Article
Chemistry, Multidisciplinary
Xinjie Wei, Xuan Luo, Shuai Xu, Fengna Xi, Tingting Zhao
Summary: Fast, convenient, and highly sensitive detection of antibiotics is crucial to prevent their overuse and potential harm. In this study, a flexible electrochemiluminescence (ECL) sensor based on vertically ordered mesoporous silica nanochannel film (VMSF) was developed for sensitive detection of clindamycin. The sensor exhibited high signal stability and antifouling characteristic, allowing direct analysis of clindamycin in real biological samples.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Haiyun Chen, Jie Huang, Rongjing Zhang, Fei Yan
Summary: In this study, the highly sensitive detection of alphafetoprotein (AFP) was achieved using electrochemiluminescence and electrochemistry. The utilization of vertically ordered mesoporous silica films as a sensing interface resulted in a signal amplification effect and excellent sensitivity. The dual-mode detection of AFP showed a low limit of detection and a wide linear range, with satisfactory results obtained in the analysis of human serum.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Analytical
Yi Xiao, Suhua Chen, Simeng Zhang, Guofang Wang, Haomin Yi, Gui-Zhong Xin, Xiaoping Yang
Summary: This study presents a mesoporous silica-mediated controllable electrochemiluminescence quenching immunosensor for straightforward and accurate measurement of immunological biomarkers. The sensitivity can be enhanced and the detection range can be broadened by tuning the ECL quenching, offering a new avenue for physiological and clinical implications of immunological biomarkers with a wide range of applications.
Article
Chemistry, Analytical
Rong Tan, Yueju Wang, Xiaona Mi, Huiling Li, Yifeng Tu
Summary: This study presents a novel dual-screening sensing strategy based on specific aptamer recognition and mesoporous silica membrane (MSM) nano-sieving for the detection of A/3, which enhances the specificity and sensitivity of detection, aiding in monitoring the occurrence and development of Alzheimer's disease.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Multidisciplinary
Zisan Zeng, Yang Zhao, Luoxing Yang, Fengna Xi, Danke Su
Summary: In this study, a label-free and sensitive electrochemical cytosensor was developed for the detection of HeLa cells. The cytosensor utilizes vertically ordered mesoporous silica films and specific recognition of folic acid for quantitative determination of HeLa cells with a broad linear range and low detection limit.
FRONTIERS IN CHEMISTRY
(2023)
Article
Chemistry, Analytical
Sudarat Sombatsri, Krittanun Deekamwong, Pongtanawat Khemthong, Sanchai Prayoonpokarach
Summary: An optical sensor was developed based on pyranine immobilized on aminopropyl-modified mesoporous silica films for the detection of paraquat in aqueous solutions. The films were deposited on fluorine-doped tin oxide glass using an electrochemically assisted self-assembly method. The fluorescence signal of the immobilized films was quenched in the presence of paraquat. The films modified with 3% APTES showed the optimum response to paraquat.
Article
Chemistry, Multidisciplinary
Kai Ma, Yanyan Zheng, Lizhe An, Jiyang Liu
Summary: This study demonstrates a novel electroluminescence immunoassay platform based on vertically ordered mesoporous silica-nanochannel films for ultrasensitive detection of prostate-specific antigen (PSA) in human serum.
FRONTIERS IN CHEMISTRY
(2022)
Article
Nanoscience & Nanotechnology
Qian Wang, Zuhao Zhang, Lu Zhang, Yunqing Liu, Li Xie, Shenguang Ge, Jinghua Yu
Summary: In this work, a CRISPR/Cas12a initiated switchable ternary electrochemiluminescence (ECL) biosensor combined with a Co3O4@Au nanoemitter is presented for the in vitro monitoring of miRNA-141. The biosensor demonstrated extraordinary sensitivity and specificity, with a low detection limit.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Jiawei Gong, Hongliang Tang, Xuan Luo, Huaxu Zhou, Xueting Lin, Kailong Wang, Fei Yan, Fengna Xi, Jiyang Liu
Summary: A novel ECL sensing platform based on VMSF and 3DG was developed in this study, showing high sensitivity for detecting environmental pollutants and pharmaceuticals with excellent antifouling ability. This sensor may open new avenues for the development of highly sensitive ECL sensing platforms.
