RasGRP2 Attenuates Oxygen Deprivation-Induced Autophagy in Vascular Endothelial Cells

RasGRP2 inhibits glyceraldehyde-derived toxic advanced glycation end-products from inducing permeability in vascular endothelial cells

(2021) Jun-ichi Takino et al.   Scientific Reports

Enhanced Autophagy in GAB1-Deficient Vascular Endothelial Cells Is Responsible for Atherosclerosis Progression

(2021) Xin Qian et al.   Frontiers in Physiology

Vascular endothelial cell specification in health and disease

(2021) Corina Marziano et al.   ANGIOGENESIS

Autophagy at the interface of endothelial cell homeostasis and vascular disease

(2021) Eleonora Mameli et al.   FEBS Journal

Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy

(2021) Lu Zhang et al.   Cell Death & Disease

The Role of HIF1α-PFKFB3 Pathway in Diabetic Retinopathy

(2021) Jie Min et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Role of RASGRP2 in Vascular Endothelial Cells—A Mini Review

(2021) Jun-ichi Takino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy-mediated occludin degradation contributes to blood–brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models

(2020) Kyeong-A Kim et al.   Fluids and Barriers of the CNS

Metformin alleviates hyperglycemia-induced endothelial impairment by downregulating autophagy via the Hedgehog pathway

(2019) Chao Niu et al.   Autophagy

RASGRP2 Suppresses Apoptosis via Inhibition of ROS Production in Vascular Endothelial Cells

(2019) Takuma Sato et al.   TheScientificWorldJOURNAL

Primary endothelial–specific regulation of hypoxia-inducible factor (HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia

(2019) Rafal Bartoszewski et al.   FASEB JOURNAL

The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells

(2019) Jun-ichi Takino et al.   Scientific Reports

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

(2018) Mario Mauthe et al.   Autophagy

GLP-1 treatment protects endothelial cells from oxidative stress-induced autophagy and endothelial dysfunction

(2018) Xiangsheng Cai et al.   International Journal of Biological Sciences

Endosulfan induces autophagy and endothelial dysfunction via the AMPK/mTOR signaling pathway triggered by oxidative stress

(2017) Lianshuang Zhang et al.   ENVIRONMENTAL POLLUTION

Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation

(2016) Gibok Lee et al.   Scientific Reports

Knockdown of HIF-1α and IL-8 induced apoptosis of hepatocellular carcinoma triggers apoptosis of vascular endothelial cells

(2015) Sung Hoon Choi et al.   APOPTOSIS

Hypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed Cells

(2015) Shuyang Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia

(2014) Nathalie M. Mazure et al.   Autophagy

The Vascular Endothelium and Human Diseases

(2014) Peramaiyan Rajendran et al.   International Journal of Biological Sciences

Distinct Phenotypes of Human Prostate Cancer Cells Associate with Different Adaptation to Hypoxia and Pro-Inflammatory Gene Expression

(2014) Linda Ravenna et al.   PLoS One

ROS-mediated activation of AKT induces apoptosis via pVHL in prostate cancer cells

(2013) Mahandranauth A. Chetram et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

(2012) R. C. Wang et al.   SCIENCE

HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs

(2010) C Muller et al.   CELL DEATH AND DIFFERENTIATION

Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation

(2009) J. F. Garvey et al.   EUROPEAN RESPIRATORY JOURNAL

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

XRASGRP2 expression during early development of Xenopus embryos

(2008) Kentaro Nagamine et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS