Anti-cancer effect of palmatine through inhibition of the PI3K/AKT pathway in canine mammary gland tumor CMT-U27 cells

Palmatine Attenuates Metastatic Lung Colonization of Triple Negative Breast Cancer Cells

(2022) Selase Ativui et al.   Frontiers in Pharmacology

Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis

(2021) Radha Mukherjee et al.   MOLECULAR CELL

Palmatine, a Bioactive Protoberberine Alkaloid Isolated from Berberis cretica, Inhibits the Growth of Human Estrogen Receptor-Positive Breast Cancer Cells and Acts Synergistically and Additively with Doxorubicin

(2021) Aneta Grabarska et al.   MOLECULES

Activating AKT1 and PIK3CA Mutations in Metastatic Castration-Resistant Prostate Cancer

(2020) Cameron Herberts et al.   EUROPEAN UROLOGY

The cell biology behind the oncogenic PIP3 lipids

(2019) Ana C. Carrera et al.   JOURNAL OF CELL SCIENCE

Palmatine: A review of its pharmacology, toxicity and pharmacokinetics

(2019) Jiaying Long et al.   BIOCHIMIE

Somatic Mutation of PIK3CA (H1047R) Is a Common Driver Mutation Hotspot in Canine Mammary Tumors as Well as Human Breast Cancers

(2019) Kang-Hoon Lee et al.   Cancers

Development of an HPLC-DAD method for the determination of five alkaloids in Stephania yunnanensis Lo and in rat plasma after oral dose of Stephania yunnanensis Lo extracts

(2018) Aiyi Xin et al.   BIOMEDICAL CHROMATOGRAPHY

Coptidis rhizoma and its main bioactive components: recent advances in chemical investigation, quality evaluation and pharmacological activity

(2018) Fan-Cheng Meng et al.   Chinese Medicine

Investigational PI3K/AKT/mTOR inhibitors in development for endometrial cancer

(2018) Fabio Barra et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

The anti-sepsis activity of the components of Huanglian Jiedu Decoction with high lipid A-binding affinity

(2017) Guirong Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Elicitor enhanced production of protoberberine alkaloids from in vitro cell suspension cultures of Tinospora cordifolia (Willd.) Miers ex Hook. F. & Thoms

(2017) Peeyush Kumar et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Significance of PI3K/AKT signaling pathway in metastasis of esophageal squamous cell carcinoma and its potential as a target for anti-metastasis therapy

(2017) Bin Li et al.   Oncotarget

Prognostic role of tumorPIK3CAmutation in colorectal cancer: a systematic review and meta-analysis

(2016) Z. B. Mei et al.   ANNALS OF ONCOLOGY

Sinomenine prevents metastasis of human osteosarcoma cells via S phase arrest and suppression of tumor-related neovascularization and osteolysis through the CXCR4-STAT3 pathway

(2016) TAO XIE et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Simultaneous screening and analysis of antiplatelet aggregation active alkaloids from Rhizoma Corydalis

(2016) Qian Zhang et al.   PHARMACEUTICAL BIOLOGY

HS-173, a novel PI3K inhibitor suppresses EMT and metastasis in pancreatic cancer

(2016) Marufa Rumman et al.   Oncotarget

Natural Products for the Treatment of Type 2 Diabetes Mellitus

(2015) José Ríos et al.   PLANTA MEDICA

Investigation of HER2 expression in canine mammary tumors by antibody-based, transcriptomic and mass spectrometry analysis: is the dog a suitable animal model for human breast cancer?

(2015) G. P. Burrai et al.   TUMOR BIOLOGY

Multiscale analysis of the contents of palmatine in the Nature populations of Phellodendron amurense in Northeast China

(2015) Minglong Sun et al.   JOURNAL OF FORESTRY RESEARCH

Palmatine inhibits growth and invasion in prostate cancer cell: Potential role for rpS6/NFκB/FLIP

(2014) Heather G. Hambright et al.   MOLECULAR CARCINOGENESIS

Behavioral and biochemical evidences for antidepressant-like activity of palmatine in mice subjected to chronic unpredictable mild stress

(2014) Dinesh Dhingra et al.   Pharmacological Reports

Regulation of angiogenesis by PI3K signaling networks

(2013) Mariona Graupera et al.   EXPERIMENTAL CELL RESEARCH

Quantum second virial coefficient calculation for the 4He dimer on a recent potential

(2013) Éderson D'Martin Costa et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

Identification and antimicrobial activity of two alkaloids from traditional Chinese medicinal plant Tinospora capillipes

(2012) Yecheng Deng et al.   INDUSTRIAL CROPS AND PRODUCTS

Synthesis and Cytotoxicity Evaluation of 13-n-Alkyl Berberine and Palmatine Analogues as Anticancer Agents

(2012) Lei Zhang et al.   MOLECULES

Antitumor Activity of Noscapine in Combination with Doxorubicin in Triple Negative Breast Cancer

(2011) Mahavir B. Chougule et al.   PLoS One

Variable Inhibition of Thrombospondin 1 against Liver and Lung Metastases through Differential Activation of Metalloproteinase ADAMTS1

(2010) Y.-J. Lee et al.   CANCER RESEARCH

Expression of HER-2 and nuclear localization of HER-3 protein in canine mammary tumors: Histopathological and immunohistochemical study

(2010) J.H. Kim et al.   VETERINARY JOURNAL

Mammary Tumor Recurrence in Bitches After Regional Mastectomy

(2010) NINA STRATMANN et al.   VETERINARY SURGERY

Canine neoplasia - Introductory paper

(2009) HANS GAMLEM et al.   APMIS

A Vascular Targeted Pan Phosphoinositide 3-Kinase Inhibitor Prodrug, SF1126, with Antitumor and Antiangiogenic Activity

(2008) J. R. Garlich et al.   CANCER RESEARCH

Effects of the Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 on the Tumor Vasculature: Implications for Clinical Imaging

(2008) C. R. Schnell et al.   CANCER RESEARCH

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

(2008) S.-M. Maira et al.   MOLECULAR CANCER THERAPEUTICS

Adjuvant gemcitabine after surgical removal of aggressive malignant mammary tumours in dogs

(2008) L. Marconato et al.   Veterinary and Comparative Oncology