Article
Food Science & Technology
F. Pinero-Garcia, R. Thomas, J. Mantero, E. Forssell-Aronsson, M. Isaksson
Summary: The study found that some brands of bottled water in the Swedish market exceeded the drinking water standard in terms of radioactive isotope content, primarily due to high activity concentrations of 238U, 234U, 210Po, and 210Pb.
Article
Instruments & Instrumentation
Jillian Elizabeth Moffatt, Thomas Bede Payten, Georgios Tsiminis, Thomas Jacob de Prinse, Lewis Da Silva Teixeira, Elizaveta Klantsataya, David John Ottaway, Barnaby Whitmore Smith, Nigel Antony Spooner
Summary: The study explores the potential application of upconversion fluorescence in real-time monitoring of fluorite, achieving a certain research progress by reducing false signals to improve detection thresholds. This technology can detect fluorite at rare earth concentrations as low as one part per million, making it a promising new method for real-time detection.
APPLIED SPECTROSCOPY
(2021)
Article
Plant Sciences
Aude Beauger, Carlos E. Wetzel, Elisabeth Allain, Clotilde Bertin, Olivier Voldoire, Vincent Breton, Lory-Anne Baker, Sofia Kolovi, David Biron, Luc Ector
Summary: A new species of Chamaepinnularia, named Chamaepinnularia salina, was discovered during a survey of mineral springs in the French Massif Central region. This species has distinct morphological characteristics and prefers mineral springs with a Na-K-HCO3 water type.
Article
Environmental Sciences
Javier Perez-Burillo, Greta Valoti, Andrzej Witkowski, Patricia Prado, David G. Mann, Rosa Trobajo
Summary: The study revealed the high-diversity diatom communities in the Ebro delta bays, with DNA metabarcoding effectively reflecting this diversity at the genus level. However, limitations were found at the species level due to the incompleteness of the DNA reference library. Combining LM and DNA approaches provides stronger support for ecological studies of benthic microalgal communities in shallow coastal environments.
MARINE POLLUTION BULLETIN
(2022)
Article
Multidisciplinary Sciences
Rachel S. Cueny, Sameer Varma, Kristina Schmidt, James Keck
Summary: Bloom syndrome helicase (BLM) is a RecQ-family helicase involved in various cellular processes. Mutations in human BLM cause Bloom syndrome (BS), leading to negative health impacts. Non-BS mutations of BLM, such as BLM P868L and BLM G1120R, increase sister chromatid exchanges. In vitro studies showed that these mutant proteins still retain helicase function. Another mutant protein, BLMcore K869A K870A, has diminished ATPase and helicase activity compared to wild-type BLMcore, suggesting the importance of a lysine-rich loop in BLM's functions.
Article
Ecology
Lester L. Yuan, Richard M. Mitchell, Amina Pollard, Christopher T. Nietch, Erik M. Pilgrim, Nathan J. Smucker
Summary: Changes in phosphorus concentrations have nuanced effects on periphytic diatom composition in streams, showing weak relationships with diatom richness. On the other hand, conductivity changes strongly influence both diatom composition and richness. By comparing the relationships between phosphorus and taxon occurrence with those between conductivity and taxon occurrence, as well as documenting the effects of niche breadths on richness patterns, a better understanding of the mechanisms controlling the phosphorus-richness relationship can be achieved. The findings contribute to improving the management of phosphorus pollution and describing the contributions of excess phosphorus and specific taxa with their niche breadths to diatom richness patterns.
FRESHWATER BIOLOGY
(2023)
Article
Chemistry, Physical
M. M. Mahfuz Siraz, Jubair Al Mahmud, M. S. Alam, Md. Bazlar Rashid, Zakir Hossain, Mayeen Uddin Khandaker, D. A. Bradley, M. M. H. Miah, B. Alshahrani, S. Yeasmin
Summary: In order to understand the potential health effects of radionuclides produced by coal-fired brick kilns, the first-ever measurements of terrestrial radionuclides were conducted in the topsoil surrounding a randomly chosen brick kiln in Dhaka, Bangladesh. The results showed that the activity concentrations of 226Ra, 232Th, and 40K were higher than the world average values, indicating health risks to brick kiln workers and consumers of crops grown in the studied agricultural soils. The findings emphasize the need for municipal authorities to manage and monitor fly ash discharge from brick kilns and take precautionary actions to reduce health hazards.
RADIATION PHYSICS AND CHEMISTRY
(2023)
Article
Pharmacology & Pharmacy
Conor J. Bloxham, Katina D. Hulme, Fabrizio Fierro, Christian Fercher, Cassandra L. Pegg, Shannon L. O'Brien, Simon R. Foster, Kirsty R. Short, Sebastian G. B. Furness, Melissa E. Reichelt, Masha Y. Niv, Walter G. Thomas
Summary: Bitter taste receptors (T2Rs) are a type of G protein-coupled receptors that allow humans to detect aversive and toxic substances. This study characterized the functional properties of previously identified T2Rs in human cardiac tissues and their naturally occurring polymorphisms. The results showed differences in signaling among different T2R variants, and revealed a potential association between the T2R50 Tyr203 variant and cardiovascular disease.
BIOCHEMICAL PHARMACOLOGY
(2024)
Article
Endocrinology & Metabolism
Gill Holdsworth, James R. Staley, Peter Hall, Ian van Koeverden, Ciara Vangjeli, Remi Okoye, Rogely W. Boyce, James R. Turk, Martin Armstrong, Alison Wolfreys, Gerard Pasterkamp
Summary: The study showed that most atherosclerotic plaques in patients at risk for cardiovascular disease lacked sclerostin, and its inhibition did not have a significant association with the risk of heart attacks in a population-based cohort study.
JOURNAL OF BONE AND MINERAL RESEARCH
(2021)
Article
Engineering, Marine
William G. Ambrose, Paul E. Renaud, David C. Adler, Robert L. Vadas
Summary: The study revealed that rock type significantly affects the attachment and persistence of brown algal zygotes, with differences in initial attachment and survival patterns among different rock types. Surface roughness was not found to be the predominant factor controlling successful attachment among rock types, suggesting that other properties of bedrock such as grain size, surface free energy, or chemical interaction with adhesives used by the zygotes play a direct role in attachment. These results indicate that benthic community structure patterns may be partly determined by the distribution of different bedrock types.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2021)
Review
Cell Biology
Chiaho Shih, Szu-Yao Wu, Shu-Fan Chou, Ta-Tung Thomas Yuan
Summary: Mutant 97L of HBc in chronic hepatitis B patients exhibits an immature secretion phenotype, contrary to the dogma of wild type HBV virion secretion predominantly containing mature double-stranded DNA genomes. Aberrant behaviors in virion secretion were observed in other naturally occurring HBc variants, possibly mediated by compensatory mutations. Virion secretion regulated by HBV genome maturity could be a potential target for antiviral drug development.
Article
Environmental Sciences
Frederic Rimet, Eveline Pinseel, Agnes Bouchez, Bella Japoshvili, Levan Mumladze
Summary: In this study, the population of diatoms in high-altitude lakes was investigated, and it was found that geographic barriers strongly limited dispersal at the sub-species level but not at the species level. These results have important implications for the development and selection of biomonitoring methods.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Javier Perez-Burillo, Rosa Trobajo, Manel Leira, Francois Keck, Frederic Rimet, Javier Sigro, David G. Mann
Summary: This study evaluates the genetic variants within several ecologically important diatom species and finds that different genetic variants within the same species show diverse distribution patterns and ecological preferences, with varying responses to environmental variables. The results demonstrate the importance of studying genetic variants within species complexes for understanding ecological tolerance and developing accurate biological indexes for biomonitoring programs.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biodiversity Conservation
Kalman Tapolczai, Geza B. Selmeczy, Beata Szabo, Viktoria B-Beres, Francois Keck, Agnes Bouchez, Frederic Rimet, Judit Padisak
Summary: This study assessed the impact of land-use on diatom assemblages using DNA metabarcoding and tested a taxonomy-free approach for a better interpretation of agricultural stress. Results showed that the taxonomy-free approach provided better insights into the effects of agricultural land use and could lead to the development of more efficient indices. Furthermore, it demonstrated the importance of retaining ecological information by using exact sequence variants without taxonomic assignment.
ECOLOGICAL INDICATORS
(2021)
Article
Cell Biology
Zsuzsa Bartos, Laszlo Homolya
Summary: Proper targeting of ABCG2 transporter to the plasma membrane is crucial for its function, with Q141K and M71V polymorphisms affecting cellular routing rather than transport function. A new experimental tool was used to study trafficking defects of these variants.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Sinziana F. Rivera, Frederic Rimet, Valentin Vasselon, Marine Vautier, Isabelle Domaizon, Agnes Bouchez
Summary: The study found that aquatic biofilms can effectively capture fish eDNA, providing a faster and more efficient way to monitor fish communities. Compared to traditional water filtration methods, biofilms showed similar richness and diversity, with differences mainly observed in rare taxa.
MOLECULAR ECOLOGY RESOURCES
(2022)
Review
Environmental Sciences
J. Pawlowski, K. Bruce, K. Panksep, F. Aguirre, S. Amalfitano, L. Apotheloz-Perret-Gentil, T. Baussant, A. Bouchez, L. Carugati, K. Cermakova, T. Cordier, C. Corinaldesi, F. O. Costa, R. Danovaro, A. Dell'Anno, S. Duarte, U. Eisendle, B. J. D. Ferrari, F. Frontalini, L. Fruehe, A. Haegerbaeumer, V Kisand, A. Krolicka, A. Lanzen, F. Leese, F. Lejzerowicz, E. Lyautey, I Macek, M. Sagova-Mareckova, J. K. Pearman, X. Pochon, T. Stoeck, R. Vivien, A. Weigand, S. Fazi
Summary: Environmental DNA (eDNA) metabarcoding is transforming aquatic biomonitoring by sequencing DNA/RNA to identify entire communities within a targeted group. Most studies have focused on water eDNA and macroinvertebrate samples, but eDNA metabarcoding has also been applied to soft sediment samples, especially for microbial or meiofaunal communities. Compared to traditional methods, eDNA metabarcoding offers advantages for assessing sediment environmental quality. However, there is a need for standardization to improve robustness and comparability. This review focuses on sampling, preservation, and DNA extraction protocols for sediment eDNA metabarcoding, aiming to identify best practices and promote harmonization for future benthic monitoring.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biochemistry & Molecular Biology
Heloise Verdier, Lara Konecny-Dupre, Christophe Marquette, Helen Reveron, Solene Tadier, Laurent Gremillard, Amelie Barthes, Thibault Datry, Agnes Bouchez, Tristan Lefebure
Summary: The study presents a concept validation of a passive, 3D-printed and easy-to-use eDNA sampler. The samplers, made from hydroxyapatite, efficiently collect genomic DNA and animal eDNA, but with variations in the amount of DNA collected. Further research on the DNA-hydroxyapatite interactions is needed to optimize eDNA adsorption and develop a reliable, easy-to-use, and reusable eDNA sampling tool.
MOLECULAR ECOLOGY RESOURCES
(2022)
Article
Plant Sciences
Aude Beauger, Carlos E. Wetzel, Elisabeth Allain, Clotilde Bertin, Olivier Voldoire, Vincent Breton, Lory-Anne Baker, Sofia Kolovi, David Biron, Luc Ector
Summary: A new species of Chamaepinnularia, named Chamaepinnularia salina, was discovered during a survey of mineral springs in the French Massif Central region. This species has distinct morphological characteristics and prefers mineral springs with a Na-K-HCO3 water type.
Article
Plant Sciences
Aude Beauger, Elisabeth Allain, Olivier Voldoire, Christelle Blavignac, Sofia Rossi, Carlos E. Wetzel, Luc Ector
Summary: A new species of Gomphosphenia was discovered in the diatom survey in the Vault de Chaudefour Nature Reserve in the Massif Central, France. This small-sized species has distinctive characteristics and seems to inhabit headwater streams.
