Interpretation of SNP combination effects on schizophrenia etiology based on stepwise deep learning with multi-precision data

Explainable deep transfer learning model for disease risk prediction using high-dimensional genomic data

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Molecular logic of cellular diversification in the mouse cerebral cortex

(2021) Daniela J. Di Bella et al.   NATURE

GenNet framework: interpretable deep learning for predicting phenotypes from genetic data

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Varmole: A biologically drop-connect deep neural network model for prioritizing disease risk variants and genes

(2020) Nam D Nguyen et al.   BIOINFORMATICS

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

(2019) Daehwan Kim et al.   NATURE BIOTECHNOLOGY

HiSSI: high-order SNP-SNP interactions detection based on efficient significant pattern and differential evolution

(2019) Xia Cao et al.   BMC Medical Genomics

Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register

(2018) Rikke Hilker et al.   BIOLOGICAL PSYCHIATRY

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

(2018) Antonio F. Pardiñas et al.   NATURE GENETICS

Using deep learning to model the hierarchical structure and function of a cell

(2018) Jianzhu Ma et al.   NATURE METHODS

The personal and clinical utility of polygenic risk scores

(2018) Ali Torkamani et al.   NATURE REVIEWS GENETICS

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

(2018) Michael J. Gandal et al.   SCIENCE

The Stanley Neuropathology Consortium Integrative Database (SNCID) for Psychiatric Disorders

(2018) Sanghyeon Kim et al.   Neuroscience Bulletin

Integral Characterization of Defective BDNF/TrkB Signalling in Neurological and Psychiatric Disorders Leads the Way to New Therapies

(2017) Gonzalo Tejeda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

A complete tool set for molecular QTL discovery and analysis

(2017) Olivier Delaneau et al.   Nature Communications

RAS and downstream RAF-MEK and PI3K-AKT signaling in neuronal development, function and dysfunction

(2016) Jian Zhong   BIOLOGICAL CHEMISTRY

Schizophrenia

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Reelin Exerts Structural, Biochemical and Transcriptional Regulation Over Presynaptic and Postsynaptic Elements in the Adult Hippocampus

(2016) Carles Bosch et al.   Frontiers in Cellular Neuroscience

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

BDNF promotes the growth of human neurons through crosstalk with the Wnt/β-catenin signaling pathway via GSK-3β

(2015) Jin-wei Yang et al.   NEUROPEPTIDES

Neuronal migration abnormalities and its possible implications for schizophrenia

(2015) Kazue Muraki et al.   Frontiers in Neuroscience

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness

(2014) Jared O'Connell et al.   PLoS Genetics

NCBI’s Database of Genotypes and Phenotypes: dbGaP

(2013) Kimberly A. Tryka et al.   NUCLEIC ACIDS RESEARCH

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

(2012) Oliver Stegle et al.   Nature Protocols

High-Order SNP Combinations Associated with Complex Diseases: Efficient Discovery, Statistical Power and Functional Interactions

(2012) Gang Fang et al.   PLoS One

A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data

(2011) H. Li   BIOINFORMATICS

Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration

(2011) Chikako Harada et al.   Nature Communications

Neuropathological and Reelin Deficiencies in the Hippocampal Formation of Rats Exposed to MAM; Differences and Similarities with Schizophrenia

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Calmodulin-Kinases: Modulators of Neuronal Development and Plasticity

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