Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage
出版年份 2023 全文链接
标题
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage
作者
关键词
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出版物
Cell Metabolism
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2023-10-27
DOI
10.1016/j.cmet.2023.10.001
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- BMP7-based peptide agonists of BMPR1A protect the left ventricle against pathological remodeling induced by pressure overload
- (2022) Ana B. Salido-Medina et al. BIOMEDICINE & PHARMACOTHERAPY
- BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states
- (2022) Joep Beumer et al. Cell Reports
- A Process for the Design and Development of Novel Bone Morphogenetic Protein-7 (BMP-7) Mimetics With an Example: THR-184
- (2022) William D. Carlson et al. Frontiers in Pharmacology
- Single-nucleus RNA-sequencing reveals singular gene signatures of human ductal cells during adaptation to insulin resistance
- (2022) Ercument Dirice et al. JCI Insight
- Single-cell transcriptomic and spatial landscapes of the developing human pancreas
- (2022) Oladapo Edward Olaniru et al. Cell Metabolism
- Temporal single-cell regeneration studies: the greatest thing since sliced pancreas?
- (2021) Juan Domínguez-Bendala et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Islet β Cells Physiological Difference Study of Old and Young Mice Based on Single Cell Transcriptomics.
- (2021) Zheng Zeyu et al. Journal of Diabetes Investigation
- Single-Cell Analyses of Human Pancreas: Characteristics of two populations of acinar cells in chronic pancreatitis
- (2021) Brandon M Blobner et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip
- (2021) Sandra Wiedenmann et al. Nature Biomedical Engineering
- Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes
- (2020) Joan Camunas-Soler et al. Cell Metabolism
- Secretory Functions of Macrophages in the Human Pancreatic Islet Are Regulated by Endogenous Purinergic Signaling
- (2020) Jonathan R. Weitz et al. DIABETES
- Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche
- (2020) Mirza Muhammad Fahd Qadir et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Generalizing RNA velocity to transient cell states through dynamical modeling
- (2020) Volker Bergen et al. NATURE BIOTECHNOLOGY
- Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis
- (2020) Julia K. Panzer et al. JCI Insight
- Organisation of the human pancreas in health and in diabetes
- (2020) Mark A. Atkinson et al. DIABETOLOGIA
- Autophagy in the Regulation of Tissue Differentiation and Homeostasis
- (2020) Cristiana Perrotta et al. Frontiers in Cell and Developmental Biology
- Single-Nucleus and In Situ RNA–Sequencing Reveal Cell Topographies in the Human Pancreas
- (2020) Luca Tosti et al. GASTROENTEROLOGY
- Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes
- (2019) Zhou Fang et al. Cell Reports
- NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP)
- (2019) Klaus H. Kaestner et al. DIABETES
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- Downregulation of the Helicase Lymphoid-Specific (HELLS) Gene Impairs Cell Proliferation and Induces Cell Cycle Arrest in Colorectal Cancer Cells
- (2019) Xi Liu et al. OncoTargets and Therapy
- SOX9+/PTF1A+ Cells Define the Tip Progenitor Cells of the Human Fetal Pancreas of the Second Trimester
- (2019) Valentina Villani et al. Stem Cells Translational Medicine
- Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges
- (2018) Julie B. Sneddon et al. Cell Stem Cell
- P2RY1/ALK3-Expressing Cells within the Adult Human Exocrine Pancreas Are BMP-7 Expandable and Exhibit Progenitor-like Characteristics
- (2018) Mirza Muhammad Fahd Qadir et al. Cell Reports
- RNA velocity of single cells
- (2018) Gioele La Manno et al. NATURE
- Single-Cell RNA-Seq of the Pancreatic Islets––a Promise Not yet Fulfilled?
- (2018) Yue J. Wang et al. Cell Metabolism
- Pancreatic Progenitors: There and Back Again
- (2018) Juan Domínguez-Bendala et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Perioperative THR-184 and AKI after Cardiac Surgery
- (2017) Jonathan Himmelfarb et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Reversed graph embedding resolves complex single-cell trajectories
- (2017) Xiaojie Qiu et al. NATURE METHODS
- Acute kidney injury: emerging pharmacotherapies in current clinical trials
- (2017) Stefanie Woolridge Benoit et al. PEDIATRIC NEPHROLOGY
- Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
- (2017) Kathryn F. Cogger et al. Nature Communications
- Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2 + Human Pancreatic Progenitors
- (2017) Jacqueline Ameri et al. Cell Reports
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
- (2016) Åsa Segerstolpe et al. Cell Metabolism
- De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data
- (2016) Dominic Grün et al. Cell Stem Cell
- Single-Cell Analysis Uncovers Clonal Acinar Cell Heterogeneity in the Adult Pancreas
- (2016) Damian Wollny et al. DEVELOPMENTAL CELL
- Single-Cell Transcriptomics of the Human Endocrine Pancreas
- (2016) Yue J. Wang et al. DIABETES
- Stress-induced adaptive islet cell identity changes
- (2016) V. Cigliola et al. DIABETES OBESITY & METABOLISM
- Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes
- (2016) Nathan Lawlor et al. GENOME RESEARCH
- Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
- (2016) Maxim V. Kuleshov et al. NUCLEIC ACIDS RESEARCH
- Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation
- (2016) Ivan Achel Valdez et al. Cell Reports
- A Single-Cell Transcriptome Atlas of the Human Pancreas
- (2016) Mauro J. Muraro et al. Cell Systems
- A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure
- (2016) Maayan Baron et al. Cell Systems
- Regeneration and Repair of the Exocrine Pancreas
- (2015) L. Charles Murtaugh et al. Annual Review of Physiology
- BMP-7 Induces Adult Human Pancreatic Exocrine-to-Endocrine Conversion
- (2015) Dagmar Klein et al. DIABETES
- Pairing-up SOX to kick-start beta cell genesis
- (2015) Anne Grapin-Botton et al. DIABETOLOGIA
- SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models
- (2015) Eric E. Xu et al. DIABETOLOGIA
- BMP4 and BMP7 Suppress StAR and Progesterone Production via ALK3 and SMAD1/5/8-SMAD4 in Human Granulosa-Lutein Cells
- (2015) Han Zhang et al. ENDOCRINOLOGY
- Activation of pancreatic stellate cells involves an EMT-like process
- (2015) LEI TIAN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Pancreatic duct glands (PDGs) are a progenitor compartment responsible for pancreatic ductal epithelial repair
- (2015) Junpei Yamaguchi et al. Stem Cell Research
- The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
- (2014) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- Dynamic reciprocity: the role of annexin A2 in tissue integrity
- (2014) Jessica K. Hitchcock et al. Journal of Cell Communication and Signaling
- Id proteins are critical downstream effectors of BMP signaling in human pulmonary arterial smooth muscle cells
- (2013) Jun Yang et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
- (2013) Edward Y Chen et al. BMC BIOINFORMATICS
- Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration
- (2013) F. C. Pan et al. DEVELOPMENT
- Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation
- (2013) Nighat Yasmin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Ultrasensitive fluorescent proteins for imaging neuronal activity
- (2013) Tsai-Wen Chen et al. NATURE
- Recovery from diabetes in neonatal mice after a low-dose streptozotocin treatment
- (2012) Masateru Kataoka et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis
- (2012) Hikaru Sugimoto et al. NATURE MEDICINE
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Suppression of Ptf1a Activity Induces Acinar-to-Endocrine Conversion
- (2011) Daniel Hesselson et al. CURRENT BIOLOGY
- Transcriptomes of the major human pancreatic cell types
- (2011) C. Dorrell et al. DIABETOLOGIA
- Physiology and pathophysiology of matrix metalloproteases
- (2010) T. Klein et al. AMINO ACIDS
- Proliferating cell nuclear antigen (PCNA): a key factor in DNA replication and cell cycle regulation
- (2010) Wojciech Strzalka et al. ANNALS OF BOTANY
- Cellular plasticity of the pancreas
- (2009) Luc Baeyens et al. BIOLOGICAL CHEMISTRY
- OLFM4 Is a Robust Marker for Stem Cells in Human Intestine and Marks a Subset of Colorectal Cancer Cells
- (2009) Laurens G. van der Flier et al. GASTROENTEROLOGY
- Can β-cells be derived from exocrine pancreas?
- (2008) L. Baeyens et al. DIABETES OBESITY & METABOLISM
- In vivo reprogramming of adult pancreatic exocrine cells to β-cells
- (2008) Qiao Zhou et al. NATURE
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