Polyphyllin I, a strong antifungal compound against Candida albicans

Polyphyllin I Effects Candida albicans via Inhibition of Virulence Factors

(2023) Ai-Mei Sun et al.   Evidence-based Complementary and Alternative Medicine

Antifungal effects of alantolactone on Candida albicans: An in vitro study

(2022) Longfei Yang et al.   BIOMEDICINE & PHARMACOTHERAPY

Polyphyllin I Promotes Autophagic Cell Death and Apoptosis of Colon Cancer Cells via the ROS-Inhibited AKT/mTOR Pathway

(2022) Qihui Luo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Polyphyllin I improves myocardial damage in coronary artery disease via modulating lipid metabolism and myocardial apoptosis

(2022) Zhao Yang et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways

(2022) Françios A.B. Olivier et al.   Cell Reports

Antifungal drug-resistance mechanisms in Candida biofilms

(2022) Jaspreet Kaur et al.   CURRENT OPINION IN MICROBIOLOGY

The comparison analysis of polyphyllin I and its analogues induced apoptosis of colon and lung cancer cells via mitochondrial dysfunction

(2021) Li‐Jiao You et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Polyphyllin I reverses the resistance of osimertinib in non-small cell lung cancer cell through regulation of PI3K/Akt signaling

(2021) Lei Lai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Exploring the effect of Polyphyllin I on hepatitis B virus-related liver cancer through network pharmacology and in vitro experiments

(2021) Shuxian Yu et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Spilanthol as a promising antifungal alkylamide for the treatment of vulvovaginal candidiasis

(2021) Rodrigo L Fabri et al.   MEDICAL MYCOLOGY

Polyphyllin I, a lethal partner of Palbociclib, suppresses non-small cell lung cancer through activation of p21/CDK2/Rb pathway in vitro and in vivo

(2021) Zhengchao Shen et al.   CELL CYCLE

The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin

(2021) Martin Hoenigl et al.   DRUGS

Carnosol inhibits the growth and biofilm of Candida albicans

(2021) Longfei Yang et al.   JOURNAL DE MYCOLOGIE MEDICALE

Dihydroartemisinin Sensitizes Mutant p53 (R248Q)-Expressing Hepatocellular Carcinoma Cells to Doxorubicin by Inhibiting P-gp Expression

(2020) Yue Yang et al.   Biomed Research International

Underlying mechanisms of apoptosis in HepG2 cells induced by polyphyllin I through Fas death and mitochondrial pathways

(2020) Yawen Zeng et al.   TOXICOLOGY MECHANISMS AND METHODS

Polyphyllin I Promoted Melanoma Cells Autophagy and Apoptosis via PI3K/Akt/mTOR Signaling Pathway

(2020) Jianwen Long et al.   Biomed Research International

Polyphyllin I suppresses proliferation and promotes apoptosis of gastric cancer cell by inhibiting stat3 phosphorylation

(2020) Jun Han et al.   Translational Cancer Research

UHPLC-qMS spectrum-effect relationships for Rhizoma Paridis extracts

(2020) Xin Qiao et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Polyphyllin I induces cell cycle arrest in prostate cancer cells via the upregulation of IL6 and P21 expression

(2019) Denglu Zhang et al.   MEDICINE

Anti-cancer effects of Polyphyllin I: An update in 5 years

(2019) Ye Tian et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Antifungal Effects of Saponin Extract from Rhizomes of Dioscorea panthaica Prain et Burk against Candida albicans

(2018) Longfei Yang et al.   Evidence-based Complementary and Alternative Medicine

Invasive candidiasis

(2018) Peter G. Pappas et al.   Nature Reviews Disease Primers

Polyphyllin I Inhibits Propionibacterium acnes-Induced Inflammation In Vitro

(2018) Tingting Zhu et al.   INFLAMMATION

Polyphyllin I suppresses the formation of vasculogenic mimicry via Twist1/VE-cadherin pathway

(2018) Ting Xiao et al.   Cell Death & Disease

Polyphyllin I Ameliorates Collagen-Induced Arthritis by Suppressing the Inflammation Response in Macrophages Through the NF-κB Pathway

(2018) Qiong Wang et al.   Frontiers in Immunology

Dioscin Inhibits Virulence Factors of Candida albicans

(2018) Longfei Yang et al.   Biomed Research International

Antifungal Compounds against Candida Infections from Traditional Chinese Medicine

(2017) Xin Liu et al.   Biomed Research International

Anti-biofilm mechanisms of 3,5-di-tert-butylphenol against clinically relevant fungal pathogens

(2016) Janarthanam Rathna et al.   BIOFOULING

Candida albicans Hypha Formation and Mannan Masking of β-Glucan Inhibit Macrophage Phagosome Maturation

(2014) Judith M. Bain et al.   mBio

High-Throughput Screening of a Collection of Known Pharmacologically Active Small Compounds for Identification of Candida albicans Biofilm Inhibitors

(2013) Samuel A. Siles et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effects of polyphyllin I on growth inhibition of human non-small lung cancer cells and in xenograft

(2010) M. Kong et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA