Article
Obstetrics & Gynecology
Olga Bougie, Jessica Blom, Grace Zhou, Ally Murji, Jackie Thurston
Summary: Postoperative opioid use following gynecologic surgery may lead to side effects and negative health consequences. Strategies such as adherence to Enhanced Recovery After Surgery Protocols and multimodal analgesia management can help decrease the need for opioid use.
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
(2022)
Article
Medicine, General & Internal
Peter Pockney, Aya Basam, Liam Ferguson, Lorane Gaborit, Sarah Goh, Amie Hilde, Aiden Jabur, Kaviya Kalyanasundaram, Chui Foong (Kelly) Ong, Melissa Park, Upasana Pathak, Kyle Raubenheimer, Venesa Siribaddana, Chris Varghese, Jennifer Vu, Cameron Wells, William Xu, Ademola Adeyeye, Luis Adrian Alvarez-Lozada, Simran Vinod Benyani, Milos Buhavac, Giacomo Calini, Davina Daudu, Semra Demirli Atici, Mustafa Deniz Tepe, Muhammed Elhadi, Orestis Ioannidis, Nandini Karthikeyan, Laure Taher Mansour, Upanmanyu Nath, Warren Seow, Surya Singh, Zoya Tasi, Ahmad Uzair, Wah Yang, Faseeh Zaidi, Kristy Atherton, Arnab Banerjee, Amanda Dawson, Nagendra Dudi-Venkata, Nicholas Lightfoot, Isabella Ludbrook, Jennifer Martin, Luke Peters, Toby Richards, Rachel Sara, David Watson, Deborah Wright
Summary: This study aims to investigate the prescription and consumption of opioids at 7 days postdischarge after surgery and their impact on patients' postoperative pain.
Article
Medicine, General & Internal
Felix C. B. Lindeberg, Max Bell, Emma Larsson, Linn Hallqvist
Summary: This cohort study aimed to describe the frequency of new prolonged opioid consumption after major surgery in Sweden and identify associated risk factors. The study included data from 216,877 patients from 23 Swedish hospitals. The results showed that 7% of patients developed new prolonged opioid consumption after major surgery, with a history of psychiatric disease being the strongest risk factor.
Article
Cardiac & Cardiovascular Systems
William Z. Chancellor, J. Hunter Mehaffey, Raj P. Desai, Jared Beller, Rajesh Balkrishnan, Dustin M. Walters, Linda W. Martin
Summary: This study found that chronic and prolonged opioid use is significantly associated with lower long-term survival rates after lung cancer resection. These results further support a biological relationship between opioid use and lung cancer progression.
ANNALS OF THORACIC SURGERY
(2021)
Article
Clinical Neurology
Christopher Kowalski, Ryan Ridenour, Sarah McNutt, Djibril Ba, Guodong Liu, Jesse Bible, Michael Aynardi, Matthew Garner, Douglas Leslie, Aman Dhawan
Summary: This retrospective study evaluated factors associated with prolonged post-operative opioid pain medication usage following spine surgery, as well as the risk of post-operative complications associated with pre-operative opioid usage. The study found that pre-operative narcotic use and certain comorbidities were associated with prolonged post-operative opioid usage. This data provides important information for spine surgeons in determining post-operative analgesia strategies.
GLOBAL SPINE JOURNAL
(2023)
Article
Obstetrics & Gynecology
Caroline K. Heres, Noah B. Rindos, Isabel R. Fulcher, Sarah E. Allen, Nathan R. King, Shana M. Miles, Nicole M. Donnellan
Summary: The study aimed to quantify postoperative opioid use after laparoscopic surgery for endometriosis or pelvic pain, and identify patient characteristics associated with greater postoperative opioid requirements. Results showed that most patients had a lower postoperative opioid requirement than prescribed, suggesting surgeons can prescribe fewer postoperative narcotics in this population. Patients with a previous surgery for pelvic pain, self-reported chronic pelvic pain syndrome, anxiety, and depression may represent a subset of patients with increased postoperative opioid requirements.
JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Kevin M. Turner, Aaron M. Delman, Azante Griffith, Koffi Wima, Taylor E. Wallen, Sandra L. Starnes, Bradley M. Budde, Robert M. Van Haren
Summary: The study aimed to evaluate the effects of enhanced recovery after surgery (ERAS) on long-term opioid use. The results showed that although ERAS reduced opioid use in the short-term, there was no change in long-term opioid use. Additional strategies are urgently needed to monitor and prevent dependence on opioids after pulmonary resection.
ANNALS OF THORACIC SURGERY
(2023)
Article
Anesthesiology
Jill A. Hayden, Jenna Ellis, Mark Asbridge, Rachel Ogilvie, Roah Merdad, D. A. Gus Grant, Samuel A. Stewart, Samuel Campbell
Summary: Low back pain is a common reason for emergency department visits where opioids are often prescribed. This study found that older age and female sex were associated with increased odds of prolonged opioid use among opioid-naive adults with low back pain. Higher initial prescription doses and longer supply durations were also linked to prolonged opioid use. The study suggests a cautious approach to prescribing opioids for opioid-naive populations.
Article
Clinical Neurology
Peter Uhrbrand, Peter Helmig, Simon Haroutounian, Simon Tilma Vistisen, Lone Nikolajsen
Summary: Patients continue to use opioids after spine surgery for reasons beyond surgery-related pain. Withdrawal symptoms are common within the first 3 months post-surgery and are linked to failure to discontinue opioid treatment. Half of the patients seek healthcare for pain-related issues in the first 3 months after discharge.
Article
Clinical Neurology
Peter Uhrbrand, Peter Helmig, Simon Haroutounian, Simon Tilma Vistisen, Lone Nikolajsen
Summary: This study found that patients continue to use opioids after spine surgery not only for surgery-related pain, but also for other reasons. Withdrawal symptoms were experienced by about one-third of patients in the first three months post-surgery, and were associated with failure to discontinue opioid treatment. Half of the patients contacted healthcare providers within the first three months after discharge seeking pain-related care.
Article
Surgery
Charles Katzman, Emily C. Harker, Rizwan Ahmed, Charles A. Keilin, Joceline V. Vu, David C. Cron, Vidhya Gunaseelan, Yen-Ling Lai, Chad M. Brummett, Michael J. Englesbe, Jennifer F. Waljee
Summary: The study showed that patients with nonchronic, periodic preoperative opioid use are more likely to have prolonged postoperative opioid use. Identifying opioid use before surgery presents a critical opportunity to optimize care after surgery.
Article
Medicine, General & Internal
Jiayi Gong, Alan Forbes Merry, Kebede A. Beyene, Doug Campbell, Chris Frampton, Peter Jones, John McCall, Matthew Moore, Amy Hai Yan Chan
Summary: Opioid use for chronic non-cancer-related pain has increased globally, with concerns about misuse and subsequent harm. This study in New Zealand aims to describe rates and predictors of persistent opioid use following hospital discharge for surgery or trauma among opioid-naive individuals. The study will use linked national health administrative databases and employ logistic regression and Cox regression models to identify predictors and estimate risks of opioid-related harms and hospitalisation. Ethical approval has been obtained and results will be reported following RECORD guidelines.
Article
Surgery
Teryn A. Holeman, Michael J. Buys, Kimberlee Bayless, Zachary Anderson, Julie Hales, Benjamin S. Brooke
Summary: This study aimed to evaluate the impact of complete opioid tapering after surgery on pain intensity and pain interference. The study found significant improvement in pain intensity and interference among patients who completely tapered off opioids after surgery, especially among those undergoing orthopedic procedures early after surgical discharge.
Article
Surgery
Brittany E. Levy, Jennifer T. Castle, Laura M. Ebbitt, Caleb Kennon, Erin McAtee, Daniel L. Davenport, B. Mark Evers, Avinash Bhakta
Summary: This retrospective study analyzed elective colorectal resections performed by a fellowship-trained colorectal surgeon from January 2013 to December 2020. The results showed that post-discharge opioid use was not predicted or influenced by perioperative analgesic procedures. This indicates that preoperative risk factors should be considered when prescribing discharge opioid medications.
JOURNAL OF SURGICAL RESEARCH
(2023)
Article
Surgery
Ryan Howard, Andrew Ryan, Hsou Mei Hu, Craig S. Brown, Jennifer Waljee, Mark C. Bicket, Michael Englesbe, Chad M. Brummett
Summary: This study aims to evaluate the association between evidence-based opioid prescribing guidelines and new persistent opioid use after surgery. Using Medicare claims, the study compared opioid-naive patients who underwent surgery in Michigan, where evidence-based guidelines were released, with those who underwent surgery outside of Michigan. The results showed a significant reduction in the incidence of new persistent opioid use and the quantity of opioids prescribed after the release of the guidelines.