Development of a selection assay for small guide RNAs that drive efficient site-directed RNA editing

Engineered circular ADAR-recruiting RNAs increase the efficiency and fidelity of RNA editing in vitro and in vivo

(2022) Zongyi Yi et al.   NATURE BIOTECHNOLOGY

Efficient in vitro and in vivo RNA editing via recruitment of endogenous ADARs using circular guide RNAs

(2022) Dhruva Katrekar et al.   NATURE BIOTECHNOLOGY

Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides

(2022) Prashant Monian et al.   NATURE BIOTECHNOLOGY

Landscape of adenosine-to-inosine RNA recoding across human tissues

(2022) Orshay Gabay et al.   Nature Communications

Evolutionary driving forces of A‐to‐I editing in metazoans

(2021) Yuange Duan et al.   Wiley Interdisciplinary Reviews-RNA

Site-directed RNA editing: recent advances and open challenges

(2021) Hamid Mansouri Khosravi et al.   RNA Biology

Challenges and Opportunities for Nucleic Acid Therapeutics

(2021) David R. Corey et al.   Nucleic Acid Therapeutics

Advances in oligonucleotide drug delivery

(2020) Thomas C. Roberts et al.   NATURE REVIEWS DRUG DISCOVERY

Asymmetric dimerization of adenosine deaminase acting on RNA facilitates substrate recognition

(2020) Alexander S Thuy-Boun et al.   NUCLEIC ACIDS RESEARCH

Precise RNA editing by recruiting endogenous ADARs with antisense oligonucleotides

(2019) Tobias Merkle et al.   NATURE BIOTECHNOLOGY

Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs

(2019) Liang Qu et al.   NATURE BIOTECHNOLOGY

Selective Recognition of RNA Substrates by ADAR Deaminase Domains

(2018) Yuru Wang et al.   BIOCHEMISTRY

RNA-Targeted Therapeutics

(2018) Stanley T. Crooke et al.   Cell Metabolism

Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery

(2018) Nicholas Thomford et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

mRNA-Based Protein Replacement Therapy for the Heart

(2018) Ajit Magadum et al.   MOLECULAR THERAPY

UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy

(2017) Tom Smith et al.   GENOME RESEARCH

Dynamic landscape and regulation of RNA editing in mammals

(2017) Meng How Tan et al.   NATURE

Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity

(2016) Melissa M Matthews et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Splice-switching antisense oligonucleotides as therapeutic drugs

(2016) Mallory A. Havens et al.   NUCLEIC ACIDS RESEARCH

The delivery of therapeutic oligonucleotides

(2016) Rudolph L. Juliano   NUCLEIC ACIDS RESEARCH

Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity

(2016) Melissa M Matthews et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2

(2015) Kelly J. Phelps et al.   NUCLEIC ACIDS RESEARCH

mRNA-based therapeutics — developing a new class of drugs

(2014) Ugur Sahin et al.   NATURE REVIEWS DRUG DISCOVERY

leeHom: adaptor trimming and merging for Illumina sequencing reads

(2014) Gabriel Renaud et al.   NUCLEIC ACIDS RESEARCH

RNA-Seq Analysis Identifies a Novel Set of Editing Substrates for Human ADAR2 Present in Saccharomyces cerevisiae

(2013) Tristan Eifler et al.   BIOCHEMISTRY

Tertiary structural elements determine the extent and specificity of messenger RNA editing

(2013) Leila E. Rieder et al.   Nature Communications

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

The intricate relationship between RNA structure, editing, and splicing

(2011) Leila E. Rieder et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS