Article
Chemistry, Analytical
Lingli Xuan, Wenyan Liao, Meifang Wang, Huaxu Zhou, Yao Ding, Fei Yan, Jiyang Liu, Hongliang Tang, Fengna Xi
Summary: This study presents a simple strategy to fabricate VMSF films on common sensing electrodes without the use of any chemical adhesive, aiming to develop superior VMSF-based electrochemical sensors. The developed VMSF/p-GCE exhibits much higher electrochemical response to biomarkers and can detect dopamine in real serum samples with exceptional sensitivity and selectivity.
Review
Chemistry, Multidisciplinary
Alain Walcarius
Summary: Supramolecular soft-templating approaches have revolutionized the generation of mesoporous materials with unique features, such as uniform pore structure, large surface area, high pore volume, variability of composition, and ease of functionalization. The electrochemically assisted self-assembly (EASA) method provides a fast and versatile way to generate highly ordered and hexagonally packed mesopore channels, allowing for the development of functionalized oriented films carrying a wide range of organo-functional groups. This method has opened perspectives for future developments and applications in various fields.
ACCOUNTS OF CHEMICAL RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Xinjie Wei, Xuan Luo, Shuai Xu, Fengna Xi, Tingting Zhao
Summary: Fast, convenient, and highly sensitive detection of antibiotics is crucial to prevent their overuse and potential harm. In this study, a flexible electrochemiluminescence (ECL) sensor based on vertically ordered mesoporous silica nanochannel film (VMSF) was developed for sensitive detection of clindamycin. The sensor exhibited high signal stability and antifouling characteristic, allowing direct analysis of clindamycin in real biological samples.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Meifang Wang, Jing Lin, Jiawei Gong, Mingchen Ma, Hongliang Tang, Jiyang Liu, Fei Yan
Summary: The study demonstrates the rapid and sensitive electrochemical detection of doxorubicin using electrochemically pretreated glassy carbon electrodes modified with vertically-ordered mesoporous silica films. The sensor showed ultra-high sensitivity, low limit of detection, wide linear range, and the ability for direct and reliable detection of doxorubicin in human whole blood without complex sample pretreatments, thanks to the excellent anti-fouling and anti-interference properties of the VMSF.
Article
Chemistry, Multidisciplinary
Yupu Liu, Jinxiu Wang, Wei Teng, Chin-Te Hung, Yunpu Zhai, Dengke Shen, Wei Li
Summary: This study developed vertically oriented mesoporous coatings with tunable surface properties and pore sizes for efficient removal of organic pollutants. The coatings showed high adsorption capacity and universality, with exceptional performance in removing microcystin-LR. They also overcame challenges of stability and reusability, paving a new route for high-quality coatings in water purification.
Article
Chemistry, Multidisciplinary
Su-Hwan Kim, Kwangsoo Shin, Byung-Gee Kim, Nathaniel S. S. Hwang, Taeghwan Hyeon
Summary: The combination of mesoporous silica nanoparticles (MSNs) and tyrosinase enables immediate adhesion and long-term sustainability of biological tissues, making it a promising strategy for tissue adhesives in clinical settings.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Jonathan J. Calvillo Solis, Monica Galicia Garcia, Felipe J. Gonzalez Bravo, Cesar A. Ortiz-Ledon
Summary: A chemically modified glassy carbon electrode (GCE) was used for sensitive determination of Cd(II), Pb(II) and Hg(II), achieving 97.4% surface coverage with p-propylaniline/L-Cys molecules. The nanofilm coating characterized by various techniques allowed for selective coordination and preconcentration of the metal ions, demonstrating the electrode's precision and accuracy for complex aqueous environmental matrices.
Article
Chemistry, Multidisciplinary
Kai Ma, Luoxing Yang, Jun Liu, Jiyang Liu
Summary: In this study, a reliable and miniaturized electrochemical sensor based on screen-printed carbon electrodes (SPCEs) equipped with vertically-ordered mesoporous silica-nanochannel film (VMSF) was developed to improve anti-interference ability and sensitivity. The sensor, modified with electrochemically reduced graphene oxide (ErGO) as a conductive adhesion layer, demonstrated enhanced electrocatalytic performance and enabled sensitive detection of uric acid in human whole blood with low sample consumption.
