One-Pot Chemoenzymatic Cascade for Labeling of the Epigenetic Marker 5-Hydroxymethylcytosine

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers

(2015) Michael Christoph Haffner et al.   Oncotarget

Spectroscopic Quantification of 5-Hydroxymethylcytosine in Genomic DNA

(2014) Tamar Shahal et al.   ANALYTICAL CHEMISTRY

New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine

(2014) Erika L. Moen et al.   IMMUNOLOGICAL REVIEWS

Lighting Up Individual DNA Damage Sites by In Vitro Repair Synthesis

(2014) Shahar Zirkin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation

(2014) Udo Müller et al.   NUCLEIC ACIDS RESEARCH

Toward Single-Molecule Optical Mapping of the Epigenome

(2013) Michal Levy-Sakin et al.   ACS Nano

Optical detection of epigenetic marks: sensitive quantification and direct imaging of individual hydroxymethylcytosine bases

(2013) Yael Michaeli et al.   CHEMICAL COMMUNICATIONS

Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver

(2013) John P. Thomson et al.   NUCLEIC ACIDS RESEARCH

Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads

(2012) Adam B Robertson et al.   Nature Protocols

One-pot three-enzyme synthesis of UDP-GlcNAc derivatives

(2011) Yi Chen et al.   CHEMICAL COMMUNICATIONS

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

(2011) C. E. Nestor et al.   GENOME RESEARCH

Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells

(2011) Yufei Xu et al.   MOLECULAR CELL

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

(2011) Tian-Peng Gu et al.   NATURE

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

(2011) Gabriella Ficz et al.   NATURE

5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

(2011) Keith E Szulwach et al.   NATURE NEUROSCIENCE

Quantification of the Sixth DNA Base Hydroxymethylcytosine in the Brain

(2010) Martin Münzel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cu-free click cycloaddition reactions in chemical biology

(2010) John C. Jewett et al.   CHEMICAL SOCIETY REVIEWS

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

(2010) Chun-Xiao Song et al.   NATURE BIOTECHNOLOGY

Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates

(2010) Daniel Globisch et al.   PLoS One

A survey of chemical methods for sugar-nucleotide synthesis

(2009) Gerd K. Wagner et al.   NATURAL PRODUCT REPORTS

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE