4.7 Article

Regioselective electrophilic borylation of haloarenes

期刊

CHEMICAL COMMUNICATIONS
卷 51, 期 14, 页码 2878-2881

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc10153g

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资金

  1. ERC [305868]
  2. Conacyt [311311]
  3. Royal Society
  4. EPSRC [EP/K039547/1]
  5. European Research Council (ERC) [305868] Funding Source: European Research Council (ERC)
  6. Engineering and Physical Sciences Research Council [EP/K039547/1] Funding Source: researchfish
  7. EPSRC [EP/K039547/1] Funding Source: UKRI

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Haloarenes undergo direct borylation using amine : BCl3:AlCl3 in the ratio of 1 : 1 : 2. After esterification the pinacol boronate esters are isolated in good yield with regioselectivity controlled by steric and electronic effects.

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