Comparison of originator and biosimilar therapeutic monoclonal antibodies using comprehensive two-dimensional liquid chromatography coupled with time-of-flight mass spectrometry

Characterization of cetuximab Fc/2 dimers by off-line CZE-MS

(2016) Yannis-Nicolas François et al.   ANALYTICA CHIMICA ACTA

Independent highly sensitive characterization of asparagine deamidation and aspartic acid isomerization by sheathless CZE-ESI-MS/MS

(2016) Rabah Gahoual et al.   JOURNAL OF MASS SPECTROMETRY

Glycoform Separation and Characterization of Cetuximab Variants by Middle-up Off-Line Capillary Zone Electrophoresis-UV/Electrospray Ionization-MS

(2015) Michael Biacchi et al.   ANALYTICAL CHEMISTRY

Integrated Microfluidic Capillary Electrophoresis-Electrospray Ionization Devices with Online MS Detection for the Separation and Characterization of Intact Monoclonal Antibody Variants

(2015) Erin A. Redman et al.   ANALYTICAL CHEMISTRY

Direct Identification of Rituximab Main Isoforms and Subunit Analysis by Online Selective Comprehensive Two-Dimensional Liquid Chromatography–Mass Spectrometry

(2015) Dwight R. Stoll et al.   ANALYTICAL CHEMISTRY

Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies

(2015) Alain Beck et al.   JOURNAL OF MASS SPECTROMETRY

Regulatory considerations in oncologic biosimilar drug development

(2015) Judith C Macdonald et al.   mAbs

Monoclonal antibody biosimilars

(2015) Natasha Udpa et al.   NATURE REVIEWS DRUG DISCOVERY

Comprehensive two-dimensional liquid chromatography of therapeutic monoclonal antibody digests

(2014) Gerd Vanhoenacker et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Rapid comparison of a candidate biosimilar to an innovator monoclonal antibody with advanced liquid chromatography and mass spectrometry technologies

(2014) Hongwei Xie et al.   mAbs

Physicochemical characterization of Remsima®

(2014) Soon Kwan Jung et al.   mAbs

Monoclonal antibodies biosimilarity assessment using transient isotachophoresis capillary zone electrophoresis-tandem mass spectrometry

(2014) Rabah Gahoual et al.   mAbs

Approval of the first biosimilar antibodies in Europe

(2013) Alain Beck et al.   mAbs

Analytical characterization of biosimilar antibodies and Fc-fusion proteins

(2013) Alain Beck et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

A Platform for Characterizing Therapeutic Monoclonal Antibody Breakdown Products by 2D Chromatography and Top-Down Mass Spectrometry

(2012) Matthew T. Mazur et al.   AAPS Journal

Biosimilar, Biobetter, and Next Generation Antibody Characterization by Mass Spectrometry

(2012) Alain Beck et al.   ANALYTICAL CHEMISTRY

On-line coupling of size exclusion chromatography with mixed-mode liquid chromatography for comprehensive profiling of biopharmaceutical drug product

(2012) Yan He et al.   JOURNAL OF CHROMATOGRAPHY A

Multidimensional gas chromatography

(2012) Philip J. Marriott et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

On-line characterization of monoclonal antibody variants by liquid chromatography–mass spectrometry operating in a two-dimensional format

(2011) Melissa Alvarez et al.   ANALYTICAL BIOCHEMISTRY

Biosimilars of Biological Drug Therapies

(2011) George Dranitsaris et al.   DRUGS

Biosimilar agents in oncology/haematology: from approval to practice

(2010) Dietger Niederwieser et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody

(2009) Josef Vlasak et al.   ANALYTICAL BIOCHEMISTRY

IgG glycosylation analysis

(2009) Carolin Huhn et al.   PROTEOMICS