Vitamin D, Cholesterol, and DXA Value Relationship with Bimaxillary Cone Beam CT Values

We evaluated the correlation that Vitamin D (Vit D), cholesterol levels, and T- and Z-scores of dual-energy X-ray absorptiometry (DXA) scans have with cone beam computed tomography values assessed in the anterior and posterior regions of maxillary and mandibular jaws. In total, 187 patients were recruited for this clinical study. Patients' ages ranged between 45 and 65 years. Patients with valid DXA results, serum Vit D and cholesterol levels, and no evidence of bone disorders in the maxilla or mandibular region were included in the study and grouped in the control (non-osteoporosis) and case (osteoporosis) groups. Patients with a history of medical or dental disease that might complicate the dental implant therapy, chronic alcohol users, and patients who took calcium or Vit D supplements were excluded. The outcome variables assessed in the investigation were Vit D, cholesterol, Z-values, and cone beam computed tomography values. Regarding the case group, a significant (p < 0.05) inverse relationship was observed between Vit D and cholesterol. Although insignificant (p > 0.05), a positive relationship was found between Vit D and the cone beam computed tomography values in all regions of the jaws, except the mandibular posterior region (p < 0.05). Pearson correlation analysis was carried out. Vit D and cholesterol showed a statistically insignificant (p > 0.05) negative association with the cone beam computed tomography values in all regions of the jaws. However, the Z-values were highly correlated with the cone beam computed tomography values in all regions of the jaws (r > 7, p < 0.05). Vit D, cholesterol levels, and Z-values in women and men from young adulthood to middle age (45-65) were related with the cone beam computed tomography values of the jaws.

Automated summary

This clinical study evaluated the correlation between Vitamin D (Vit D), cholesterol levels, and T- and Z-scores of dual-energy X-ray absorptiometry (DXA) scans with cone beam computed tomography values in the maxillary and mandibular jaws. A total of 187 patients aged between 45 and 65 were included in the study, divided into control (non-osteoporosis) and case (osteoporosis) groups. The results showed a significant inverse relationship between Vit D and cholesterol in the case group, and a positive relationship between Vit D and cone beam computed tomography values in all regions of the jaws except the mandibular posterior region. Pearson correlation analysis revealed an insignificant negative association between Vit D, cholesterol levels, and cone beam computed tomography values in all regions of the jaws, while Z-values were highly correlated with the cone beam computed tomography values in all regions of the jaws. Vit D, cholesterol levels, and Z-values were found to be related to the cone beam computed tomography values of the jaws in women and men aged 45-65.