Buspirone Induces Weight Loss and Normalization of Blood Pressure via the Stimulation of PPARδ Dependent Energy Producing Pathway in Spontaneously Hypertensive Rats

Blocking VCAM-1 Prevents Angiotensin II-Induced Hypertension and Vascular Remodeling in Mice

(2022) Liangqingqing Yin et al.   Frontiers in Pharmacology

Targeting skeletal muscle mitochondrial health in obesity

(2022) Chantal A. Pileggi et al.   CLINICAL SCIENCE

Hypertension as a risk factor for atherosclerosis: Cardiovascular risk assessment

(2022) Anastasia V. Poznyak et al.   Frontiers in Cardiovascular Medicine

Contribution of PGC-1α to Obesity- and Caloric Restriction-Related Physiological Changes in White Adipose Tissue

(2021) Masaki Kobayashi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An anxiolytic drug buspirone ameliorates hyperglycemia and endothelial dysfunction in type 2 diabetic rat model

(2020) Tugba Gurpinar Çavuşoğlu et al.   Turkish Journal of Biochemistry-Turk Biyokimya Dergisi

Metformin prevents the development of monocrotaline‑induced pulmonary hypertension by decreasing serum levels of big endothelin‑1

(2020) Tomohiko Yoshida et al.   Experimental and Therapeutic Medicine

Brain Morphometry and Longitudinal Relaxation Time of Spontaneously Hypertensive Rats (SHRs) in Early and Intermediate Stages of Hypertension Investigated by 3D VFA-SPGR MRI

(2019) Sunil Koundal et al.   NEUROSCIENCE

Aster glehni Extract Containing Caffeoylquinic Compounds Protects Human Keratinocytes through the TRPV4-PPARδ-AMPK Pathway

(2018) Yong-Jik Lee et al.   Evidence-based Complementary and Alternative Medicine

6-Gingerol Normalizes the Expression of Biomarkers Related to Hypertension via PPARδ in HUVECs, HEK293, and Differentiated 3T3-L1 Cells

(2018) Yong-Jik Lee et al.   PPAR Research

Fimasartan Ameliorates Nonalcoholic Fatty Liver Disease through PPARδ Regulation in Hyperlipidemic and Hypertensive Conditions

(2017) Yong-Jik Lee et al.   PPAR Research

Serotonin Improves High Fat Diet Induced Obesity in Mice

(2016) Hitoshi Watanabe et al.   PLoS One

PGC-1α dictates endothelial function through regulation of eNOS expression

(2016) Siobhan M. Craige et al.   Scientific Reports

Obesity-related hypertension: possible pathophysiological mechanisms

(2014) Ivana Vaněčková et al.   JOURNAL OF ENDOCRINOLOGY

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

AMPK Activation through Mitochondrial Regulation Results in Increased Substrate Oxidation and Improved Metabolic Parameters in Models of Diabetes

(2013) Yonchu Jenkins et al.   PLoS One

PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion

(2012) E. Matthew Morris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Psychological and Psychiatric Aspects of Treatment of Obesity and Nonalcoholic Fatty Liver Disease

(2012) Karen E. Stewart et al.   Clinics in Liver Disease

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Changes in Body Weight and Psychotropic Drugs: A Systematic Synthesis of the Literature

(2012) Robert Dent et al.   PLoS One

Rosiglitazone Restores Endothelial Dysfunction in a Rat Model of Metabolic Syndrome through PPARγ- and PPARδ-Dependent Phosphorylation of Akt and eNOS

(2011) Zhigang Zhao et al.   PPAR Research

Telmisartan Prevents Weight Gain and Obesity Through Activation of Peroxisome Proliferator-Activated Receptor-δ–Dependent Pathways

(2010) Hongbo He et al.   HYPERTENSION

Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity

(2009) Woo Sik Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Expanded Biology of Serotonin

(2009) Miles Berger et al.   Annual Review of Medicine