Article
Chemistry, Physical
Yuxin He, M. Arif Khan, Andrew Drake, Ramy Ghanim, Joshua Garay, Aniruddha Shirodkar, Joseph Strzalka, Qingteng Zhang, Barbara L. Knutson, Stephen E. Rankin
Summary: The development of mesoporous structure during calcination of titania-doped mesoporous silica thin films was characterized by in situ grazing-incidence small-angle X-ray scattering (GISAXS). The incorporation of titania using different methods and amounts influenced the final structure of the films, with weak Si-O-Ti bonds playing a crucial role in the sintering process. Anisotropic stress and annealing led to the merging of randomly oriented pores into vertically oriented channels with a pore diameter of around 2.3 nm. Surfactant complexation also played a role in the transformation of the structure.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Medicine, Research & Experimental
Ahmad Alkhazaleh, Sundes Elfagih, Leela Raghava Jaidev Chakka, Steven R. Armstrong, Carissa L. Comnick, Fang Qian, Aliasger K. Salem, C. Allan Guymon, Amanda J. Haes, Cristina M. P. Vidal
Summary: This study investigated the use of mesoporous silica nanoparticles (MSNs) for dental tissue biomodification. The incorporation of MSNs loaded with proanthocyanidin (PAC) improved the mechanical properties and bonding performance of dental restorative materials.
MOLECULAR PHARMACEUTICS
(2022)
Article
Chemistry, Analytical
Tongtong Zhang, Luoxiang Yang, Fei Yan, Kai Wang
Summary: This study developed a low-cost and stable electrochemical aptasensor using vertically-ordered mesoporous silica films (VMSF) for highly sensitive and direct detection of alpha fetoprotein (AFP) in human serum, which is vital for early diagnosis of hepatocellular carcinoma. VMSF, with silanol groups on the surface and regularly ordered nanopores, provides binding sites for functionalization of recognition aptamer and also possesses excellent anti-biofouling capacity. The sensing mechanism relies on the target AFP-controlled diffusion of Fe(CN)(6)(3-/4-) redox electrochemical probe through the nanochannels of VMSF, resulting in reduced electrochemical responses that are related to the AFP concentration. The developed aptasensor demonstrates a wide dynamic linear range and a low limit of detection of AFP.
Article
Chemistry, Analytical
Tongtong Zhang, Shuai Xu, Xingyu Lin, Jiyang Liu, Kai Wang
Summary: Here, we present a highly specific electrochemical aptasensor for the determination of AFB1 based on the controlled diffusion of the redox probe (Ru(NH3)(6)(3+)) through nanochannels functionalized with AFB1-specific aptamers. By utilizing the cationic permselectivity of VMSF, the inner surface of the nanochannels allows for electrostatic preconcentration of Ru(NH3)(6)(3+), leading to amplified electrochemical signals. The addition of AFB1 results in a specific interaction with the aptamer, hindering the access of Ru(NH3)(6)(3+) and causing reduced electrochemical responses, enabling quantitative determination of AFB1. The proposed aptasensor exhibits excellent detection performance, with a detection range of 3 pg/mL to 3 μg/mL and a low detection limit of 2.3 pg/mL for AFB1. Practical analysis of AFB1 in peanut and corn samples was also successfully performed using the fabricated aptasensor, yielding satisfactory results.
Article
Chemistry, Physical
Huan Chen, Weilong Li, Mi He, Xinwei Chang, Xinliang Zheng, Zhaoyu Ren
Summary: Using a facile technique, VOCNT@Co0.85Se/NF electrode with excellent performance was successfully synthesized, showing high specific capacity, good rate performance, and remarkable cyclic stability.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Chemistry, Analytical
Biuck Habibi, Ali Pashazadeh, Lotf Ali Saghatforoush
Summary: A mesoporous crystalline material with zinc metal-organic framework structure, Cu/Zn-mMOF/GCE, was synthesized by electrochemical method for electrochemical sensing of amoxicillin. The modified electrode exhibited high electrocatalytic activity towards amoxicillin oxidation, making it a promising sensor for real sample analysis.
