Article
Materials Science, Coatings & Films
Joel da Silva Rodrigues, Leonardo Marasca Antonini, Antonio Alexandre da Cunha Bastos, Jie Zhou, Celia de Fraga Malfatti
Summary: The study applied plasma electrolytic oxidation (PEO) to create a coating on a magnesium alloy, ZK30, enhancing its corrosion resistance and wear resistance for potential orthopedic applications involving friction and wear. This technology has shown promising results in reducing hydrogen release, decreasing susceptibility to localized corrosion, and altering surface topography and chemistry.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Chemistry, Physical
Y. Zhang, J. Y. Dai, L. Zhao, L. P. Wu
Summary: In this study, a KMgF3 film coated AZ31 magnesium alloy was successfully prepared, which exhibited improved corrosion resistance and biocompatibility. Surface morphology observations and performance testing results showed that the KMgF3 film coated alloy had a 68% reduction in hydrogen evolution and an approximately 49 times higher corrosion current density compared to the uncoated alloy. Additionally, the KMgF3 film demonstrated better durability in simulated body fluid and enhanced the proliferation of bone marrow mesenchymal stem cells.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Chemistry, Physical
Jithu Jayaraj, A. Srinivasan, C. Arunchandran, V. Rajinikanth
Summary: This study proposes a two-stage chemical conversion coating process for magnesium alloys. The results show that the water-based coating has self-healing characteristics, while the ethanol-based coating has better corrosion resistance. Both coatings exhibit acceptable cell viability under physiological conditions.
APPLIED SURFACE SCIENCE
(2024)
Article
Biotechnology & Applied Microbiology
Gen Li, Yin Zhang, Jiezhou Wu, Renhao Yang, Qi Sun, Yidong Xu, Bo Wang, Ming Cai, Yang Xu, Chengyu Zhuang, Lei Wang
Summary: This study explores the effects and mechanism of adipose stem cells-derived exosomes (ADSCs-Exos) and ADSCs-Exos modified tissue engineering scaffold on bone defect repair. The results demonstrate that ADSCs-Exos promote the proliferation, migration, and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs), and ADSCs-Exos modified scaffold enhances the repair of BMSCs and bone defects both in vitro and in vivo.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Materials Science, Ceramics
Mostafizur Rahman, Mohammad Asaduzzaman Chowdhury, Md Shahin Mia, Md Ramjan Ali, Atiqur Rahman, Md Osman Ali, Saifullah Mahmud
Summary: This study reported a novel interfacial engineering approach for the fabrication of polymer/ceramic hybrid coating on magnesium alloy, which significantly improved mechanical properties, enhanced biointerface property, and slowed down degradation in simulated body fluid. The hybrid coating also improved corrosion resistance and enhanced biocompatibility and bioactivity.
CERAMICS INTERNATIONAL
(2022)
Article
Metallurgy & Metallurgical Engineering
Zeeshan Ur Rahman, Maqsood Ali, Ye-Tang Pan, David G. Churchill, Bon Heun Koo
Summary: In this study, the addition of (EDTA)4- in alkaline silicates electrolyte was found to result in thick and layered pancake-like materials with minimum cracks and porosity. The analysis also revealed that EDTA can significantly alter the surface layers composition and act as a passivation agent. However, no individual polycrystalline phases were formed. The corrosion potential of the coated AZ91 was positive, but the results were not consistent with the cyclic polarization tests.
JOURNAL OF MAGNESIUM AND ALLOYS
(2023)
Article
Engineering, Biomedical
Julia Gao, Yingchao Su, Yi-Xian Qin
Summary: This study compared the in vitro and in vivo degradation and biocompatibility behaviors of magnesium alloys with calcium phosphate coatings, showing that the CaP coating significantly improved biodegradation behavior and biocompatibility of the Mg alloy. In vitro tests were found to be a quick screening tool for biodegradation rate, with the in vivo degradation rate being slower than in vitro immersion degradation rate.
BIOACTIVE MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Pablo Pou-Alvarez, Antonio Riveiro, Xose Ramon Novoa, Xueze Jin, Jesus del Val, Rafael Comesana, Mohamed Boutinguiza, Fernando Lusquinos, Julian R. Jones, Maria Teresa Perez-Prado, Juan Pou
Summary: The article introduces a new concept of locally controlling and guiding corrosion through laser surface treatment. Wet tests on AZ31 magnesium alloy samples show a 15-fold reduction in degradation rates with the treatment. Controlling the treatment conditions can restrict degradation to specific regions and drive it towards specific directions.
Article
Materials Science, Multidisciplinary
Saumyadeep Jana, Matt Olszta, Danny Edwards, Mark Engelhard, Avik Samanta, Hongtao Ding, Pratik Murkute, O. Burkan Isgor, Aashish Rohatgi
Summary: Laser surface processing improved the corrosion resistance of AZ31 alloy by forming a mixed metal oxide surface film and refining the size and number density of intermetallic particles.
Article
Biochemistry & Molecular Biology
Maria Yoshida, Ayumu Nakashima, Naoki Ishiuchi, Kisho Miyasako, Keisuke Morimoto, Yoshiki Tanaka, Kensuke Sasaki, Satoshi Maeda, Takao Masaki
Summary: Both adipose-derived and bone marrow-derived mesenchymal stem cells (ADSCs and BMSCs) can suppress renal fibrosis, with ADSCs showing a stronger effect under serum-containing culture conditions. However, ADSC infusion in mice may lead to a higher death rate from pulmonary embolism. Therefore, the selection of ADSCs or BMSCs for clinical applications should consider the target disease and culture method.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Victor J. Costela-Ruiz, Lucia Melguizo-Rodriguez, Chiara Bellotti, Rebeca Illescas-Montes, Deborah Stanco, Carla Renata Arciola, Enrico Lucarelli
Summary: The success of regenerative medicine depends on the appropriate selection of mesenchymal stem cell (MSC) sources, as they influence the regenerative milieu. MSCs from bone marrow, adipose tissue, and dental tissue are all potential candidates for oral and dental regeneration.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Si-Han Wang, Shiao-Pieng Lee, Chung-Wei Yang, Chun-Min Lo
Summary: Magnesium alloys with coatings show potential for bone substitute alternatives, but surface modification remains a challenge. The structure and Mg2+ concentration of FHA-Mg scaffolds significantly influence cell behavior, with cells on the scaffolds demonstrating better proliferation and osteogenic differentiation compared to those on culture dishes.
Article
Engineering, Biomedical
Meng Li, Jing Wu, Wenbo Geng, Yulu Yang, Xuan Li, Kun Xu, Ke Li, Yan Li, Qiaojian Duan, Pengfei Gao, Kaiyong Cai
Summary: Localized corrosion of 316L stainless steel reduces the viability, adhesion, proliferation, and osteogenic differentiation abilities of BMSCs. It causes cytotoxicity through the release of metallic ions and generates reactive oxygen species (ROS) around the corrosion pits, leading to oxidative stress and cell membrane depolarization. This study provides insights into corrosion-mediated degradation of cell function and material-cell interactions.
Article
Biotechnology & Applied Microbiology
Cheng-Chieh Wang, Jing-Ya Hung, Jun-Yen Uan, Chih-Yuan Fang, Yu-Lin Kuo, Wei-Jen Chang, Yoichi Ohiro, Ying-Sui Sun
Summary: The market for orthopedic implant alloys has grown significantly, leading to extensive research on biodegradable magnesium-based alloys for green medicine. This study immersed a Mg-9Li alloy in cell culture medium to simulate degradation and monitor its effects on cells. The presence of hydroxyl groups led to cell death, while a coating of MgCO3 (H2O)(3), HA, and α-TCP appeared on the sample surfaces, providing anti-corrosion effects and a conducive surface environment for osteoblast adhesion. This bio-simulation immersion analysis has important implications for the clinical use of Mg alloys in securing regenerated periodontal tissue.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Metallurgy & Metallurgical Engineering
A. S. Gnedenkov, S. L. Sinebryukhov, V. S. Filonina, V. S. Egorkin, A. Yu Ustinov, V. Sergienko, S. Gnedenkov
Summary: The electrochemical behavior of biodegradable magnesium alloy Mg-0.8Ca was evaluated using traditional and local scanning electrochemical methods. The corrosion rates and degradation process of the alloy were determined and the mechanism of bioresorption was proposed. The influence of alloy composition and microstructure on corrosion behavior and the composition of corrosion products were investigated. The study also highlighted the low applicability of uncoated Mg-0.8Ca alloy in implant surgery.
JOURNAL OF MAGNESIUM AND ALLOYS
(2022)
Article
Endocrinology & Metabolism
Abolfazl Mehdizadehkashi, Samaneh Rokhgireh, Kobra Tahermanesh, Neda Eslahi, Sara Minaeian, Mansooreh Samimi
Summary: The study suggests that vitamin D supplementation in patients with endometriosis can significantly reduce pelvic pain, decrease total-/HDL-cholesterol ratio, lower hs-CRP levels, and increase TAC levels.
GYNECOLOGICAL ENDOCRINOLOGY
(2021)
Review
Cell & Tissue Engineering
Ebrahim Rahmani-Moghadam, Vahideh Zarrin, Amir Mahmoodzadeh, Marzieh Owrang, Tahereh Talaei-Khozani
Summary: Breast milk contains a diverse population of cells, including mesenchymal stem cells (MSC). These breast milk-derived stem cells share common markers with stem cells from other sources and have the potential to differentiate into various cell lineages. The ability of breast milk-derived stem cells to differentiate into neural stem cells, neurons, adipocytes, hepatocytes, chondrocytes, osteocytes, and cardiomyocytes make them a promising source of stem cells in regenerative medicine.
CURRENT STEM CELL RESEARCH & THERAPY
(2022)
Article
Obstetrics & Gynecology
Kobra Tahermanesh, Soheil Hanjani, Roya Shahriyari, Abbas Fazel Anvari-Yazdi, Leila Allahqoli, Ibrahim Alkatout
Summary: Modern surgical technologies allow gynecologists to treat most submucosal myomas hysteroscopically by some form of resection. The effect of the distending media used during myoma resection can vary depending on the morphology of the myomas. The blooming phenomenon can affect the panoramic view and treatment outcomes of myomas.
JOURNAL OF THE TURKISH-GERMAN GYNECOLOGICAL ASSOCIATION
(2022)
Article
Cell Biology
Mona Latifi, Mahsa Sani, Mahin Salmannejad, Maryam Kabir-Salmani, Hanieh Babakhanzadeh Bavanati, Tahereh Talaei-Khozani
Summary: The 3D porous hydroxyapatite (HA) reinforced by zirconia (ZrO2) coating and treated with a combination of platelet rich plasma (PRP) and Heparin sulfate (HS) showed synergistic effects on the adipose mesenchymal stem cells (ADMSCs) even without chemical induction. The scaffold provided a higher osteoconductive microenvironment for stem cell differentiation into osteoblasts.
CELL AND TISSUE BANKING
(2022)
Editorial Material
Obstetrics & Gynecology
Kobra Tahermanesh, Soheil Hanjani, Seyed Reza Saadat Mostafavi, Roya Shahriyari, Abbas Fazel Anvari-Yazdi, Mojgan Karimi-Zarchi, Mansooreh Samimi, Anita Karimi, Leila Allahqoli, Ibrahim Alkatout
Summary: This study presents a case of uterine ‘hourglass’ cesarean scar, characterized by the presence of an ‘external niche’ in conjunction with the internal niche at the lower uterine segment, resulting from inadequate uterine wound healing.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Article
Cell & Tissue Engineering
Atefeh Yaghoubi, Negar Azarpira, Saied Karbalay-Doust, Sajad Daneshi, Zahra Vojdani, Tahereh Talaei-Khozani
Summary: This study investigated the use of BM-MSC and prednisolone to reduce fibrosis and balance inflammatory cell migration. The results showed that loading prednisolone into the scaffold can effectively restrict inflammation, and the cell/prednisolone-loaded bioscaffold plays an important role in regeneration and angiogenesis.
STEM CELL RESEARCH & THERAPY
(2022)
Article
Orthopedics
Sara Sadat Nabavizadeh, Tahereh Talaei-Khozani, Moein Zarei, Shahrokh Zare, Omid Koohi Hosseinabadi, Nader Tanideh, Sajad Daneshi
Summary: The study evaluated the effects of SMMSCs, PRP, and secretome on collagenase II-induced rat knee osteoarthritis. Results showed that the combination of SMMSCs/secretome/PRP had a significant effect on glycosaminoglycans and collagen II contents, indicating better therapeutic efficacy.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2022)
Article
Obstetrics & Gynecology
Masoumeh Akmali, Roghayeh Yalmeh, Tahereh Talaei-Khozani, Fatemeh Karimi, Elham Aliabadi
Summary: This study evaluated the effects of kisspeptin on mouse testicular sperm. The results showed that kisspeptin can improve sperm motility and LDHC enzyme activity, but does not impact the frequency of non-capacitated, intact, and acrosomal-reacted sperms.
INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE
(2022)
Article
Obstetrics & Gynecology
Kobra Tahermanesh, Mansoureh Gorginzadeh, Soheil Hanjani, Roya Shahriyari, Abbas Fazel Anvari-Yazdi, Hamidreza Kelarestaghi, Ibrahim Alkatout, Leila Allahqoli
Summary: This article describes a simple and inexpensive device to address the challenges in laparoscopic ovarian cystectomy. The device allows for lifting and stabilizing the ovary without damaging the ovarian tissue or ligaments, preventing repeated falling of the ovary and saving operative time.
JOURNAL OF THE TURKISH-GERMAN GYNECOLOGICAL ASSOCIATION
(2022)
Review
Immunology
Tahereh Talaei-Khozani, Atefeh Yaghoubi
Summary: Regenerative medicine and tissue engineering are reasonable techniques for repairing failed tissues and could be an alternative to organ transplantation. Decellularization procedure preserves important compositions of extracellular matrix and allows cell migration and angiogenesis. Studying events after transplantation is crucial for understanding the effects and mechanisms of these techniques.
TRANSPLANT IMMUNOLOGY
(2022)
Article
Education, Scientific Disciplines
Kobra Tahermanesh, Maryam Maleki, Farid Rezaei Moghaddam, Parisa Nejati, Roya Shahriyari, Abbas Fazel Anvari-Yazdi, Arnoush Rahnama Moghadam, Hamid Salehiniya, Peyman Falahatinodeh, Leila Allahqoli, Ibrahim Alkatout
Summary: This study aimed to evaluate the effects of corrective exercises on the quality of life and work-related musculoskeletal disorders in surgical residents. The results showed that corrective exercises significantly reduced the incidence of work-related musculoskeletal disorders and improved the quality of life for surgical residents.
JOURNAL OF SURGICAL EDUCATION
(2023)
Review
Engineering, Biomedical
X. B. Chen, A. Fazel Anvari-Yazdi, X. Duan, A. Zimmerling, R. Gharraei, N. K. Sharma, S. Sweilem, L. Ning
Summary: Bioinks combine biomaterials and living cells, and are used in extrusion bioprinting to create 3D structures that resemble human tissue or organs. These printed constructs have various applications in tissue engineering and in vitro tissue modeling. The properties of the bioinks, including rheological, mechanical, and biological properties, as well as the printing process, play a crucial role in successful printing and application. This article critically reviews the latest developments in bioinks and biomaterial solutions for extrusion bioprinting, emphasizing bioink synthesis, characterization, and their influence on the printing process.
BIOACTIVE MATERIALS
(2023)
Article
Cell Biology
Khatereh Fazelian-Dehkordi, Sayed Fakhroddin Mesbah Ardekani, Tahereh Talaei-Khozani
Summary: This study compared the efficiency of three protocols for decellularizing sheep greater omentum (GOM), and found that the protocol based on 1% SDS was more effective in preserving extracellular matrix (ECM) compared to the other protocols. This protocol can be considered a superior choice for tissue engineering applications.
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