Article
Plant Sciences
Bart Van de Vijver, Eduardo A. Morales, Tanja M. Schuster, Carlos E. Wetzel, Luc Ector
Summary: This study provides a detailed description of Staurosirella lapponica using microscopy and identifies a possible heterotypic synonym. Comparison with other elliptic Staurosirella species shows some similarities only with S. mutabilis.
Article
Plant Sciences
Eduardo A. Morales, Maria Helena Novais, Carlos E. Wetzel, Luc Ector, Maria Manuela Morais
Summary: A new species of Fragilaria, Fragilaria odeloucaensis sp. nov., is described from a temporary stream in southern Portugal. This species has unique features and its taxonomic position within Fragilaria is discussed through a detailed analysis of diagnostic features.
Article
Biochemistry & Molecular Biology
Frederic Rimet, Alexis Canino, Teofana Chonova, Julie Gueguen, Agnes Bouchez
Summary: This study found that diatom communities in Lake Geneva are primarily assembled through environmental filtering and immigration processes. Rivers bring communities that settle in the lake, especially in sites close to estuaries. Although other assembly rules may be at play, environmental filtering dominates in diatom communities.
Article
Environmental Sciences
Giuseppina G. Lai, Carlos E. Wetzel, Luc Ector, Antonella Luglie, Bachisio M. Padedda
Summary: This study analyzed diatom assemblages in thermal springs in Sardinia, Italy, and found that low discharge, ecotonal properties, and natural and human disturbances significantly affect the composition of the aquatic communities. Springs connected to rivers and with higher disturbance levels exhibited higher species richness and diversity, while isolated springs harbored smaller pools of taxa with specific habitat preferences or restricted distributions. Environmental variables such as water temperature, river influence, and nutrients also played a major role in shaping the diatom assemblages.
Article
Plant Sciences
Cheran Radhakrishnan, Sudipta Kumar Das, Carlos E. Wetzel, Balasubramanian Karthick
Summary: We describe a new species of Adlafia called Adlafia kociolekii from aerial habitats in Sikkim, India. The species was observed and described based on light and scanning electron microscopy observations. The main diagnostic features of this species include clear elliptical valves, a narrow axial area at the centre, radiate to convergent striation, and a distinctive Voigt discontinuity at both apices. The ultrastructure of this species, including the presence of a raphe on the elevated sternum, distal raphe ends deflected to opposite sides of proximal ends, and distal ends terminating in long and thickened helictoglossae, distinguishes it as a new species. The species was also found in wet walls and freshwater habitats in northeast India. Morphological features of this species were compared with closely similar taxa of Adlafia and other naviculoid genera.
Article
Plant Sciences
Bart Van De Vijver, Britt Gogne, Gabrielle Hoogsteyns, Levente Van De Velde, Luna Vlaminck, Sija A. Kabota, Lies Teunen, Carlos E. Wetzel
Article
Microbiology
Rayan Bouchali, Laurence Marjolet, Leslie Mondamert, Teofana Chonova, Sebastien Ribun, Elodie Laurent, Agnes Bouchez, Jerome Labanowski, Benoit Cournoyer
Summary: The study investigated the ability of bacteria in wastewater treatment plant (WWTP) outflows to colonize rock surfaces and contribute to the formation of river epilithic biofilms. The bacterial communities of biofilms developing on rocks exposed to treated wastewaters (TWW) from a hospital and a domestic clarifier, as well as surface waters of the stream at different distances from the WWTP outlet, were compared. The results revealed differences in bacterial contents and species composition among the biofilms depending on the source of treated wastewater. The analysis also highlighted the presence of multi-resistant bacteria and correlations between bacterial species and pharmaceutical concentrations in the biofilms.
Article
Biodiversity Conservation
Aude Beauger, Olivier Voldoire, Elisabeth Allain, Pierre Gosseaume, Christelle Blavignac, Lory-Anne Baker, Carlos E. E. Wetzel
Summary: This study evaluates the biodiversity of 79 mineral saline springs in the French Massif Central, focusing on species richness and diatom community composition. Physical and chemical factors were found to influence the richness and communities of diatoms, with hardness and certain ions being critical drivers of diatom community composition.
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