FRONTIERS IN CHEMISTRY
(2021)
Article
Materials Science, Ceramics
Naiqiang Yin, Xianling Wang, Tonghui Yang, Yanli Ding, Liqiang Li, Shihua Zhao, Peng Li, Xiaoliang Xu, Lixin Zhu
Summary: This study developed a uniform and multifunctional nanoplatform probe with excellent magnetic, fluorescent, and photothermal properties for various medical applications. By embedding QDs into mesoporous silica, the probe successfully internalized into cancer cells, demonstrating precise fluorescence labelling and cancer cell destruction behavior.
CERAMICS INTERNATIONAL
(2021)
Article
Chemistry, Analytical
Jiawei Guo, Xiuli Liu, Aizhu Wang, Xin Yu, Longhua Ding
Summary: An efficient antifouling electrochemical sensor was developed by coating a mesoporous silica film on a graphene oxide/glass carbon electrode. This sensor exhibited excellent response to imidacloprid and could directly determine it in untreated carthamus tinctorius.
MICROCHEMICAL JOURNAL
(2022)
Article
Electrochemistry
Mohammad Ali Kamyabi, Zahra Alipour, Mohsen Moharramnezhad
Summary: A new feasible method for the determination of amoxicillin using electrochemiluminescence (ECL) was developed, with a modified ZnO nanoparticle/nickel foam electrode. The fabricated electrode showed high sensitivity and was applied for trace analysis of amoxicillin in alkaline solutions. The proposed ECL-based sensor demonstrated superior proficiency for accurate analysis of amoxicillin, with high selectivity and excellent repeatability.
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
(2021)
Article
Biophysics
Hassan Nasrollahpour, Mahdi Mahdipour, Ibrahim Isildak, Mohammad-Reza Rashidi, Abdolhosein Naseri, Balal Khalilzadeh
Summary: The study developed an ECL-based cytosensor for quantifying metastatic breast cancer cells, utilizing silica-based mesoporous materials for electrode preparation. The sensor showed good specificity and repeatability, making it suitable for clinical applications in combination with microfluidic systems for the detection and separation of metastatic cells.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Terefe Tafese Bezuneh, Tadesse Haile Fereja, Shimeles Addisu Kitte, Haijuan Li, Yongdong Jin
Summary: This article summarizes the development and application of electrogenerated chemiluminescence (ECL) biosensors based on gold nanoparticles (Au NPs) signal amplification strategies. Au NPs can significantly enhance the performance of ECL biosensors through various approaches. These sensors can be used for the detection of proteins, metal ions, nucleic acids, small molecules, living cells, exosomes, and cell imaging.
Article
Chemistry, Analytical
Xue Dong, Qingze Zeng, Li Dai, Xiang Ren, Wei Cao, Huangxian Ju, Qin Wei
Summary: In this study, a novel signal on-amplified-off detection mode for progesterone (P4) was proposed, utilizing hafnium oxide (HfO2) as an electrochemiluminescence (ECL) emitter and Ni-doped ZnO (Ni-ZnO) as a coreaction accelerator. The P4 analysis using this strategy significantly improved sensitivity and specificity, offering a practical method for biomolecule detection beyond the scope of this study.
ANALYTICAL CHEMISTRY
(2023)
Article
Oncology
Jingshun Gu, Xuehua Ge, Aiwu You, Jun Li, Yuyan Zhang, Guomin Rao, Juntong Wang, Kun Zhang, Xuan Liu, Xiaotang Wu, Ling Cheng, Mengjiao Zhu, Dongchun Wang
Summary: Studies have shown that miR-218-5p is negatively associated with TCF12 in gliomas, with low expression correlating with poor prognosis. Experimental validation confirmed the regulatory role of miR-218-5p in glioma cells.
Article
Astronomy & Astrophysics
Guoying Zhao, Zhaosheng Li, Yuanyue Pan, Maurizio Falanga, Long Ji, Yupeng Chen, Shu Zhang
Summary: Type I X-ray bursts are the result of unstable thermonuclear burning on the surface of a neutron star, resulting in the release of energetic X-ray photons. These bursts interact with the surrounding accretion disk, increasing the accretion rate. By analyzing two photospheric radius expansion bursts in 4U 1636-536, it was found that the spectral fitting can be improved by considering enhanced persistent emission or reflection from the accretion disk. Evidence suggests that both Poynting-Robertson drag and disk reflection occurred during these bursts, and the disk reflection may contribute up to 20-30% of the total burst emissions.
ASTRONOMY & ASTROPHYSICS
(2022)
Article
Astronomy & Astrophysics
Xiaobo Li, Mingyu Ge, Lin Lin, Shuang-Nan Zhang, Liming Song, Xuelei Cao, Bing Zhang, Fangjun Lu, Yupeng Xu, Shaolin Xiong, Youli Tuo, Ying Tan, Weichun Jiang, Jinlu Qu, Shu Zhang, Lingjun Wang, Jieshuang Wang, Binbin Zhang, Peng Zhang, Chengkui Li, Congzhan Liu, Tipei Li, Qingcui Bu, Ce Cai, Yong Chen, Yupeng Chen, Zhi Chang, Li Chen, Tianxiang Chen, Yibao Chen, Weiwei Cui, Yuanyuan Du, Guanhua Gao, He Gao, Yudong Gu, Ju Guan, Chengcheng Guo, Dawei Han, Yue Huang, Jia Huo, Shumei Jia, Jing Jin, Lingda Kong, Bing Li, Gang Li, Wei Li, Xian Li, Xufang Li, Zhengwei Li, Xiaohua Liang, Jinyuan Liao, Hexin Liu, Hongwei Liu, Xiaojing Liu, Xuefeng Lu, Qi Luo, Tao Luo, Binyuan Ma, Ruican Ma, Xiang Ma, Bin Meng, Yi Nang, Jianyin Nie, Ge Ou, Xiaoqin Ren, Na Sai, Xinying Song, Liang Sun, Lian Tao, Chen Wang, Pengju Wang, Wenshuai Wang, Yusa Wang, Xiangyang Wen, Bobing Wu, Baiyang Wu, Mei Wu, Shuo Xiao, Sheng Yang, Yanji Yang, Qibin Yi, Qianqing Yin, Yuan You, Wei Yu, Fan Zhang, Hongmei Zhang, Juan Zhang, Wanchang Zhang, Wei Zhang, Yifei Zhang, Yuanhang Zhang, Haisheng Zhao, Xiaofan Zhao, Shijie Zheng, Dengke Zhou
Summary: This study reports the detection of a strong quasi-periodic oscillation (QPO) of about 40 Hz in an X-ray burst from the magnetar SGR J1935+2154, which is associated with FRB 200428. The discovery suggests that some FRBs may be related to strong oscillation processes of neutron stars, providing important clues for understanding the origin and mechanism of FRBs.
ASTROPHYSICAL JOURNAL
(2022)
Article
Business
Li Gao, Gang Li, Fusheng Tsai, Chen Gao, Mengjiao Zhu, Xiaopian Qu
Summary: This article analyzes the effects of AI stimuli on customer engagement and value co-creation, and examines the moderating role of customer ability readiness. The study found that perceived interactivity of AI stimuli has a positive impact on value co-creation, customer engagement mediates the relationship between perceived interactivity and value co-creation, and customer ability readiness moderates the relationship between AI stimuli, customer engagement, and value co-creation.
JOURNAL OF RESEARCH IN INTERACTIVE MARKETING
(2023)
Article
Astronomy & Astrophysics
Yu-Peng Chen, Jian Li, Shao-Lin Xiong, Long Ji, Shu Zhang, Wen-Xi Peng, Rui Qiao, Xin-Qiao Li, Xiang-Yang Wen, Li-Ming Song, Shi-Jie Zheng, Xin-Ying Song, Xiao-Yun Zhao, Yue Huang, Fang-Jun Lu, Shuang-Nan Zhang, Shuo Xiao, Ce Cai, Zheng-Hua An, Zhi Chang, Can Chen, Gang Chen, Wei Chen, Guang-Qi Dai, Yan-Qi Du, Min Gao, Ke Gong, Dong-Ya Guo, Zhi-Wei Guo, Jian-Jian He, Bin Li, Chao Li, Chao-Yang Li, Gang Li, Jian-Hui Li, Lu Li, Qing-Xin Li, Xiao-Bo Li, Yan-Guo Li, Jing Liang, Xiao-Hua Liang, Jin-Yuan Liao, Jia-Cong Liu, Xiao-Jing Liu, Ya-Qing Liu, Qi Luo, Xiang Ma, Bin Meng, Ge Ou, Dong-Li Shi, Jing-Yan Shi, Gong-Xing Sun, Xi-Lei Sun, You-Li Tuo, Chen-Wei Wang, Hui Wang, Huan-Yu Wang, Jin Wang, Jin-Zhou Wang, Ping Wang, Wen-Shuai Wang, Yu-Xi Wang, Xing Wen, Hong Wu, Sheng-Lun Xie, Yan-Bing Xu, Yu-Peng Xu, Wang-Chen Xue, Sheng Yang, Min Yao, Jian-Ying Ye, Qi-Bin Yi, Cheng-Mo Zhang, Chao-Yue Zhang, Da-Li Zhang, Fan Zhang, Fei Zhang, Hong-Mei Zhang, Kai Zhang, Peng Zhang, Xiao-Lu Zhang, Yan-Qiu Zhang, Zhen Zhang, Guo-Ying Zhao, Shi-Yi Zhao, Yi Zhao, Chao Zheng, Xing Zhou, Yue Zhu
Summary: The translated text describes a bright thermonuclear X-ray burst observed from 4U 0614+09, including information about the time-resolved spectroscopy of the burst and the presence of burst oscillation. The findings support the spin frequency of the source and found consistent results with previous observations.
