RHOJ controls EMT-associated resistance to chemotherapy

Monoclonal antibodies to activated CDK4: use to investigate normal and cancerous cell cycle regulation and involvement of phosphorylations of p21 and p27

(2021) Katia Coulonval et al.   CELL CYCLE

NCCN Guidelines® Insights: Squamous Cell Skin Cancer, Version 1.2022

(2021) Chrysalyne D. Schmults et al.   Journal of the National Comprehensive Cancer Network

A fork in the road: Where homologous recombination and stalled replication fork protection part ways

(2020) Stephanie Tye et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Rhoj Is a Novel Target for Progression and Invasion of Glioblastoma by Impairing Cytoskeleton Dynamics

(2020) Mei Wang et al.   Neurotherapeutics

RHOAming Through the Nucleotide Excision Repair Pathway as a Mechanism of Cellular Response Against the Effects of UV Radiation

(2020) Yuli T. Magalhaes et al.   Frontiers in Cell and Developmental Biology

MKL1 Mediates TGF-β Induced RhoJ Transcription to Promote Breast Cancer Cell Migration and Invasion

(2020) Baoyu Chen et al.   Frontiers in Cell and Developmental Biology

Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress

(2020) Noa Lamm et al.   NATURE CELL BIOLOGY

RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance

(2019) Daniël A. Lionarons et al.   CANCER CELL

Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

(2019) Halil Bagci et al.   NATURE CELL BIOLOGY

Uncoupling fork speed and origin activity to identify the primary cause of replicative stress phenotypes

(2018) Sara Rodriguez-Acebes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SLFN11 Blocks Stressed Replication Forks Independently of ATR

(2018) Junko Murai et al.   MOLECULAR CELL

Proteome-wide identification of ubiquitin interactions using UbIA-MS

(2018) Xiaofei Zhang et al.   Nature Protocols

QCloud: A cloud-based quality control system for mass spectrometry-based proteomics laboratories

(2018) Cristina Chiva et al.   PLoS One

Nuclear F-actin and myosins drive relocalization of heterochromatic breaks

(2018) Christopher P. Caridi et al.   NATURE

Nuclear ARP2/3 drives DNA break clustering for homology-directed repair

(2018) Benjamin R. Schrank et al.   NATURE

Identification of the tumour transition states occurring during EMT

(2018) Ievgenia Pastushenko et al.   NATURE

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response

(2017) Andrew N. Blackford et al.   MOLECULAR CELL

EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

(2017) Tsukasa Shibue et al.   Nature Reviews Clinical Oncology

Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes

(2017) François Aymard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes

(2017) François Aymard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The RhoJ-BAD signaling network: An Achilles’ heel for BRAF mutant melanomas

(2017) Rolando Ruiz et al.   PLoS Genetics

Causes of death among cancer patients

(2016) NG Zaorsky et al.   ANNALS OF ONCOLOGY

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks

(2015) Martin R. Higgs et al.   MOLECULAR CELL

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-1/2 that promotes efficient DNA repair

(2015) Brittany J Belin et al.   eLife

Vascular RhoJ Is an Effective and Selective Target for Tumor Angiogenesis and Vascular Disruption

(2014) Chan Kim et al.   CANCER CELL

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1

(2014) Peijing Zhang et al.   NATURE CELL BIOLOGY

Oncogenic roles of EMT-inducing transcription factors

(2014) Alain Puisieux et al.   NATURE CELL BIOLOGY

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Replication Dynamics: Biases and Robustness of DNA Fiber Analysis

(2013) Hervé Técher et al.   JOURNAL OF MOLECULAR BIOLOGY

RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection

(2013) J. Ross Chapman et al.   MOLECULAR CELL

Repriming of DNA synthesis at stalled replication forks by human PrimPol

(2013) Silvana Mourón et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RhoJ Regulates Melanoma Chemoresistance by Suppressing Pathways That Sense DNA Damage

(2012) H. Ho et al.   CANCER RESEARCH

Skin squamous cell carcinoma propagating cells increase with tumour progression and invasiveness

(2012) Gaëlle Lapouge et al.   EMBO JOURNAL

RhoJ modulates melanoma invasion by altering actin cytoskeletal dynamics

(2012) Hsiang Ho et al.   Pigment Cell & Melanoma Research

Active maintenance of nuclear actin by importin 9 supports transcription

(2012) J. Dopie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A requirement for polymerized actin in DNA double-strand break repair

(2012) Christi Andrin et al.   Nucleus

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

Identifying the cellular origin of squamous skin tumors

(2011) G. Lapouge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RhoJ/TCL Regulates Endothelial Motility and Tube Formation and Modulates Actomyosin Contractility and Focal Adhesion Numbers

(2010) Sukhbir Kaur et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

Chk1 promotes replication fork progression by controlling replication initiation

(2010) E. Petermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Twist1-Mediated Adriamycin-Induced Epithelial-Mesenchymal Transition Relates to Multidrug Resistance and Invasive Potential in Breast Cancer Cells

(2009) Q.-Q. Li et al.   CLINICAL CANCER RESEARCH

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication

(2008) Arkaitz Ibarra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA