All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals

In Vivo Whole-Cell Patch-Clamp Methods: Recent Technical Progress and Future Perspectives

(2021) Asako Noguchi et al.   SENSORS

BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons

(2021) Johannes Vierock et al.   Nature Communications

All-Optical Electrophysiology Reveals the Role of Lateral Inhibition in Sensory Processing in Cortical Layer 1

(2020) Linlin Z. Fan et al.   CELL

GABAergic motor neurons bias locomotor decision-making in C. elegans

(2020) Ping Liu et al.   Nature Communications

Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics

(2019) Yoav Adam et al.   NATURE

Rhodopsin-based voltage imaging tools for use in muscles and neurons of Caenorhabditis elegans

(2019) Negin Azimi Hashemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optical voltage imaging in neurons: moving from technology development to practical tool

(2019) Thomas Knöpfel et al.   NATURE REVIEWS NEUROSCIENCE

A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters

(2018) Kiryl D. Piatkevich et al.   Nature Chemical Biology

Rhodopsin optogenetic toolbox v2.0 for light-sensitive excitation and inhibition in Caenorhabditis elegans

(2018) Amelie Bergs et al.   PLoS One

Dynamic all-optical drug screening on cardiac voltage-gated ion channels

(2018) Jonas Streit et al.   Scientific Reports

Closing the Loop on Deep Brain Stimulation for Treatment-Resistant Depression

(2018) Alik S. Widge et al.   Frontiers in Neuroscience

C. elegans AWA Olfactory Neurons Fire Calcium-Mediated All-or-None Action Potentials

(2018) Qiang Liu et al.   CELL

Crystal structure of the red light-activated channelrhodopsin Chrimson

(2018) Kazumasa Oda et al.   Nature Communications

Light-Activated Dynamic Clamp Using iPSC-Derived Cardiomyocytes

(2018) Bonnie Quach et al.   BIOPHYSICAL JOURNAL

Fast, in vivo voltage imaging using a red fluorescent indicator

(2018) Madhuvanthi Kannan et al.   NATURE METHODS

High-efficiency optogenetic silencing with soma-targeted anion-conducting channelrhodopsins

(2018) Mathias Mahn et al.   Nature Communications

Targeting Neural Circuits

(2016) Priyamvada Rajasethupathy et al.   CELL

Genetically encoded indicators of neuronal activity

(2016) Michael Z Lin et al.   NATURE NEUROSCIENCE

Circuit modules linking internal states and social behaviour in flies and mice

(2016) David J. Anderson   NATURE REVIEWS NEUROSCIENCE

Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics

(2015) E. G. Govorunova et al.   SCIENCE

Optogenetic feedback control of neural activity

(2015) Jonathan P Newman et al.   eLife

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

(2014) Daniel R Hochbaum et al.   NATURE METHODS

Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons

(2014) Nicholas C. Flytzanis et al.   Nature Communications

Bright and fast multicoloured voltage reporters via electrochromic FRET

(2014) Peng Zou et al.   Nature Communications

Imaging neural spiking in brain tissue using FRET-opsin protein voltage sensors

(2014) Yiyang Gong et al.   Nature Communications

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

From the connectome to brain function

(2013) Cornelia I Bargmann et al.   NATURE METHODS

Enhanced Archaerhodopsin Fluorescent Protein Voltage Indicators

(2013) Yiyang Gong et al.   PLoS One

Mechanism of voltage-sensitive fluorescence in a microbial rhodopsin

(2013) D. Maclaurin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PKA Controls Calcium Influx into Motor Neurons during a Rhythmic Behavior

(2013) Han Wang et al.   PLoS Genetics

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

(2013) Jasper Akerboom et al.   Frontiers in Molecular Neuroscience

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury

(2012) Jeanne T Paz et al.   NATURE NEUROSCIENCE

Microbial Light-Activatable Proton Pumps as Neuronal Inhibitors to Functionally Dissect Neuronal Networks in C. elegans

(2012) Steven J. Husson et al.   PLoS One

Optical recording of action potentials in mammalian neurons using a microbial rhodopsin

(2011) Joel M Kralj et al.   NATURE METHODS

Action potentials drive body wall muscle contractions in Caenorhabditis elegans

(2011) S. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

(2010) Viviana Gradinaru et al.   CELL

Genetic dissection of ion currents underlying all-or-none action potentials in C. elegans body-wall muscle cells

(2010) P. Liu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Optogenetic analysis of synaptic function

(2008) Jana F Liewald et al.   NATURE METHODS