ASTROPHYSICAL JOURNAL
(2022)
Article
Plant Sciences
Ya Lv, Jun Chen, Mengjiao Zhu, Yishan Liu, Xiaoyuan Wu, Xin Xiao, Nana Yuyama, Fengxia Liu, Haichun Jing, Hongwei Cai
Summary: This study discovered a red leaf phenotype in sorghum and investigated the histological, metabolic, and transcriptomic aspects of the red leaves. The findings provide valuable insights into the genetic basis and metabolic regulation of the red leaf phenotype in sorghum.
Article
Astronomy & Astrophysics
Yu-Peng Chen, Shu Zhang, Long Ji, Shuang-Nan Zhang, Ling-Da Kong, Peng-Ju Wang, Zhi Chang, Jing-Qiang Peng, Jin-Lu Qu, Jian Li
Summary: This study investigates the interplay between a bright photospheric radius expansion (PRE) burst and persistent emission in 4U 1608-52. The findings indicate that the burst emission can be either enhanced preburst/persistent emission or the Comptonization of the burst emission by the corona/boundary layer. The temporal evolution of the NS surface emission shows a plateau and then a rise until the photosphere touches down on the NS surface, resulting in a flux peak.
ASTROPHYSICAL JOURNAL
(2022)
Article
Astronomy & Astrophysics
Zi-xu Yang, Liang Zhang, Yue Huang, Qingcui Bu, Zhen Zhang, He-Xin Liu, Wei Yu, Peng-Ju Wang, Q. C. Zhao, L. Tao, Jin-Lu Qu, Shu Zhang, Shuang-Nan Zhang, Liming Song, Fangjun Lu, Xuelei Cao, Li Chen, Ce Cai, Zhi Chang, Tianxiang Chen, Yong Chen, Yupeng Chen, Yibao Chen, Weiwei Cui, Guoqiang Ding, Yuanyuan Du, Guanhua Gao, He Gao, Mingyu Ge, Yudong Gu, Ju Guan, Chengcheng Guo, Dawei Han, Jia Huo, Shumei Jia, Weichun Jiang, Jing Jin, Lingda Kong, Bing Li, Gang Li, Wei Li, Xian Li, Xufang Li, Zhengwei Li, Chengkui Li, Lin Lin, Congzhan Liu, Tipei Li, Xiaobo Li, Xiaohua Liang, Jinyuan Liao, Hongwei Liu, Xiaojing Liu, Xuefeng Lu, Qi Luo, Tao Luo, Binyuan Ma, RuiCan Ma, Xiang Ma, Bin Meng, Yi Nang, Jianyin Nie, Ge Ou, Xiaoqin Ren, Na Sai, Xinying Song, Liang Sun, Ying Tan, Youli Tuo, Chen Wang, Wenshuai Wang, Lingjun Wang, Yusa Wang, Jieshuang Wang, Xiangyang Wen, Bobing Wu, Baiyang Wu, Mei Wu, Shuo Xiao, Yupeng Xu, Shaolin Xiong, Sheng Yang, Yanji Yang, Qibin Yi, Qianqing Yin, Yuan You, Bing Zhang, Fan Zhang, Hongmei Zhang, Juan Zhang, Wanchang Zhang, Wei Zhang, Binbin Zhang, Peng Zhang, Yifei Zhang, Yuanhang Zhang, Haisheng Zhao, Xiaofan Zhao, Shijie Zheng, Dengke Zhou
Summary: In this study, we report the spectral-timing results of the black hole X-ray binary 4U 1630-47 during its 2021 outburst using observations from the Hard X-ray Modulation Telescope. We detected Type C quasi-periodic oscillations (QPOs) and quasi-regular modulation (QRM) near 60 mHz, and found that the properties of the QRM phenomenon are energy-dependent and also related to the accretion rate.
