期刊
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
卷 -, 期 -, 页码 -出版社
BMJ PUBLISHING GROUP
DOI: 10.1136/archdischild-2023-325970
关键词
intensive care units, neonatal; intensive care units, paediatric; paediatrics; neonatology
类别
The survival rate of very preterm babies has increased, but they may still face ongoing morbidity. Most babies born before 32 weeks who are discharged home from neonatal care do not require admission to PICU in the first two years, but the risk is higher for those born very preterm or with significant neonatal morbidity.
Objective Survival of babies born very preterm (<32 weeks gestational age) has increased, although preterm-born children may have ongoing morbidity. We aimed to investigate the risk of admission to paediatric intensive care units (PICUs) of children born very preterm following discharge home from neonatal care.Design Retrospective cohort study, using data linkage of National Neonatal Research Database and the Paediatric Intensive Care Audit Network datasets.Setting All neonatal units and PICUs in England and Wales.Patients Children born very preterm between 1 January 2013 and 31 December 2018 and admitted to neonatal units.Main outcome measures Admission to PICU after discharge home from neonatal care, before 2 years of age.Results Of the 40 690 children discharged home from neonatal care, there were 2308 children (5.7%) with at least one admission to PICU after discharge. Of these children, there were 1901 whose first PICU admission after discharge was unplanned.The percentage of children with unplanned PICU admission varied by gestation, from 10.2% of children born <24 weeks to 3.3% born at 31 weeks. Following adjustment, unplanned PICU admission was associated with lower gestation, male sex (adjusted OR (aOR) 0.79), bronchopulmonary dysplasia (aOR 1.37), necrotising enterocolitis requiring surgery (aOR 1.39) and brain injury (aOR 1.42). For each week of increased gestation, the aOR was 0.90.Conclusions Most babies born <32 weeks and discharged home from neonatal care do not require PICU admission in the first 2 years. The odds of unplanned admissions to PICU were greater in the most preterm and those with significant neonatal morbidity.
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