3D cardiac μtissues within a microfluidic device with real-time contractile stress readout

Food for thought... on the economics of animal testing

(2016) Annamaria Bottini   ALTEX-Alternatives to Animal Experimentation

Embedded 3D Photopatterning of Hydrogels with Diverse and Complex Architectures for Tissue Engineering and Disease Models

(2015) Shruti Krishna Davey et al.   TISSUE ENGINEERING PART C-METHODS

Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications

(2015) Anurag Mathur et al.   Scientific Reports

Mineralized gelatin methacrylate-based matrices induce osteogenic differentiation of human induced pluripotent stem cells

(2014) Heemin Kang et al.   Acta Biomaterialia

3D Traction Stresses Activate Protease-Dependent Invasion of Cancer Cells

(2014) Aereas Aung et al.   BIOPHYSICAL JOURNAL

A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening

(2014) Christopher Heylman et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

(2014) Gang Wang et al.   NATURE MEDICINE

Microfluidic heart on a chip for higher throughput pharmacological studies

(2013) Ashutosh Agarwal et al.   LAB ON A CHIP

A Novel 3D Fibril Force Assay Implicates Src in Tumor Cell Force Generation in Collagen Networks

(2013) Robert J. Polackwich et al.   PLoS One

Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip

(2013) M. L. McCain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and formulation of functional pluripotent stem cell-derived cardiac microtissues

(2013) N. Thavandiran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ischemia/reperfusion injury of primary porcine cardiomyocytes in a low-shear microfluidic culture and analysis device

(2011) Grishma Khanal et al.   ANALYST

Ensembles of engineered cardiac tissues for physiological and pharmacological study: Heart on a chip

(2011) Anna Grosberg et al.   LAB ON A CHIP

A Microfabricated Platform to Measure and Manipulate the Mechanics of Engineered Cardiac Microtissues

(2011) Thomas Boudou et al.   TISSUE ENGINEERING PART A

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Microfluidic Cardiac Cell Culture Model (μCCCM)

(2010) Guruprasad A. Giridharan et al.   ANALYTICAL CHEMISTRY

Cell-laden microengineered gelatin methacrylate hydrogels

(2010) Jason W. Nichol et al.   BIOMATERIALS

Development of a Drug Screening Platform Based on Engineered Heart Tissue

(2010) Arne Hansen et al.   CIRCULATION RESEARCH

Contractile tension and beating rates of self-exciting monolayers and 3D-tissue constructs of neonatal rat cardiomyocytes

(2009) P. Linder et al.   MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

An improved protocol for primary culture of cardiomyocyte from neonatal mice

(2008) P. Sreejit et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Quantitative evaluation of cardiomyocyte contractility in a 3D microenvironment

(2008) Jinseok Kim et al.   JOURNAL OF BIOMECHANICS

Methodological Quality of Animal Studies of Neuroprotective Agents Currently in Phase II/III Acute Ischemic Stroke Trials

(2008) Maria Philip et al.   STROKE