Chemical Activation and Mechanical Sensitization of Piezo1 Enhance TRAIL-Mediated Apoptosis in Glioblastoma Cells

Fluid shear stress enhances T cell activation through Piezo1

(2022) Jacob M. Hope et al.   BMC BIOLOGY

Integrative analysis of therapy resistance and transcriptomic profiling data in glioblastoma cells identifies sensitization vulnerabilities for combined modality radiochemotherapy

(2022) Leon Emanuel Schnöller et al.   Radiation Oncology

The DNA Double-Strand Break Repair in Glioma: Molecular Players and Therapeutic Strategies

(2022) Semer Maksoud   MOLECULAR NEUROBIOLOGY

Effect of tetrahydroquinoline derivatives on the intracellular Ca2+ homeostasis in breast cancer cells (MCF-7) and its relationship with apoptosis.

(2022) Semer Maksoud et al.   INVESTIGACION CLINICA

Taxanes Sensitize Prostate Cancer Cells to TRAIL-Induced Apoptotic Synergy via Endoplasmic Reticulum Stress

(2021) Korie A. Grayson et al.   MOLECULAR CANCER THERAPEUTICS

Overcoming TRAIL-resistance by sensitizing prostate cancer 3D spheroids with taxanes

(2021) Korie A. Grayson et al.   PLoS One

In Vitro and In Vivo Enhancement of Temozolomide Effect in Human Glioblastoma by Non-Invasive Application of Cold Atmospheric Plasma

(2021) Vikas Soni et al.   Cancers

Channeling the Force: Piezo1 Mechanotransduction in Cancer Metastasis

(2021) Jenna A. Dombroski et al.   Cells

ER-Mitochondria Calcium Flux by β-Sitosterol Promotes Cell Death in Ovarian Cancer

(2021) Hyocheol Bae et al.   Antioxidants

Temozolomide: An Updated Overview of Resistance Mechanisms, Nanotechnology Advances and Clinical Applications

(2020) Raúl Ortiz et al.   Current Neuropharmacology

Hypo-fractionated FLASH-RT as an effective treatment against glioblastoma that reduces neurocognitive side effects in mice

(2020) Pierre Montay-Gruel et al.   CLINICAL CANCER RESEARCH

Activation of Piezo1 sensitizes cells to TRAIL-mediated apoptosis through mitochondrial outer membrane permeability

(2019) Jacob M. Hope et al.   Cell Death & Disease

A mechanism for the activation of the mechanosensitive Piezo1 channel by the small molecule Yoda1

(2019) Wesley M. Botello-Smith et al.   Nature Communications

Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1

(2018) Jerome J. Lacroix et al.   Nature Communications

Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism

(2018) Frank A. Lincoln et al.   Cell Death & Disease

Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients

(2016) Christine Jungk et al.   BMC CANCER

TRAIL-coated leukocytes that prevent the bloodborne metastasis of prostate cancer

(2016) Elizabeth C. Wayne et al.   JOURNAL OF CONTROLLED RELEASE

Calcium Sensitive Fluorescent Dyes Fluo-4 and Fura Red under Pressure: Behaviour of Fluorescence and Buffer Properties under Hydrostatic Pressures up to 200 MPa

(2016) D. Schneidereit et al.   PLoS One

Piperlongumine and immune cytokine TRAIL synergize to promote tumor death

(2015) Jiahe Li et al.   Scientific Reports

Chemical activation of the mechanotransduction channel Piezo1

(2015) Ruhma Syeda et al.   eLife

Gingerol sensitizes TRAIL-induced apoptotic cell death of glioblastoma cells

(2014) Dae-Hee Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Fluid shear stress sensitizes cancer cells to receptor-mediated apoptosis via trimeric death receptors

(2013) Michael J Mitchell et al.   NEW JOURNAL OF PHYSICS

Inducing Apoptosis in Rolling Cancer Cells: A Combined Therapy with Aspirin and Immobilized TRAIL and E-Selectin

(2012) Kuldeepsinh Rana et al.   MOLECULAR PHARMACEUTICS

Glioblastoma stem cells

(2011) Ghazaleh Tabatabai et al.   CELL AND TISSUE RESEARCH

Secretome Signature of Invasive Glioblastoma Multiforme

(2011) Catherine A. Formolo et al.   JOURNAL OF PROTEOME RESEARCH

Ratiometric high-resolution imaging of JC-1 fluorescence reveals the subcellular heterogeneity of astrocytic mitochondria

(2011) Vera C. Keil et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Modified Annexin V/Propidium Iodide Apoptosis Assay For Accurate Assessment of Cell Death

(2011) Aja M. Rieger et al.   Jove-Journal of Visualized Experiments

Expression, purification and use of recombinant annexin V for the detection of apoptotic cells

(2009) Susan E Logue et al.   Nature Protocols