SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry

Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program

(2022) Carlos Jiménez et al.   Molecular Cancer

Single-cell profiling of peripheral neuroblastic tumors identifies an aggressive transitional state that bridges an adrenergic-mesenchymal trajectory

(2022) Xiaojun Yuan et al.   Cell Reports

Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma

(2021) Elena A Afanasyeva et al.   Life Science Alliance

EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma

(2021) Adam D. Durbin et al.   Cancer Discovery

MEIS2 Is an Adrenergic Core Regulatory Transcription Factor Involved in Early Initiation of TH-MYCN-Driven Neuroblastoma Formation

(2021) Jolien De Wyn et al.   Cancers

Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function

(2020) Svetlana O. Dodonova et al.   NATURE

Epigenomic profiling of neuroblastoma cell lines

(2020) Kristen Upton et al.   Scientific Data

ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression

(2020) Hui Shi et al.   Science Advances

A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma

(2019) Tim van Groningen et al.   Nature Communications

Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients

(2018) Pauline Depuydt et al.   JNCI-Journal of the National Cancer Institute

Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma

(2018) Rhamy Zeid et al.   NATURE GENETICS

peakC: a flexible, non-parametric peak calling package for 4C and Capture-C data

(2018) Geert Geeven et al.   NUCLEIC ACIDS RESEARCH

Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma

(2018) Presha Rajbhandari et al.   Cancer Discovery

Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients

(2018) Pauline Depuydt et al.   JNCI-Journal of the National Cancer Institute

Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry

(2018) Adam D. Durbin et al.   NATURE GENETICS

Mutational Landscapes and Phenotypic Spectrum of SWI/SNF-Related Intellectual Disability Disorders

(2018) Nina Bögershausen et al.   Frontiers in Molecular Neuroscience

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

(2018) Bieke Decaesteker et al.   Nature Communications

Neuroblastoma is composed of two super-enhancer-associated differentiation states

(2017) Tim van Groningen et al.   NATURE GENETICS

Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries

(2017) Valentina Boeva et al.   NATURE GENETICS

Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

(2017) Robin M Meyers et al.   NATURE GENETICS

Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla

(2017) Alessandro Furlan et al.   SCIENCE

The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers

(2017) Burak H. Alver et al.   Nature Communications

BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways

(2016) L Jubierre et al.   ONCOGENE

Small Molecules Modulate Chromatin Accessibility to Promote NEUROG2-Mediated Fibroblast-to-Neuron Reprogramming

(2016) Derek K. Smith et al.   Stem Cell Reports

Neuroblastoma

(2016) Katherine K. Matthay et al.   Nature Reviews Disease Primers

ViVar: A Comprehensive Platform for the Analysis and Visualization of Structural Genomic Variation

(2014) Tom Sante et al.   PLoS One

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

The midkine family of growth factors: diverse roles in nervous system formation and maintenance

(2013) C Winkler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

Focal DNA Copy Number Changes in Neuroblastoma Target MYCN Regulated Genes

(2013) Candy Kumps et al.   PLoS One

Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma

(2013) H Kocak et al.   Cell Death & Disease

Expanded clinical and experimental use of SOX11 - using a monoclonal antibody

(2012) Lena Nordström et al.   BMC CANCER

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

(2012) Jan J. Molenaar et al.   NATURE

LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression

(2012) Jan J Molenaar et al.   NATURE GENETICS

N-Cadherin in Neuroblastoma Disease: Expression and Clinical Significance

(2012) Tim Lammens et al.   PLoS One

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system

(2010) M. R. Potzner et al.   DEVELOPMENT

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

(2010) Pallavi Bhattaram et al.   Nature Communications

Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer

(2009) R. N. Jorissen et al.   CLINICAL CANCER RESEARCH

Genes that mediate breast cancer metastasis to the brain

(2009) Paula D. Bos et al.   NATURE

The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia

(2008) P. Van Vlierberghe et al.   BLOOD

Mutation of ERBB2 Provides a Novel Alternative Mechanism for the Ubiquitous Activation of RAS-MAPK in Ovarian Serous Low Malignant Potential Tumors

(2008) M. S. Anglesio et al.   MOLECULAR CANCER RESEARCH

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

(2008) Isabelle Janoueix-Lerosey et al.   NATURE

High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma

(2008) E. Fredlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA