Article
Biochemistry & Molecular Biology
Miroslaw Kasprzak, Agnieszka Szablowska, Agata Kurzyk, Paulina Tymowicz-Grzyb, Adrian Najmrodzki, Anna Wozniak, Agnieszka Antosik, Joanna Pagacz, Piotr Szterner, Andrzej Plichta, Piotr Wiecinski, Paulina Rusek-Wala, Agnieszka Krupa, Przemyslaw Plocinski, Karolina Rudnicka, Monika Biernat
Summary: Composites based on PLA and HA were prepared using a thermally induced phase separation method. The degradation and pore size distribution of the composites were affected by the preparation, sterilization, and incubation processes, as well as the addition of HA. The inclusion of HA reduced the degradation of PLA and showed no cytotoxicity, indicating its potential for biomedical applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Elias H. Arias-Nava, B. Patrick Sullivan, Delia J. Valles-Rosales
Summary: The study investigates the degradation mechanism of Polylactic Acid (PLA) through accelerated degradation testing of ASTM specimens, finding a significant impact of the independent variable time. The proposed statistical models can serve as a tool for characterizing the durability of biopolymer as an engineering material.
Article
Spectroscopy
Fang Wang, Zhu Nan, Xiaolin Sun, Chang Liu, Yan Zhuang, Jianan Zan, Chunfa Dai, Yunfei Liu
Summary: This paper investigates the degradation behavior of two kinds of PLA biodegradable materials and analyzes the correlation between material characteristics and degradation time through spectral analysis and statistical methods.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Materials Science, Multidisciplinary
Meng Ma, Xinpeng Wang, Kai Liu, Si Chen, Yanqin Shi, Huiwen He, Xu Wang
Summary: This paper presents a method for preparing flame-retardant and toughened PLA composites using reactive blending with in-situ formed polyurethane and ammonium polyphosphate. The addition of glycerin as a cross-linking agent improves the toughness of the composites and reduces their dropping behavior during combustion. The composites with 5% APP and 10% cross-linking degree exhibit balanced performance, achieving a V-2 level of vertical combustion and an elongation at break of about 200%.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Pei Feng, Jiye Jia, Mingyang Liu, Shuping Peng, Zhenyu Zhao, Cijun Shuai
Summary: This study systematically analyzed the degradation mechanisms and influencing factors of PLA bone scaffold, summarized strategies and mechanisms to accelerate degradation, and introduced the role of rapid prototyping technologies in scaffold structures.
MATERIALS & DESIGN
(2021)
Article
Environmental Sciences
Qiyu Qin, Yidi Yang, Changfu Yang, Leilihe Zhang, Haoyuan Yin, Fei Yu, Jie Ma
Summary: This study investigated the characteristics of biodegradable plastic PLA and its adsorption behavior with tetracycline under weathering conditions. The results showed that weathered PLA had cracks and holes on the surface, increased oxygen-containing functional groups, and enhanced adsorption capacity. However, the surface of microplastics weathered by seawater did not change significantly.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Polymer Science
Israel Garnica-Bohorquez, Viviana R. Guiza-Arguello, Clara I. Lopez-Gualdron
Summary: In order to successfully implement low-cost additive manufacturing (AM) techniques for custom medical device (MD) production, it is important to understand the impact of common and affordable sterilization processes such as formaldehyde or steam sterilization on AM-manufactured pieces. This research aimed to evaluate the effect of formaldehyde and steam sterilization on the dimensional and mechanical stability of standard polylactic acid (PLA) test pieces made by fused deposition modeling (FDM). Significant changes were found in mechanical and dimensional properties based on manufacturing parameters. This study contributes to the development of affordable approaches for functional and customized medical devices using AM technologies, particularly in low- and middle-income countries.
Article
Engineering, Biomedical
Sana Ullah, Hina Ghulam Ali, Motahira Hashmi, Md. Kaiser Haider, Tehmeena Ishaq, Yasushi Tamada, Soyoung Park, Ick Soo Kim
Summary: This study synthesized DNA-cationic surfactant complexes and blended them with a polylactic acid biopolymer to obtain nanofibers, on which copper nanoparticles were synthesized. The nanofibers showed uniform morphology and the copper nanoparticles exhibited uniform growth on them. The incorporation of DNA complexes improved the biocompatibility and antibacterial activity of the nanofibers.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2023)
Article
Chemistry, Physical
Francesca Agostinacchio, Devid Maniglio, Emanuela Callone, Claudio Migliaresi, Sandra Dire, Antonella Motta
Summary: By selectively and controllably enzymatically attacking silk fibroin, a lower molecular weight fibroin-derived material can be created with tunable molecular weight and secondary structure. The cleavage results in a material with increased reactivity and good stability in water.
Article
Multidisciplinary Sciences
O. J. Gbadeyan, L. Z. Linganiso, N. Deenadayalu
Summary: This study focuses on the thermomechanical investigation of bioplastic firms produced from a combination of polylactic acid (PLA) and nano-calcium carbonated (nano-CaCO3) synthesized from the Achatina Fulica snail shell. It was observed that incorporating nano-CaCO3 improved the thermal stability and temperature-dependent mechanical properties of neat PLA, regardless of the percentage weight added.
SCIENTIFIC REPORTS
(2022)
Article
Polymer Science
Camila Beatriz de Souza Medeiros, Bruna Louise Silva, Antonio Marcos Medeiros, Jose Daniel Diniz Melo, Ana Paula Cysne Barbosa
Summary: This study evaluated the changes in properties of 3D-printed PLA material when immersed in a simulated biological media, for potential applications in implantable devices. The results showed that immersion caused an initial increase and subsequent decrease in mass, as well as chemical alterations and an increase in glass transition temperature. Although there were no significant changes in flexural strength, the fatigue life of the immersed samples decreased by an average of 57% to 77%.
Review
Polymer Science
Xiangrui Li, Yu Lin, Mingli Liu, Lipeng Meng, Chunfeng Li
Summary: This article focuses on the synthesis, modification, degradation, and application of polylactic acid (PLA), emphasizing the use of environmentally friendly materials for PLA modification and the applications of PLA composites in various fields such as construction, medical, packaging, and oil and water separation.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Polymer Science
Preeyaporn Injorhor, Tatiya Trongsatitkul, Jatuporn Wittayakun, Chaiwat Ruksakulpiwat, Yupaporn Ruksakulpiwat
Summary: Biodegradable polymers have important applications in medicine, particularly in internal devices, due to their ability to be broken down and absorbed into the body without producing harmful degradation products. In this study, biodegradable polylactic acid (PLA)-polyhydroxyalkanoate (PHA)-based nanocomposites with various PHA and nano-hydroxyapatite (nHAp) contents were prepared using solution casting method. The mechanical properties, microstructure, thermal stability, thermal properties, and in vitro degradation of the PLA-PHA-based composites were investigated. PLA-20PHA/5nHAp showed the desired properties and was successfully fabricated into fibers using electrospinning.
Article
Engineering, Environmental
Jinxuan Chen, Zhishuo Liu, Shuang Qiu, Yuchun Li, Jun Sun, Hongfei Li, Xiaoyu Gu, Sheng Zhang
Summary: In this study, a bio-based additive (PA-Fe-HBT) with core-shell structure is synthesized to improve the using performance and recycling performance of polylactic acid (PLA). The presence of 3 wt% PA-Fe-HBT increases the limited oxygen index to 25.5% and allows the sample to pass UL-94 V-0 grade. The mechanical properties of the composites remain good, and the ultraviolet aging resistance and ultraviolet protection ability are significantly improved. Furthermore, PA-Fe-HBT promotes the chemical recycling of the composites without external heating, resulting in 88% purity of lactic acid after simple purification.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Patryk Fryn, Sebastian Lalik, Krzysztof A. Bogdanowicz, Natalia Gorska, Agnieszka Iwan, Monika Marzec
Summary: The aim of this study was to investigate the influence of environmental pH on the degradation of a ternary composite layer. The results showed that the degradation process of both the neat polymer and composite layers was poor under standard air conditions, distilled water, and 0.1 M HCl solution. However, erosion of the surface layer stored in 0.1 M NaOH solution was observed after 6 days. The longer storage in 0.1 M NaOH solution resulted in complete degradation of the polymer layer, while the composite layer survived for up to 62 days. Admixtures of 5CB and SWCN were found to accelerate the degradation of the polymer in the composite layer and act as plasticizers.
Article
Chemistry, Physical
Juliana da Silva Favero, Jonathan Parisotto-Peterle, Valeria Weiss-Angeli, Rosmary Nichele Brandalise, Lucas Bonan Gomes, Carlos Perez Bergmann, Venina dos Santos
APPLIED CLAY SCIENCE
(2016)
Article
Materials Science, Multidisciplinary
Marielen Longhi, Rosiana Boniatti Casagrande, Sandra Raquel Kunst, Venina dos Santos, Jane Zoppas Ferreira
MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS
(2019)
Article
Materials Science, Biomaterials
Michele Savaris, Charlene Silvestrin Celi Garcia, Mariana Roesch-Ely, Joao Antonio Pegas Henriques, Venina dos Santos, Rosmary N. Brandalise
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2019)
Article
Chemistry, Physical
Juliana da Silva Favero, Venina dos Santos, Valeria Weiss-Angeli, Lucas Bonan Gomes, Diego Gusmao Veras, Norberto Dani, Andre Sampaio Mexias, Carlos Perez Bergmann
APPLIED CLAY SCIENCE
(2019)
Article
Materials Science, Multidisciplinary
Julia Daneluz, Juliana da Silva Favero, Venina dos Santos, Valeria Weiss-Angeli, Lucas Bonan Gomes, Andre Sampaio Mexias, Carlos Perez Bergmann
MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS
(2020)
Article
Materials Science, Multidisciplinary
Dionisio da Silva Biron, Venina dos Santos, Carlos Perez Bergmann
MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS
(2020)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
