Review
Microbiology
Lizdany Florez-Alvarez, Edmarcia Elisa de Souza, Viviane Fongaro Botosso, Danielle Bruna Leal de Oliveira, Paulo Lee Ho, Carlos Pelleschi Taborda, Giuseppe Palmisano, Margareth Lara Capurro, Joao Renato Rebello Pinho, Helena Lage Ferreira, Paola Minoprio, Eurico Arruda, Luis Carlos de Souza Ferreira, Carsten Wrenger, Edison Luiz Durigon
Summary: This article discusses the pathogenesis and treatment options for viral hemorrhagic fevers caused by hemorrhagic fever viruses (HFVs), as well as the potential for these viruses to cause global emergencies and factors favoring their spread beyond their original niches.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Public, Environmental & Occupational Health
Veronica N. E. Malange, Gitte Hedermann, Ulrik Lausten-Thomsen, Steen Hoffmann, Marianne Voldstedlund, Anna J. M. Aabakke, Anna K. K. Eltvedt, Jorgen S. Jensen, Morten Breindahl, Lone Krebs, Michael Christiansen, Paula L. L. Hedley
Summary: In the past decade, there have been numerous infectious disease outbreaks worldwide, which have had significant effects on perinatal health, including increased risk of preterm delivery and the delivery of low birth weight or small for gestational age babies. Severe perinatal outcomes, such as perinatal and infant death, have also been observed in relation to various infectious diseases. It is important to monitor perinatal health and collect systematic data to understand the implications of these diseases for pregnant women and their unborn infants.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Virology
Suresh Kuchipudi, Deanna Behring, Ruth Nissly, Shubhada K. Chothe, Abhinay Gontu, Abirami Ravichandran, Ty Butler
Summary: The Emerging Animal Infectious Disease Conference (EAIDC) held at Pennsylvania State University brought together world-leading experts in the field to review past experiences dealing with high-consequence animal infectious diseases. The conference emphasized the importance of livestock biosecurity and the need for advanced diagnostics to detect pathogens. It also highlighted the significance of the One Health approach in addressing emerging animal and human infectious diseases.
Review
Medicine, General & Internal
Abhilasha Pankaj Boruah, Kiran T. Thakur
Summary: The rapid spread of arboviral infections, which are transmitted by arthropods, has become a global health concern. These infections can cause a wide range of clinical presentations, from asymptomatic infection to severe neurological diseases. The pathogenesis of arboviral infections is still being investigated, but shared neuroanatomical pathways among these viruses may provide insights for future therapeutic targets. It is crucial to consider the potential role of global climate change and human environmental disruption in the shifting infection transmission patterns and distribution of arboviral vectors when assessing patients with encephalitic presentations.
POSTGRADUATE MEDICAL JOURNAL
(2023)
Review
Pharmacology & Pharmacy
Adam Bess, Frej Berglind, Supratik Mukhopadhyay, Michal Brylinski, Nicholas Griggs, Tiffany Cho, Chris Galliano, Kishor M. Wasan
Summary: Artificial intelligence and other in silico techniques can improve the efficiency and cost-effectiveness of drug discovery, and it is a crucial field for addressing emerging infectious diseases.
DRUG DISCOVERY TODAY
(2022)
Article
Microbiology
Olesia V. Ohlopkova, Sergey A. Yakovlev, Kabwe Emmanuel, Alexey A. Kabanov, Dmitry A. Odnoshevsky, Mikhail Yu. Kartashov, Alexey D. Moshkin, Igor V. Tuchkov, Nikita Yu. Nosov, Andrey A. Kritsky, Milana A. Agalakova, Yuriy N. Davidyuk, Svetlana F. Khaiboullina, Sergey P. Morzunov, Magasuba N'Fally, Sanaba Bumbali, Mamadou Fode Camara, Mamadou Yero Boiro, Alexander P. Agafonov, Elena V. Gavrilova, Rinat A. Maksyutov
Summary: This study aims to monitor the presence of Coxiella burnetii in ticks collected from small mammals and cattle in the Republic of Guinea. The results showed that bacterial DNA was detected in 11 small mammals and 695 tick samples, indicating that ticks are the main transmitters of C. burnetii in Guinea.
Review
Biochemistry & Molecular Biology
Dorit Trudler, Swagata Ghatak, Stuart A. Lipton
Summary: Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and Huntington's disease, represent a significant social and economic burden due to increasing prevalence and lack of effective therapies. Lack of reliable models has hindered the development of treatments, but human-induced pluripotent stem cell technology offers a promising alternative to complement animal models for disease modeling and drug discovery.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Syed A. A. Rizvi, George P. Einstein, Orien L. Tulp, Frantz Sainvil, Rolando Branly
Summary: Infectious diseases pose a threat to global human health, and overcoming them requires constant efforts and research. However, microbial adaptation and mutation lead to antibiotic and antiviral resistance. Treating infections faces challenges, necessitating multidisciplinary collaboration to develop more effective and versatile therapies. Natural medicine has proven effective, but the full potential of natural resources remains untapped, warranting continuous research and analysis.
Review
Biology
Rongzhang Hao, Yuqi Liu, Wanzhu Shen, Rongtao Zhao, Bo Jiang, Hongbin Song, Muyang Yan, Hui Ma
Summary: Emerging infectious diseases and other biosecurity risks pose significant threats to humans and the environment. Current surveillance systems face challenges and require improvements in technology, management, and international cooperation. A global strategy of meaningful cooperation is needed, which includes integrating surveillance at all levels and interdisciplinary management, to effectively mitigate biosecurity risks.
SCIENCE CHINA-LIFE SCIENCES
(2022)
Review
Chemistry, Multidisciplinary
Zhaoting Li, Yixin Wang, Yingyue Ding, Lauren Repp, Glen S. Kwon, Quanyin Hu
Summary: Immunotherapy plays a crucial role in treating diseases, but its application is hindered by limited response rates and systemic side effects. Using natural cells as carriers can reduce immunogenicity and toxicity, while controlling their spatiotemporal distribution can enhance treatment efficacy and minimize side effects.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Biodiversity Conservation
Yingying X. G. Wang, Kevin D. Matson, Luca Santini, Piero Visconti, Jelle P. Hilbers, Mark A. J. Huijbregts, Yanjie Xu, Herbert H. T. Prins, Toph Allen, Zheng Y. X. Huang, Willem F. de Boer
Summary: The composition of wildlife assemblages plays a crucial role in transmission dynamics of infectious diseases, impacting the risk of both density-dependent and frequency-dependent diseases. Changes in disease risk are influenced by biodiversity, climate change, and habitat loss.
GLOBAL CHANGE BIOLOGY
(2021)
Article
Infectious Diseases
James Gong, Christine Griebsch, Nicolle Kirkwood, Jacqueline M. Norris, Michael P. Ward
Summary: This retrospective study of a canine leptospirosis outbreak in Sydney in 2017 found that the presence of clusters of the disease were likely due to environmental factors rather than host or pathogen factors.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Biology
Scott L. Nuismer, Andrew J. Basinski, Courtney Schreiner, Alexander Whitlock, Christopher H. Remien
Summary: The ecology and life history of wild animals influence their potential to harbor infectious disease. Average lifespan and viral mutation rate play a crucial role in the likelihood of animals serving as reservoirs for human infectious disease. Persistent infections and transient immune responses within the reservoir are more likely to lead to the emergence of viral pathogens.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2022)
Article
Immunology
Patricio Oyarzun, Manju Kashyap, Victor Fica, Alexis Salas-Burgos, Faviel F. Gonzalez-Galarza, Antony McCabe, Andrew R. Jones, Derek Middleton, Bostjan Kobe
Summary: Emerging infectious diseases caused by viruses are on the rise, with COVID-19 pandemic highlighting the urgency for effective vaccination strategies. HLA molecules are central in the immune system, influencing vaccine-induced immune responses, particularly due to variability across different ethnic groups.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Immunology
Jose E. Belizario, Joel Faintuch, Miguel Garay Malpartida
Summary: Exhaled breath contains thousands of metabolites and volatile organic compounds that can serve as biomarkers for various human diseases. By studying VOC fingerprints generated by cellular and microbial metabolic pathways, potential biomarkers for disease diagnosis and classification can be identified.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)