Divide and conquer: broadly neutralizing antibody combinations for improved HIV-1 viral coverage

Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency

(2023) Baoshan Zhang et al.   mAbs

Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys

(2022) Amarendra Pegu et al.   Cell Reports

Combination anti-HIV antibodies provide sustained virological suppression

(2022) Michael C. Sneller et al.   NATURE

Prolonged viral suppression with anti-HIV-1 antibody therapy

(2022) Christian Gaebler et al.   NATURE

Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial

(2022) Boris Julg et al.   NATURE MEDICINE

Broadly neutralizing antibodies against HIV-1 and concepts for application

(2022) Henning Gruell et al.   Current Opinion in Virology

Design of an optimal combination therapy with broadly neutralizing antibodies to suppress HIV-1

(2022) Colin LaMont et al.   eLife

Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition

(2022) Peter B. Gilbert et al.   NATURE MEDICINE

A calculated risk: Evaluating HIV resistance to the broadly neutralising antibodies10-1074 and 3BNC117

(2022) Panagiota Zacharopoulou et al.   Current Opinion in HIV and AIDS

Pharmacokinetics and predicted neutralisation coverage of VRC01 in HIV-uninfected participants of the Antibody Mediated Prevention (AMP) trials

(2021) Yunda Huang et al.   EBioMedicine

Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition

(2021) Lawrence Corey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Broadly Neutralizing Antibodies for HIV-1 Prevention

(2021) Stephen R. Walsh et al.   Frontiers in Immunology

Vaccines and Broadly Neutralizing Antibodies for HIV-1 Prevention

(2020) Kathryn E. Stephenson et al.   Annual Review of Immunology

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

(2019) Christine A. Bricault et al.   Cell Host & Microbe

Broadly neutralizing antibodies for the treatment and prevention of HIV infection

(2019) Marina Caskey   Current Opinion in HIV and AIDS

Broadly neutralizing antibodies for treatment and prevention of HIV-1 infection

(2018) Yehuda Z. Cohen et al.   Current Opinion in HIV and AIDS

Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections

(2018) Kshitij Wagh et al.   PLoS Pathogens

Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals

(2018) Yotam Bar-On et al.   NATURE MEDICINE

Identification and specificity of broadly neutralizing antibodies against HIV

(2017) Laura E. McCoy et al.   IMMUNOLOGICAL REVIEWS

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

(2017) Ling Xu et al.   SCIENCE

Engineered Bispecific Antibodies with Exquisite HIV-1-Neutralizing Activity

(2016) Yaoxing Huang et al.   CELL

Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

(2016) Elise Landais et al.   PLoS Pathogens

Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection

(2016) Kshitij Wagh et al.   PLoS Pathogens

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

(2015) Laura E. McCoy et al.   PLoS Pathogens