ASTROPHYSICAL JOURNAL
(2022)
Article
Astronomy & Astrophysics
P. J. Wang, L. D. Kong, S. Zhang, V Doroshenko, A. Santangelo, L. Ji, E. S. Yorgancioglu, Y. P. Chen, S. N. Zhang, J. L. Qu, M. Y. Ge, J. Li, Z. Chang, L. Tao, J. Q. Peng, Q. C. Shui
Summary: In this study, timing analysis of the 2020 giant outburst of 1A 0535+262 using broadband data from Insight-HXMT is reported. The pulse profile evolution from the subcritical-luminosity to the supercritical-luminosity regime is presented for the first time. It is found that the observed pulse profile exhibits a complex dependence on both energy and luminosity, with a dip structure at the energy of the cyclotron resonant scattering features.
ASTROPHYSICAL JOURNAL
(2022)
Article
Astronomy & Astrophysics
Yu-Peng Chen, Shu Zhang, Long Ji, Shuang-Nan Zhang, Peng-Ju Wang, Ling-Da Kong, Zhi Chang, Jing-Qiang Peng, Qing-Cang Shui, Jian Li, Lian Tao, Ming-Yu Ge, Jin-Lu Qu
Summary: MAXI J1816-195 is a newly discovered accreting millisecond pulsar with peculiar characteristics, including a mild deviation from the conventional blackbody model and a detected hard X-ray shortage. Compared with other millisecond pulsars and atoll bursters, MAXI J1816-195 stands out as a rather unique system.
ASTROPHYSICAL JOURNAL LETTERS
(2022)
Article
Food Science & Technology
Yue Zhang, Mengjiao Zhu, Wenjing Lu, Cen Zhang, Di Chen, Nagendra P. Shah, Chaogeng Xiao
Summary: Using soybean sprouts as a fermentation substrate enhances the ability of Levilactobacillus brevis NPS-QW 145 strain to produce gamma-aminobutyric acid (GABA), a non-protein amino acid with various physiological functions. The study achieved a GABA yield of up to 2.302 g L-1 by fermenting monosodium glutamate (MSG) with L. brevis NPS-QW 145 for 48 hours using 10 g L-1 glucose, with a soybean germination time of one day. This research provides a powerful technique for GABA production in foods and its use as a nutritional supplement for consumers.
Article
Agronomy
Xin Xiao, Mengjiao Zhu, Yishan Liu, Jingru Zheng, Yiping Cui, Candong Xiong, Jiangjiang Liu, Jun Chen, Hongwei Cai
Summary: In this study, the seed shattering process in sorghum was investigated by examining the phenotypes of sorghum germplasm and analyzing the histology of the abscission zone. Through gene co-expression analysis, candidate genes involved in hormone signal transmission, cell wall modification and degradation, and lignin synthesis were identified. These findings provide insights into the understanding of the seed shattering process in sorghum.
Article
Neurosciences
Jun Li, Jingshun Gu, Juntong Wang, Aiwu You, Yuyan Zhang, Guomin Rao, Shuang Li, Xuehua Ge, Kun Zhang, Xiaotang Wu, Ling Cheng, Mengjiao Zhu, Dongchun Wang
Summary: This study found that miR-137 could inhibit the progression of glioma cells and promote their programmed cell death by targeting E2F7, providing insights into the search for new molecular therapeutic targets for glioma.
FOLIA NEUROPATHOLOGICA
(2022)
Article
Cell Biology
Haijing Wang, Disong Wang, Tingting Gu, Mengjiao Zhu, Ling Cheng, Wentao Dai
Summary: The study revealed that AADAC was upregulated in ovarian cancer tissues, and patients with high AADAC expression had better survival conditions. Overexpression of AADAC inhibited the malignant progression of ovarian cancer cells. Both cisplatin and imatinib showed inhibitory effects on cancer cells, which were synergistically enhanced by overexpressed AADAC.
HISTOLOGY AND HISTOPATHOLOGY
(2022)
Article
Urology & Nephrology
Wenqiang Fu, Haihong Zhao, Yifei Liu, Honglin Nie, Bin Gao, Feng Yin, Baocun Wang, Tengfei Li, Tingting Zhang, Lijuan Wang, Xiaotang Wu, Mengjiao Zhu, Lianjie Xia
Summary: The study showed that exosomes derived from cancer-associated fibroblasts (CAFs) can be internalized by clear-cell renal-cell carcinoma (ccRCC) cells, promoting proliferation, migration, and invasion of tumors, while inhibiting apoptosis. Furthermore, CAF-derived exosomes also increase the expression of metastasis-associated proteins in cancer cells and affect the cell cycle.
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)