Hepatic MCPIP1 protein levels are reduced in NAFLD patients and are predominantly expressed in cholangiocytes and liver endothelium

Deletion of Mcpip1 in Mcpip1fl/flAlbCre mice recapitulates the phenotype of human primary biliary cholangitis

(2021) Jerzy Kotlinowski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation

(2021) Ewelina Dobosz et al.   Disease Models & Mechanisms

A single cell gene expression atlas of 28 human livers

(2021) Joseph Brancale et al.   JOURNAL OF HEPATOLOGY

Role of Mcpip1 in obesity‐induced hepatic steatosis as determined by myeloid and liver‐specific conditional knockouts

(2021) Natalia Pydyn et al.   FEBS Journal

Peripheral immune cells in NAFLD patients: A spyhole to disease progression

(2021) Shuang-Zhe Lin et al.   EBioMedicine

New therapeutic strategies in nonalcoholic fatty liver disease: a focus on promising drugs for nonalcoholic steatohepatitis

(2020) Natalia Pydyn et al.   Pharmacological Reports

Characterization of the immune cell landscape of patients with NAFLD

(2020) Tom Diedrich et al.   PLoS One

Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity

(2020) Marion Régnier et al.   Scientific Reports

MCPIP1 RNase and Its Multifaceted Role

(2020) Richard Musson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Noninvasive diagnostic criteria for nonalcoholic steatohepatitis based on gene expression levels in peripheral blood mononuclear cells

(2019) Akira Kado et al.   JOURNAL OF GASTROENTEROLOGY

Integrative genomics reveal a role for MCPIP1 in adipogenesis and adipocyte metabolism

(2019) Magdalena Losko et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ectopic overexpression of MCPIP1 impairs adipogenesis by modulating microRNAs

(2018) Magdalena Losko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Monocyte chemoattractant protein-induced protein 1 targets hypoxia-inducible factor 1α to protect against hepatic ischemia/reperfusion injury

(2018) Peng Sun et al.   HEPATOLOGY

Modeling NAFLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016–2030

(2018) Chris Estes et al.   JOURNAL OF HEPATOLOGY

MCPIP1, alias Regnase-1 binds and cleaves mRNA of C/EBPβ

(2017) Barbara Lipert et al.   PLoS One

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

(2016) Alexandra Montagner et al.   GUT

MCPIP-1, Alias Regnase-1, Controls Epithelial Inflammation by Posttranscriptional Regulation of IL-8 Production

(2016) Ewelina Dobosz et al.   Journal of Innate Immunity

Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms

(2015) Takashi Mino et al.   CELL

Fibrosis Progression in Nonalcoholic Fatty Liver vs Nonalcoholic Steatohepatitis: A Systematic Review and Meta-analysis of Paired-Biopsy Studies

(2015) Siddharth Singh et al.   Clinical Gastroenterology and Hepatology

PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis

(2015) Sven Francque et al.   JOURNAL OF HEPATOLOGY

Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease

(2015) Michal Pawlak et al.   JOURNAL OF HEPATOLOGY

Monocyte chemoattractant protein-induced protein 1 impairs adipogenesis in 3T3-L1 cells

(2014) Barbara Lipert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Antidicer RNAse activity of monocyte chemotactic protein-induced protein-1 is critical for inducing angiogenesis

(2013) Arpita Roy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

MCPIP1 Deficiency in Mice Results in Severe Anemia Related to Autoimmune Mechanisms

(2013) Zhou Zhou et al.   PLoS One

MCPIP1 Ribonuclease Antagonizes Dicer and Terminates MicroRNA Biogenesis through Precursor MicroRNA Degradation

(2011) Hiroshi I. Suzuki et al.   MOLECULAR CELL

Osteoclast precursor differentiation by MCPIP via oxidative stress, endoplasmic reticulum stress, and autophagy

(2011) Kangkai Wang et al.   Journal of Molecular Cell Biology

MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-κB signaling

(2010) Jian Liang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peripheral Blood Mononuclear Cells as a Model to Study the Response of Energy Homeostasis-Related Genes to Acute Changes in Feeding Conditions

(2010) Antoni Caimari et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1β mRNA

(2009) Danuta Mizgalska et al.   FEBS Journal

Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

(2009) Kazufumi Matsushita et al.   NATURE

A pilot trial of fenofibrate for the treatment of non-alcoholic fatty liver disease

(2008) C. Fernández-Miranda et al.   DIGESTIVE AND LIVER DISEASE

Differential Expression of Oxidative Stress and Inflammation Related Genes in Peripheral Blood Mononuclear Cells in Response to a Low-Calorie Diet: A Nutrigenomics Study

(2008) Ana B. Crujeiras et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY