Review
Polymer Science
Yutian Wu, Min Zeng, Quanyong Cheng, Caili Huang
Summary: Emulsion, as a fine dispersion of immiscible liquids, has widespread applications in various fields such as sustainable industry, biomedical reactions, and drug delivery. Stimuli-responsive emulsions that can demulsify on demand or change their properties are in high demand due to their noninvasive and environmentally friendly characteristics. Considerable progress has been made in developing physical stimuli-responsive emulsions, with valuable practical applications including controllable release cargo, oil recovery, and product separation.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Zhe Xiang, Xi Zhao, Guoxiang Wang, Chenze Qi, Sujing Zhou, Jinjing Li, Yong Gao
Summary: In this study, an efficient and recyclable platform for interfacial catalytic reaction was constructed using pH-responsive n-decane-in-water Pickering emulsions. The prepared emulsions showed high stability and rapid demulsification at low pH. The catalytic platform exhibited a far higher reaction efficiency compared to ordinary n-decane-water systems. This study demonstrates the potential application of Pickering emulsions in heterogeneous reactions.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2023)
Article
Polymer Science
Devendra Kumar, Bhanendra Sahu, Subrata Dolui, Swati Singh Rajput, Md. Mehboob Alam, Sanjib Banerjee
Summary: A facile method based on recyclable nanoscale zero-valent iron (nZVI)-mediated photoRDRP in ionic liquid led to the synthesis of narrow disperse poly(2-(dimethylamino)ethyl methacrylate) and poly(2-(dimethylamino)ethyl methacrylate)-block-poly(4-vinylphenylboronic acid) (PDMAEMA-b-PVPBA) diblock copolymers. The stimuli response of the PDMAEMA-b-PVPBA copolymer to changes in pH, temperature, and sugar concentration was evaluated. The recyclability of the nZVI catalyst and ionic liquid solvent was confirmed. The polymerization process can be controlled by simply turning the UV-A irradiation on or off, providing temporal control for spatiotemporal ON/OFF applications. DFT calculations were conducted to determine the geometry of the involved species.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Polymer Science
Malihe Pooresmaeil, Hassan Namazi, Roya Salehi
Summary: A new photoluminescent and biocompatible nanostructured polymer brush was designed for doxorubicin delivery and evaluated through various characterization techniques. The nanostructure demonstrated good stability, biodegradability, and biocompatibility in vitro, along with targeted drug delivery capability, showing promise for targeted breast cancer therapy.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Polymer Science
Aleksey D. Drozdov
Summary: This study investigates five potential candidates to replace PNIPAm in biomedical and biotechnological applications by studying their equilibrium swelling properties and comparing them with substituted acrylamide gels. The (co)polymers are divided into three groups based on the strength of hydrophobic interactions, showing different responses at and above the volume phase transition temperature.
Review
Engineering, Chemical
Xue-hui Ge, Liangji Mo, Anhe Yu, Chenzi Tian, Xiaoda Wang, Chen Yang, Ting Qiu
Summary: Researchers have made recent advances in responsive emulsions that can be controlled through external stimuli such as pH, light, magnetic fields, CO2/N-2, and dual responses. These responsive emulsions offer advantages such as simple manipulation, good reversibility, low cost, and potential applications in catalytic reactions, heavy oil recovery, polymer particle synthesis, and optical sensors.
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2022)
Review
Polymer Science
Shuo Zhou, Min Zeng, Yanlin Liu, Xiaofeng Sui, Jinying Yuan
Summary: With reversible deactivated radical polymerization techniques, polymerization-induced self-assembly (PISA) has become a convenient method for preparing block copolymer nanoparticles in situ with high concentrations. These nanoparticles have wide potential applications in nanomedicine, coatings, nanomanufacture, and Pickering emulsions. By introducing stimulus responsiveness into PISA nanoparticles, Pickering emulsions stabilized with these nanoparticles can exhibit smart behaviors, allowing reversible emulsification and demulsification. This review focuses on recent progress in Pickering emulsions stabilized by stimuli-responsive PISA nanoparticles, discussing factors affecting the stability during emulsification and demulsification, as well as exploring applications in antibacterial agents, diphase reaction platforms, and multi-emulsions. The future developments and applications of stimuli-responsive Pickering emulsions stabilized by PISA nanoparticles are also highlighted.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Polymer Science
Derrick E. Hastings, Jose C. Bozelli, Richard M. Epand, Harald D. H. Stover
Summary: The transition from self-coacervation to complex coacervation of a series of charge-balanced polyampholyte (PA) and polyelectrolyte (PE) pairs based on copolymers of methacrylic acid and N-(3-aminopropyl) methacrylamide hydrochloride was described, focusing on the effects of charge distribution on coacervate properties. The study found that higher molecular weight complex coacervates exhibited increased resistance to stimuli such as ionic strength and pH, compared to liquid self-coacervates and less hydrated coacervates formed from two PE homopolymers with complementary nonstoichiometric PAs.