MICROCHEMICAL JOURNAL
(2021)
Article
Materials Science, Multidisciplinary
Magdalena Laskowska, Alain Walcarius, Andrii Fedorchuk, Maciej Zubko, Lukasz Laskowski
Summary: This work presents a synthesis procedure for preparing vertically aligned mesoporous silica thin films with long nanometer-scale silver nanowires inside pores. The nanowires have a fine crystalline structure and a diameter of no more than 2 nm. The synthesis involves the use of silica nanoreactors and consists of two steps: fabricating an organically-functionalized silica thin film with regularly distributed silver ions inside vertically aligned pores, and thermally decomposing the film to form metallic crystalline nanowires. The resulting nanocomposite and initial material were characterized using electron microscopy and electrochemical techniques. The confinement provided by silica nanochannels enables the stabilization of small and ultra-thin nanowires and the formation of a hexagonal silver crystalline structure.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Chemistry, Multidisciplinary
Chunhua Zhang, Huiting Zhang, Junying Pi, Lin Zhang, Alexander Kuhn
Summary: The study introduces a method for regenerating reduced NADH using electrocatalytically active modified microparticles in a bipolar electrochemical cell. The efficiency of the system can be fine-tuned by controlling the electric field and the number of dispersed microelectrodes, offering new possibilities for bioelectrocatalytic synthesis in the bulk phase.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Alonso Gamero-Quijano, Pierre-Andre Cazade, Shayon Bhattacharya, Sarah Walsh, Gregoire Herzog, Damien Thompson, Micheal D. Scanlon
Summary: This study demonstrates that electrified aqueous|organic interfaces can be used as a suitable biomimetic platform to study and compare the accelerated electrocatalytic activity of cytochrome c in the presence of denaturing agents.
CHEMICAL COMMUNICATIONS
(2022)
Article
Engineering, Chemical
T. D. Le, D. Lasseux, L. Zhang, C. Carucci, S. Gounel, S. Bichon, F. Lorenzutti, A. Kuhn, T. Safarik, N. Mano
Summary: This work focuses on a multi-scale modeling of coupled diffusion and reaction in a porous micro electrode operating in the Direct Electron Transfer mode. By developing and validating the model, it provides an operational simple way of understanding and further optimizing the functioning of porous electrodes in DET mode.
CHEMICAL ENGINEERING SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Magdalena Kaliszczak, Pierrick Durand, Emmanuel Wenger, Manuel Dossot, Franca Jones, Damien W. M. Arrigan, Gregoire Herzog
Summary: Controlled formation of cocrystals of caffeine and 1-hydroxy-2-naphthoic acid was achieved at the interface between two immiscible electrolyte solutions under chemical polarisation, leading to the selective cocrystallisation as confirmed by X-ray diffraction and Raman spectroscopy. Positive interfacial potentials favored the formation of a specific polymorphic form of caffeine:1-hydroxy-2-naphthoic acid cocrystal. This electrochemically controlled cocrystallisation approach opens up new possibilities for drug development.
Article
Chemistry, Physical
Wahid Ullah, Gregoire Herzog, Neus Vila, Alain Walcarius
Summary: Vertically aligned silica nanochannel membranes modified indium-tin oxide electrodes have been produced using electrochemically assisted self-assembly of cationic surfactants and concomitant polycondensation of silica precursors. The polyaniline nanofilaments grown through these nanochannels exhibited electrochromic properties, with faster electrochromic behavior observed in template-free nanowire arrays.
