Tubastatin A potently inhibits GPX4 activity to potentiate cancer radiotherapy through boosting ferroptosis
出版年份 2023 全文链接
标题
Tubastatin A potently inhibits GPX4 activity to potentiate cancer radiotherapy through boosting ferroptosis
作者
关键词
-
出版物
Redox Biology
Volume 62, Issue -, Pages 102677
出版商
Elsevier BV
发表日期
2023-03-17
DOI
10.1016/j.redox.2023.102677
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition
- (2023) Alvan Amos et al. BMC CANCER
- RBBP4 regulates the expression of the Mre11-Rad50-NBS1 (MRN) complex and promotes DNA double-strand break repair to mediate glioblastoma chemoradiotherapy resistance
- (2023) Junjie Li et al. CANCER LETTERS
- STC2 activates PRMT5 to induce radioresistance through DNA damage repair and ferroptosis pathways in esophageal squamous cell carcinoma
- (2023) Kan Jiang et al. Redox Biology
- NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8
- (2023) Annadurai Anandhan et al. Science Advances
- Hypoxia-Induced Autophagy Is Involved in Radioresistance via HIF1A-Associated Beclin-1 in Glioblastoma Multiforme
- (2023) Jielin Wei et al. Heliyon
- Ferroptosis and tumor immunotherapy: A promising combination therapy for tumors
- (2023) Huazhong Cai et al. Frontiers in Oncology
- PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis
- (2022) Hai-Liang Zhang et al. NATURE CELL BIOLOGY
- CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4
- (2022) Peng Liao et al. CANCER CELL
- Cell Signaling Pathways That Promote Radioresistance of Cancer Cells
- (2022) Michel M. Ouellette et al. Diagnostics
- SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes
- (2022) Wang Zheng et al. Autophagy
- SOCS2-enhanced ubiquitination of SLC7A11 promotes ferroptosis and radiosensitization in hepatocellular carcinoma
- (2022) Qianping Chen et al. CELL DEATH AND DIFFERENTIATION
- NOD2 ‐mediated HDAC6 / NF ‐κb signalling pathway regulates ferroptosis induced by extracellular histone H3 in acute liver failure
- (2022) Qian Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- PARPi treatment enhances radiotherapy-induced ferroptosis and antitumor immune responses via the cGAS signaling pathway in colorectal cancer
- (2022) Dongya Shen et al. CANCER LETTERS
- Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation
- (2022) Fabienne Müller et al. CELL DEATH AND DIFFERENTIATION
- The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis
- (2022) Zhi Lin et al. Nature Communications
- The role of microRNA-induced apoptosis in diverse radioresistant cancers
- (2022) Leili Darvish et al. CELLULAR SIGNALLING
- Ferroptosis: mechanisms, biology and role in disease
- (2021) Xuejun Jiang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Breast cancer
- (2021) Sibylle Loibl et al. LANCET
- DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer
- (2021) Chao Mao et al. NATURE
- Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers
- (2020) Ling F. Ye et al. ACS Chemical Biology
- The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression
- (2020) Guang Lei et al. CELL RESEARCH
- Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis
- (2020) Yilong Zou et al. Nature Chemical Biology
- Cysteine depletion induces pancreatic tumor ferroptosis in mice
- (2020) Michael A. Badgley et al. SCIENCE
- Lymph protects metastasizing melanoma cells from ferroptosis
- (2020) Jessalyn M. Ubellacker et al. NATURE
- Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis
- (2020) Nandini Verma et al. Science Advances
- Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1
- (2020) Bo Yan et al. MOLECULAR CELL
- Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis
- (2020) Junmei Yi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting Ferroptosis to Iron Out Cancer
- (2019) Behrouz Hassannia et al. CANCER CELL
- CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy
- (2019) Weimin Wang et al. NATURE
- Radiotherapy and immunotherapy promote tumoral lipid oxidation and ferroptosis via synergistic repression of SLC7A11
- (2019) Xueting Lang et al. Cancer Discovery
- FSP1 is a glutathione-independent ferroptosis suppressor
- (2019) Sebastian Doll et al. NATURE
- The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
- (2019) Kirill Bersuker et al. NATURE
- GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling
- (2019) Vanessa A. N. Kraft et al. ACS Central Science
- Cancer Radiosensitizers
- (2018) Hao Wang et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Targeting autophagy for combating chemoresistance and radioresistance in glioblastoma
- (2018) Matthew A. Taylor et al. APOPTOSIS
- BAP1 links metabolic regulation of ferroptosis to tumour suppression
- (2018) Yilei Zhang et al. NATURE CELL BIOLOGY
- Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
- (2017) Vasanthi S. Viswanathan et al. NATURE
- HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness
- (2017) Janina Leyk et al. Cell Death & Disease
- Ferroptosis as a p53-mediated activity during tumour suppression
- (2015) Le Jiang et al. NATURE
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Image-guided radiotherapy: from current concept to future perspectives
- (2012) David A. Jaffray Nature Reviews Clinical Oncology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now