Review
Chemistry, Multidisciplinary
Tiefan Huang, Zhixin Su, Kun Hou, Jianxian Zeng, Hu Zhou, Lin Zhang, Suzana P. Nunes
Summary: This review summarizes the important developments and achievements in stimuli-responsive membranes, including the commonly utilized stimuli and strategies to prepare them. It discusses the control of membrane pore structure and surface properties, as well as the smart applications for separations. The remaining challenges and future prospects in this field are also reviewed.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Food Science & Technology
Zeyue Ren, Xiaojing Li, Fanyi Ma, Yun Zhang, Weiping Hu, Md Zaved Hossain Khan, Xiuhua Liu
Summary: In this study, oil-in-water emulsions made of medium-chain triglycerides, mucilage from Dioscorea opposita, and food-grade polysaccharides were prepared and their stability was compared. The results showed that low concentrations of pectin and mucilage from Dioscorea opposita improved the stability of emulsions, suggesting that mucilage from Dioscorea opposita has potential as a natural emulsifier.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Polymer Science
Shuanhu Qi, Leonid Klushin, Alexander M. Skvortsov, Friederike Schmid
Summary: The study reconsiders a smart responsive brush design based on conformational transition in block copolymers, demonstrating robust features and a surprising universality in transition properties related to the adsorption state.
Article
Chemistry, Applied
Fu-Zhen Zhou, Xin-Hao Yu, Dong-Hui Luo, Xiao-Quan Yang, Shou-Wei Yin
Summary: Water-in-oil (W/O) emulsions stabilized by biocompatible and biodegradable gliadin/ethyl cellulose complex particles (GECPs) were developed and characterized. The stability of the emulsions could be adjusted by varying the gliadin-to-ethyl cellulose ratio of the GECPs. Confocal laser scanning microscopy and theoretical calculations confirmed the formation of multiple interfacial layers by the GECPs, providing physical barriers against coalescence and contributing to the long-term stability of the emulsions.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Applied
Chao Lin, Pengju Pan, Guorong Shan, Miao Du
Summary: Poly(ethylene glycol)-b-poly(epsilon-caprolactone) diblock copolymers (PEG-b-PCL) with predesigned hydrophilic/hydrophobic block length ratios were synthesized and self-assembled into micelles for emulsifying medium-chain triglycerides with an aqueous phase. The relationship between the wettability of the copolymer micelles and their emulsification properties was proved, and various Pickering emulsions, including double-W/O/W emulsions, were controllably prepared through one-step homogenization. The double microstructure of W/O/W Pickering emulsion was demonstrated to be highly stable during long-term storage.
Article
Polymer Science
Setuhn Jimaja, Spyridon Varlas, Jeffrey C. Foster, Daniel Taton, Andrew P. Dove, Rachel K. O'Reilly
Summary: We report the synthesis of redox- and pH-sensitive block copolymer micelles that contain chiral cores composed of helical poly(aryl isocyanide)s. The introduction of cross-links and stimulus-sensitive nanostructures are achieved through post-polymerisation modification with various diamines. The stimuli-responsiveness of the nanoparticles towards a reducing agent and pH is evaluated by following the change in size using dynamic light scattering.
Article
Polymer Science
Erigene Bakangura, David Fournier, Fanny Coumes, Patrice Woisel, Daniel Grande, Benjamin Le Droumaguet
Summary: Functional nanoporous polymeric materials were prepared from novel PS-b-PEO diblock copolymer precursors containing reversible boronate ester junction. The generation of oriented cylindrical nanopores was achieved by selective etching of PEO under mild acidic conditions.
Article
Chemistry, Analytical
Valerie Geertsen, Elodie Barruet, Frederic Gobeaux, Jean-Luc Lacour, Olivier Tache
ANALYTICAL CHEMISTRY
(2018)
Article
Chemistry, Multidisciplinary
Frederic Gobeaux, Frank Wien
Article
Materials Science, Multidisciplinary
Florian Aubrit, Fabienne Testard, Aurelie Paquirissamy, Frederic Gobeaux, Xuan Wang, Frederic Nallet, Philippe Fontaine, Virginie Ponsinet, Patrick Guenoun
JOURNAL OF MATERIALS CHEMISTRY C
(2018)
Article
Green & Sustainable Science & Technology
David Azria, Raluca Guermache, Sophie Raisin, Sebastien Blanquer, Frederic Gobeaux, Marie Morille, Emmanuel Belamie
JOURNAL OF RENEWABLE MATERIALS
(2018)
Article
Chemistry, Multidisciplinary
Pierre Picot, Yuanyuan Liao, Elodie Barruet, Frederic Gobeaux, Thibaud Coradin, Antoine Thill
Article
Pharmacology & Pharmacy
Marie Rouquette, Karine Ser-Le Roux, Melanie Polrot, Claudie Bourgaux, Jean-Philippe Michel, Fabienne Testard, Frederic Gobeaux, Sinda Lepetre-Mouelhi
JOURNAL OF DRUG TARGETING
(2019)
Article
Chemistry, Multidisciplinary
Tobias Lange, Thibault Charpentier, Frederic Gobeaux, Sophie Charton, Fabienne Testard, Antoine Thill
Article
Chemistry, Physical
Pierre Picot, Frederic Gobeaux, Thibaud Coradin, Antoine Thill
APPLIED CLAY SCIENCE
(2019)
Article
Pharmacology & Pharmacy
Amandine Gendron, Natalie Lan Linh Tran, Julie Laloy, Romain Brusini, Aurelie Rachet, Frederic Gobeaux, Valerie Nicolas, Pierre Chaminade, Sonia Abreu, Didier Desmaele, Mariana Varna
Summary: Cyclosporin A (CsA) is an immunosuppressive molecule evaluated for ischemic heart diseases. A novel nanoformulation, SqCsA NPs, based on squalene and CsA has shown promising cardioprotective effects on cardiac cell lines, paving the way for potential medical applications.
Article
Biophysics
Avigail Baruch-Leshem, Corinne Chevallard, Frederic Gobeaux, Patrick Guenoun, Jean Daillant, Philippe Fontaine, Michel Goldmann, Ariel Kushmaro, Hanna Rapaport
Summary: The order of the catalytic triad residues along amphiphilic beta-strands affects both assembly structures and catalytic activity. The amphiphilic peptide ESH achieved the highest catalytic efficiency at a concentration of 250 μM.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Pharmacology & Pharmacy
Marie Caillaud, Frederic Gobeaux, Miryana Hemadi, Suzan Boutary, Patrick Guenoun, Didier Desmaele, Patrick Couvreur, Frank Wien, Fabienne Testard, Liliane Massaad-Massade
Summary: siRNA-SQ nanoparticles have stability and the ability to interact with serum components, making them a promising targeted therapy for pathologies with gene expression dysregulation.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Chemistry, Physical
Maxime Durelle, Sophie Charton, Frederic Gobeaux, Corinne Chevallard, Luc Belloni, Fabienne Testard, Sylvain Trepout, David Carriere
Summary: Crystallization from solution often involves transient, non-crystalline states such as reactant-rich liquid droplets and amorphous particles. In this study, the crystallization process of cerium oxalate was investigated and a metastable chemical equilibrium between liquid droplets and solid amorphous particles was observed. Contrary to expectations, reactant-rich droplets do not transform into amorphous solids, but instead, amorphous and reactant-rich liquid phases coexist for a certain period of time.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Sabyasachi Patra, Fabienne Testard, Frederic Gobeaux, Lorette Sicard, Delphine Shaming, Sophie Le Caer, Antoine Thill
Summary: By coupling bare plasmonic gold nanoparticles (GNPs) with hybrid aluminosilicate nanotubes (Imo-CH3), the photocatalytic activity of the nanotubes is significantly enhanced, with a large part of water reduction occurring directly on the gold surface. The coupling mechanism strongly influences the initial H-2 production rate, which can be greatly increased compared to bare Imo-CH3. This hybrid photocatalytic nano-reactor benefits from a synergy of polarization and confinement effects, facilitating efficient H-2 production.
Article
Chemistry, Physical
Amandine Gendron, Severine Domenichini, Sandrine Zanna, Frederic Gobeaux, Christophe Piesse, Didier Desmaele, Mariana Varna
Summary: Peptides, such as cyclosporin A (CsA) and Elamipretide, have shown potential in preventing ischemia/reperfusion (I/R) injury. However, their rapid degradation in the bloodstream limits their effectiveness. To address this issue, a new bioconjugate of Elamipretide was developed by coupling it with polyisoprenoid lipids, which demonstrated self-assembling ability. The resulting nanoparticles, combined with CsA, showed low cytotoxicity and antioxidant capacity, making them a promising approach for targeting cardiac I/R lesions.
Article
Chemistry, Multidisciplinary
Frederic Gobeaux, Joelle Bizeau, Firmin Samson, Laurent Marichal, Isabelle Grillo, Frank Wien, Semen O. Yesylevsky, Christophe Ramseyer, Marie Rouquette, Sinda Lepetre-Mouelhi, Didier Desmaele, Patrick Couvreur, Patrick Guenoun, Jean-Philippe Renault, Fabienne Testard
