Article
Electrochemistry
Zainab Javeed, Muhammad Ibrahim, Muhammad Faisal Iqbal, Rahat Nawaz, Dilshad Hussain, Muhammad Ayub, Muhammad Naeem Ashiq, Saadat Majeed, Muahmmad Najam-ul-Haq, Batool Fatima
Summary: Early detection of xanthine levels in human blood is crucial for minimizing risks associated with metabolic disorders. A non-enzymatic xanthine sensor was fabricated using lanthanum sulfide nanoparticles, showing good conductivity, large surface area, fast electron transfer, and promising sensing capability for xanthine detection.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Prateek Sharma, Deeksha Thakur, Devendra Kumar
Summary: A rapid, reliable, and user-friendly electrochemical sensor was developed for the detection of xanthine (Xn), an important biomarker of food quality. The sensor was created using a single-pot hydrothermal method and comprised a nanocomposite of molybdenum disulfide-molybdenum trioxide (MoS2/MoO3). The nanocomposite demonstrated excellent stability, high surface-to-volume ratio, and biocompatibility, making it a promising approach for early detection devices for Xn.
Article
Electrochemistry
Amoolya Chandran, K. Girish Kumar
Summary: In addition to their physiological roles, hormones and purine metabolites are recognized biomarkers for disease detection and monitoring. This article discusses the development of a voltammetric sensor for the selective determination of EP, UA, XA, and HX. The sensor utilizes a copolymer modification that allows for well-defined peaks and a wide linear range with low detection limits.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2023)
Article
Food Science & Technology
Miaomiao Peng, Zhuosheng Chen, Qiuping Deng, Shijiang Zhu, Guang Wang
Summary: The study showed that peanut hull extract enriched in luteolin has a protective effect on erythrocytes against HX-XOD-induced damage by inhibiting reactive oxygen species generation and preserving antioxidative enzymes and non-enzymatic substances.
Article
Chemistry, Physical
Muthusankar Ganesan, Keerthika Devi Ramadhass, Ho-Chiao Chuang, Gopu Gopalakrishnan
Summary: Simultaneous quantification of anticancer drug 5-fluorouracil and inflammatory agents uric acid and xanthine was achieved through a novel electrochemical approach using nitrogen-doped carbon quantum dots decorated iron oxide in a ternary nanocomposite. The modified electrode exhibited excellent sensitivity, stability, repeatability, and reproducibility for the detection of these analytes, showing great potential for practical applications in biological fluids.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Analytical
Kubra Turan, Ahmet Uge, Bulent Zeybek, Gozde Aydogdu Tig
Summary: In this study, a poly(N-methyl aniline)-cerium oxide-functionalized MWCNTs composite was synthesized and used as a modifier for simultaneous detection of uric acid and 5-fluorouracil. The composite exhibited excellent sensing performance with a wide linear working range and low detection limits. The effect of interfering substances on the electrochemical response was investigated, confirming the stability and anti-interference ability of the sensing platform.
ANALYTICAL METHODS
(2023)
Article
Nanoscience & Nanotechnology
Zhenlong Jiang, Hui Dong, Yanli Zhou, Yanan Chen, Wanqing Hao, Ziyi Zhang, Yizhao Hao, Lantao Liu, Xiaobing Wang, Maotian Xu
Summary: A ratiometric electrochemical detection platform was constructed to simultaneously determine the levels of uric acid (UA) and xanthine (XA). The cPDA-Gp electrode was prepared by in situ modification of polydopamine (PDA) on graphene paper (Gp) and subsequent carbonization. Methylene blue (MB) was used as an internal reference and coupled with cPDA-Gp. The sensing platform showed promising results for the detection of UA and XA in real samples.
ACS APPLIED NANO MATERIALS
(2023)
Article
Electrochemistry
Zhengcai Guo, Guiyan Wang, Jinlian Li, Dongmei Wu, Xiaoling Guo
Summary: This paper describes a new strategy for trace determination of uric acid, xanthine, and hypoxanthine using a miniaturized electrochemical biosensor. The biosensor exhibited excellent electrocatalytic activity and good reproducability, making it suitable for practical sample analysis. The device is easily available, cost-effective, and simple to fabricate.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2021)
Article
Chemistry, Analytical
Sevilay Erdogan Kablan, Abdulkadir Yilmaz, Umit Kervan, Nuran Ozaltin, Emirhan Nemutlu
Summary: Cardiopulmonary bypass during cardiac surgery may cause a systemic inflammatory reaction, leading to complications such as acute renal failure. This study developed an electroanalytical method for simultaneous analysis of three biomarkers in plasma samples and successfully applied it to early diagnosis of ARF after CPB.
Article
Chemistry, Analytical
Mohammad Hossein Ghanbari, Zahra Norouzi, Bastian J. M. Etzold
Summary: In this study, a multinary nanocomposite was designed for the detection of theophylline (TP) and uric acid (UA) in blood serum, showing high sensitivity and selectivity. The multinary nanocomposite improved the electrochemically active surface area and electron transfer rate, leading to enhanced current response. The detection limits were found to be 0.18 nM for UA and 0.36 nM for TP, with sensitivities of 1.27 μA μM-1 cm-2 and 1.06 μA μM-1 cm-2, respectively.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Di Zhu, Xinying Li, Lili Fu, Tianshuo Bai, Qin Wang, Chunlei Ma, Xin Sun, Lixin Lin, Xuemei Li
Summary: A cost-effective and environmentally friendly method has been proposed for synthesizing a nanomaterial composed of highly dispersed cerium oxide nanoparticles anchored on sulfur-doped scaly carbon. This nanomaterial was utilized for the modification of a glassy carbon electrode to create an electrochemical sensor capable of detecting uric acid. The sensor exhibited a wide linear concentration range, low detection limit, and exceptional levels of selectivity, stability, reproducibility, and repeatability.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Analytical
Ayca Urcuk, Ceren Yildiz, Dilek Eskikoy Bayraktepe, Zehra Yazan
Summary: A pencil graphite electrode coated with halloysite nanotubes and magnetite nanoparticles was used for simultaneous quantitative analysis of caffeic acid and uric acid in biological samples. The sensor showed an increased effective surface area and improved oxidation peak currents for both analytes compared to a bare electrode.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Di Zhu, Jianjiao Xin, Xuemei Li
Summary: A self-assembly strategy is used to synthesize vanadium tetrasulfide nanospheres embedded into nitrogen-doped biomass-derived porous carbon materials. The resulting VS4@N-BPC exhibits hierarchical connectivity and a unique porous structure, leading to excellent electrochemical performance and sensing activity.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Analytical
S. Meenakshi, S. Anitta, A. Sivakumar, S. A. Martin Britto Dhas, C. Sekar
Summary: A novel electrochemical sensor based on shock wave treated Iron (III) oxide nanoparticles was reported for simultaneous detection of Riboflavin, Uric acid, and Folic acid. The sensor showed low detection limits within different concentration ranges and maintained good response in the presence of interfering substances.
MICROCHEMICAL JOURNAL
(2021)
Article
Engineering, Electrical & Electronic
Wenzheng He, Xiongying Ye, Tianhong Cui
Summary: This paper introduces a method to improve the selectivity of electrochemical sensors by introducing a heterogeneous electrode interface and modifying graphene and gold nanoparticles on a flexible substrate. The sensor shows low detection limits and is suitable for detecting dopamine and uric acid at the lowest concentration in the human body.
IEEE SENSORS JOURNAL
(2021)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)