FARADAY DISCUSSIONS
(2022)
Article
Materials Science, Multidisciplinary
Xiaonan Sun, Wahid Ullah, Jean-Christophe Lacroix, Alain Walcarius, Gregoire Herzog, Neus Vila
Summary: Aniline is electropolymerized through mesoporous silica nanopores orthogonally oriented on indium-tin oxide (ITO). The electronic transport properties of PANI@SiO2 are studied by Conductive Atomic Force Microscopy (C-AFM), showing different behaviors such as linear, flat, and non-linear I/V curves. The non-linear curves are attributed to the formation of molecular junctions where the C-AFM tip in contact with the nanopores acts as the top electrode and vertical PANI wires fill the SiO2 channels.
ECS JOURNAL OF SOLID STATE SCIENCE AND TECHNOLOGY
(2022)
Article
Electrochemistry
Wassim El Housseini, Francois Lapicque, Steve Pontvianne, Neus Vila, Ievgen Mazurenko, Alain Walcarius, Mathieu Etienne
Summary: The electrochemical regeneration of reduced form of NADH was achieved in a hybrid flow reactor. The stable immobilization of all catalysts, including a rhodium catalyst, was carefully optimized. The system showed high activity and stability, allowing for efficient biosynthesis reactions with low cofactor concentration.
Article
Chemistry, Multidisciplinary
Julius Gajdar, Gregoire Herzog, Mathieu Etienne
Summary: Accurate and rapid on-site analysis of free SO2 content is crucial in winemaking. Researchers have developed an amperometric sensor based on commercially available screen-printed electrodes and an electrochemical oxygen filter. The sensor showed similar precision and accuracy compared to the standard method, with the advantage of no interference from oxidizable species.
Article
Nanoscience & Nanotechnology
Weiwei Li, Chunhua Zhang, Ziman Zheng, Xiaoyu Zhang, Lin Zhang, Alexander Kuhn
Summary: Electrochemical regeneration of the reduced form of NADH cofactor using a metal-organic framework film as the electrode enables tunable electrocatalytic activity for efficient enzymatic synthesis of valuable chemicals.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Samuel Ahoulou, Clara Richart, Cedric Carteret, Sebastien Pillet, Neus Vila, Alain Walcarius
Summary: Iron (II) tris(2,2 '-bipyridine) complexes have been synthesized and immobilized in nanostructured silica thin films using organosulfonate moieties. The immobilization process does not affect the optical and electrochemical properties of the complexes.
Article
Biochemistry & Molecular Biology
Jianren Wang, Tianshuo Yang, Neus Vila, Alain Walcarius
Summary: The study focuses on planar energy storage devices, which are low-cost, high-capacity, and have satisfactory flexibility. Graphene, as an active component, has a tension between its high conductivity and ease of implementation. A facile Top-down method has been proposed to prepare graphene planar electrodes using laser-cutting patterned scotch tape, showing decent energy storage performance and versatility for meeting growing energy storage demands.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Xiaoyu Zhang, Zhenzhen Huang, Lin Zhang, Wensheng Yang
Summary: This study systematically investigated the role of sodium hydroxide in the formation and emission properties of Au nanoclusters. It was found that the activity of the gold precursor and the emission properties of the resulting Au nanoclusters depend on the addition time of sodium hydroxide. Additionally, the reducing ability of BSA is dependent on the concentration of sodium hydroxide in the reaction solution. By optimizing the addition time and concentration of sodium hydroxide used, Au nanoclusters with improved emission properties were successfully synthesized under relatively low BSA concentrations, showing improved performance in sensing Cu2+ ions.
Article
Chemistry, Multidisciplinary
Nazanin Ghaheri, Benjamin J. J. Austen, Gregoire Herzog, Mark Ogden, Franca Jones, Damien W. M. Arrigan
Summary: This study investigates crystallisation at the interface between two immiscible solutions by observing the spontaneous transfer of ions. The results demonstrate the ability to form ionic crystalline materials by exploiting ion transfer processes at the interface between immiscible liquids. The influence of a neutral ionophore in the organic phase on spontaneous formation of BaSO4 was also studied.