Article
Surgery
Kyu-Ho Yi, Hyung-Jin Lee, Hye-Won Hur, Kyle K. Seo, Hee-Jin Kim
Summary: This study reviewed the anatomical considerations when injecting botulinum neurotoxin and provided optimal injection sites and technique for the temporalis and masseter muscles. It also proposed external anatomical landmarks for injection in frequently injected muscles of the face.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Article
Biochemistry & Molecular Biology
Linhui Ni, Hanze Chen, Xinxin Xu, Di Sun, Huaying Cai, Li Wang, Qiwen Tang, Yonggang Hao, Shuxia Cao, Xingyue Hu
Summary: BoNT/A inhibits the excitatory neurons projecting from facial motoneurons to the ventrolateral periaqueductal grey (vlPAG) through axonal retrograde transport and cell-to-cell transcytosis, thus regulating depressive-like phenotypes in mice subjected to chronic restraint stress (CRS).
CELL AND BIOSCIENCE
(2023)
Article
Surgery
Yue Yin, Tong Li, Chunfang Wang, Qiaoxin Ma, Xing Fan
Summary: Botulinum toxin A injection into the platysma and the depressor anguli oris muscles is a safe, convenient, and effective treatment to correct the complication of facial flaccidity and sagging after masseter reduction. The study found that 96% of patients were satisfied with the treatment outcome, with only one patient considering it unsatisfactory. Physician evaluation showed significant improvement in all patients, including the one who considered the treatment outcome unsatisfactory.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Surgery
D. Hernandez Herrero, E. Abdel Muti Garcia, J. Lopez Araujo, E. Alfonso Barrera, S. Moraleda Perez
Summary: Facial palsy (FP) is a common neuropathy, and botulinum toxin A (BoNT-A) has been found to be effective in treating its sequelae. However, the cost of treating FP with BoNT-A has not been studied. This retrospective review analyzed the costs and frequency of BoNT-A treatment for FP sequelae in a clinic in 2017. The average annual cost per patient was 124.31 euros, and patients required treatment every 124 days.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2022)
Review
Rehabilitation
Helena Tavares, Mafalda Oliveira, Rui Costa, Hugo Amorim
Summary: This review discusses the treatment patterns of botulinum toxin type A in patients with postparetic synkinesis. The study found that the treatment is effective in improving symptoms and has minimal adverse effects. However, there is a lack of standardized treatment protocols.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2022)
Article
Dermatology
Yoriko Ando, Yuichiro Ohshima, Takeshi Yanagishita, Hitomi Watanabe, Yasuhiko Tamada, Masashi Akiyama, Daisuke Watanabe
Summary: This study demonstrates that BTX-A therapy is a safe and effective treatment for HFH, reducing sweat production and improving patients' quality of life.
JOURNAL OF DERMATOLOGY
(2022)
Article
Behavioral Sciences
Qilin Zhang, Wenqi Wu, Yuxin Fan, Yang Li, Jing Liu, Yingying Xu, Caixia Jiang, Zhen Tang, Cong Cao, Tong Liu, Li-Hua Chen, Hua Hu, Weifeng Luo
Summary: This study compared the efficacy and side effects of BoNT/A and sertraline in the treatment of depression, finding that BoNT/A has significant antidepressant effects comparable to sertraline, with an earlier onset time and less side effects.
BRAIN AND BEHAVIOR
(2021)
Article
Multidisciplinary Sciences
Tae-Hyeon Cho, Ju-Eun Hong, Hun-Mu Yang
Summary: In this study, the dominant fibers within each compartment of the subscapularis muscle were determined using immunohistochemistry with fresh cadavers. The results showed distinct fascia demarcating the superior and inferior compartments of the muscle. The innervation of the muscle by the upper and lower subscapular nerves was also observed, and the densities of type I and type II fibers were found to differ between the compartments.
SCIENTIFIC REPORTS
(2023)
Review
Food Science & Technology
Carla de Sanctis Pecora, Danielle Shitara
Summary: The article discusses the importance of using Botulinum toxin type A in unilateral peripheral facial nerve palsy and emphasizes the correct technique to improve patients' quality of life.
Article
Food Science & Technology
Yan Tereshko, Chiara Dalla Torre, Christian Lettieri, Enrico Belgrado, Gian Luigi Gigli, Mariarosaria Valente
Summary: A 51-year-old woman with refractory Complex Regional Pain Syndrome type I (CRPS-I) involving her left hand and forearm was treated with subcutaneous injections of BoNT/A. The treatments, performed every 3 months for a total of six times, were able to effectively improve pain and motor impairment; however, the duration of the effect was limited to only a few months. BoNT/A could improve patients' quality of life with CRPS, but further extensive clinical studies are needed to determine its role in clinical practice.
Review
Medicine, General & Internal
Giuseppina Malcangi, Assunta Patano, Carmela Pezzolla, Lilla Riccaldo, Antonio Mancini, Chiara Di Pede, Alessio Danilo Inchingolo, Francesco Inchingolo, Ioana Roxana Bordea, Gianna Dipalma, Angelo Michele Inchingolo
Summary: Botulinum toxin (BTA) is a bacterial-derived extract that inhibits muscle contraction by affecting the absorption of acetylcholine. It has been widely used in aesthetic and general medicine, and recent research has explored its application for addressing bruxism.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Food Science & Technology
Francesco Bono, Maria Rosaria Mazza, Giuseppe Magro, Giorgio Spano, Giovanni Idone, Vincenzo Laterza, Denise Tedeschi, Francesco Pucci, Antonio Gambardella, Alessia Sarica
Summary: In this study, the efficacy of an individualized technique of subcutaneous injection of BoNT-A targeted (SjBoT) to the occipital or trigeminal skin area in non-responder patients with chronic migraine was evaluated. The results showed that the SjBoT injection paradigm significantly reduced monthly headache days, improved disease severity and functional impairment in patients who had not previously responded to intramuscular injections of BoNT-A.
Review
Food Science & Technology
Shu-Yu Wu, Shang-Jen Chang, Stephen Shei-Dei Yang, Chun-Kai Hsu
Summary: The study evaluated the use of BTX-A injection in children with medically refractory neurogenic bladder, finding it to be a safe and effective treatment option. Improvements in clinical and urodynamic parameters were observed as the main outcomes of the treatment.
Article
Surgery
Andrea Ferri, Francesca Zito, Giorgia Menapace, Cecilia Zannoni, Michela Bergonzani, Giuseppe Perlangeli, Bernardo Bianchi
Summary: Although neuromuscular gracilis transplantation is the best choice for facial reanimation in patients with congenital or inveterate palsy, the results are not completely satisfactory. Ancillary procedures developed to achieve better symmetry of the smile and reduce the hypercontractility of the transplanted muscle have been reported. However, the intramuscular injection of botulinum toxin has not been described for this purpose.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2023)
Review
Food Science & Technology
Anna Campanati, Emanuela Martina, Stamatis Gregoriou, George Kontochristopoulos, Matteo Paolinelli, Federico Diotallevi, Giulia Radi, Ivan Bobyr, Barbara Marconi, Giulio Gualdi, Paolo Amerio, Annamaria Offidani
Summary: Forehead hyperhidrosis has a significant impact on patients' quality of life. IncoBTX-A therapy shows promise in treating this condition, although long-term efficacy and safety data are limited. This single-center study describes the experience of treating five patients with IncoBTX-A for forehead hyperhidrosis. Significant anhidrotic effects were observed after 4 weeks of treatment, lasting approximately 36 weeks, and resulted in improved symptoms and quality of life for all patients.
