to Diet-Induced Obesity at Single-Nucleus Resolution

(2020) Anitta Kinga Sárvári et al.   Cell Metabolism

ChEA3: transcription factor enrichment analysis by orthogonal omics integration

(2019) Alexandra B Keenan et al.   NUCLEIC ACIDS RESEARCH

Effects of Intermittent Fasting on Health, Aging, and Disease

(2019) Rafael de Cabo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metabolic flexibility as an adaptation to energy resources and requirements in health and disease

(2018) Reuben L Smith et al.   ENDOCRINE REVIEWS

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

GENCODE reference annotation for the human and mouse genomes

(2018) Adam Frankish et al.   NUCLEIC ACIDS RESEARCH

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Distinct but complementary contributions of PPAR isotypes to energy homeostasis

(2017) Vanessa Dubois et al.   JOURNAL OF CLINICAL INVESTIGATION

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease

(2016) José J. Fuster et al.   CIRCULATION RESEARCH

Tipping the metabolic scales towards increased longevity in mammals

(2015) Celine E. Riera et al.   NATURE CELL BIOLOGY

The metabolic regulation of aging

(2015) Toren Finkel   NATURE MEDICINE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

The role of low-grade inflammation and metabolic flexibility in aging and nutritional modulation thereof: A systems biology approach

(2014) Dulce Calçada et al.   MECHANISMS OF AGEING AND DEVELOPMENT

PPARγ and the global map of adipogenesis and beyond

(2014) Martina I. Lefterova et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

The Critical Role of Metabolic Pathways in Aging

(2012) N. Barzilai et al.   DIABETES

Thiazolidinediones on PPARγ: The Roles in Bone Remodeling

(2011) Wei Wei et al.   PPAR Research

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

(2010) Daniele Merico et al.   PLoS One