Uncovering hidden therapeutic indications through drug repurposing with graph neural networks and heterogeneous data

DDI-GCN: Drug-drug interaction prediction via explainable graph convolutional networks

(2023) Yi Zhong et al.   Artificial Intelligence in Medicine

REDDA: Integrating multiple biological relations to heterogeneous graph neural network for drug-disease association prediction

(2022) Yaowen Gu et al.   COMPUTERS IN BIOLOGY AND MEDICINE

A computational approach to drug repurposing using graph neural networks

(2022) Siddhant Doshi et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Graph representation learning in biomedicine and healthcare

(2022) Michelle M. Li et al.   Nature Biomedical Engineering

Effect of add-on sacubitril/valsartan on the left ventricular hypertrophy of a patient with hypertension

(2022) Teruhiko Imamura et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Predicting Drug-Target Interactions Over Heterogeneous Information Network

(2022) Xiaorui Su et al.   IEEE Journal of Biomedical and Health Informatics

Application of network link prediction in drug discovery

(2021) Khushnood Abbas et al.   BMC BIOINFORMATICS

The JAK–STAT pathway: an emerging target for cardiovascular disease in rheumatoid arthritis and myeloproliferative neoplasms

(2021) Chiara Baldini et al.   EUROPEAN HEART JOURNAL

Current and future status of JAK inhibitors

(2021) Donal P McLornan et al.   LANCET

Integrating heterogeneous data to facilitate COVID-19 drug repurposing

(2021) Lucía Prieto Santamaría et al.   DRUG DISCOVERY TODAY

Drug repurposing for COVID-19 using graph neural network and harmonizing multiple evidence

(2021) Kanglin Hsieh et al.   Scientific Reports

Relation-aware Heterogeneous Graph Transformer based drug repurposing

(2021) Xin Mei et al.   EXPERT SYSTEMS WITH APPLICATIONS

Pathophysiology of Hypertensive Heart Disease: Beyond Left Ventricular Hypertrophy

(2020) Chike C. Nwabuo et al.   CURRENT HYPERTENSION REPORTS

DISNET: a framework for extracting phenotypic disease information from public sources

(2020) Gerardo Lagunes-García et al.   PeerJ

Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2

(2020) Yadi Zhou et al.   Cell Discovery

Repurpose Open Data to Discover Therapeutics for COVID-19 Using Deep Learning

(2020) Xiangxiang Zeng et al.   JOURNAL OF PROTEOME RESEARCH

JAK-Inhibitors for the Treatment of Rheumatoid Arthritis: A Focus on the Present and an Outlook on the Future

(2020) Jacopo Angelini et al.   Biomolecules

Deep Learning on Graphs: A Survey

(2020) Ziwei Zhang et al.   IEEE TRANSACTIONS ON KNOWLEDGE AND DATA ENGINEERING

A global network of biomedical relationships derived from text

(2018) Bethany Percha et al.   BIOINFORMATICS

Modeling polypharmacy side effects with graph convolutional networks

(2018) Marinka Zitnik et al.   BIOINFORMATICS

Early Diagnosis and Treatment of Rheumatoid Arthritis

(2018) Emily A. Littlejohn et al.   PRIMARY CARE

Drug repurposing: progress, challenges and recommendations

(2018) Sudeep Pushpakom et al.   NATURE REVIEWS DRUG DISCOVERY

Sacubitril/valsartan: beyond natriuretic peptides

(2017) Jagdeep S S Singh et al.   HEART

Geometric Deep Learning: Going beyond Euclidean data

(2017) Michael M. Bronstein et al.   IEEE SIGNAL PROCESSING MAGAZINE

A standard database for drug repositioning

(2017) Adam S. Brown et al.   Scientific Data

Janus kinase inhibitors for rheumatoid arthritis

(2016) Kunihiro Yamaoka   CURRENT OPINION IN CHEMICAL BIOLOGY

Immunological Consequences of JAK Inhibition: Friend or Foe?

(2015) Donal P. McLornan et al.   Current Hematologic Malignancy Reports

SemFunSim: A New Method for Measuring Disease Similarity by Integrating Semantic and Gene Functional Association

(2014) Liang Cheng et al.   PLoS One

Discovering disease-disease associations by fusing systems-level molecular data

(2013) Marinka Žitnik et al.   Scientific Reports

Update 2011: leflunomide in rheumatoid arthritis – strengths and weaknesses

(2011) Frank Behrens et al.   CURRENT OPINION IN RHEUMATOLOGY

Prevalence of left-ventricular hypertrophy in hypertension: an updated review of echocardiographic studies

(2011) C Cuspidi et al.   JOURNAL OF HUMAN HYPERTENSION

Metabolism and Excretion of the Once-Daily Human Glucagon-Like Peptide-1 Analog Liraglutide in Healthy Male Subjects and Its In Vitro Degradation by Dipeptidyl Peptidase IV and Neutral Endopeptidase

(2010) M. Malm-Erjefalt et al.   DRUG METABOLISM AND DISPOSITION

Rheumatoid arthritis

(2010) David L Scott et al.   LANCET

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Estimating classification error rate: Repeated cross-validation, repeated hold-out and bootstrap

(2009) Ji-Hyun Kim   COMPUTATIONAL STATISTICS & DATA ANALYSIS

A Translational Approach to Hypertensive Heart Disease

(2009) Javier Díez et al.   HYPERTENSION

Molecular, pharmacological and clinical aspects of liraglutide, a once-daily human GLP-1 analogue

(2008) D RUSSELLJONES   MOLECULAR AND CELLULAR ENDOCRINOLOGY